GPM77700007010: KEGG pathway display model | context | group | gel | chip | peptide | table | details | GO | path | snaps | mh | XML | wiki | assigned accession: GPM77700007010

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KEGG ID	Pathway	log(I)	log(p)	Protein Description
rno:00010	Glycolysis / Gluconeogenesis	5.4	-11.4	14/1 proteins of 87 RGD1564781 (-220.7): gpmDB | homo | protein Alpha-enolase (EC 4.2.1.11)(2-phospho-D-glycerate hydro-lyase)(Non-neural enolase)(NNE)(Enolase 1) Source: UniProtKB/Swiss-Prot P04764 IPR000941 Enolase IPR020810 Enolase C IPR020809 Enolase CS IPR020811 Enolase N ENSRNOP00000049742 (-150.3): gpmDB | homo | protein KPYM_RAT Isoform M2 of P11980 - Rattus norvegicus (Rat) [Source:UniProtKB/SpliceVariant;Acc:P11980-2] IPR001697 Pyr Knase IPR015795 Pyrv Knase C-like IPR015794 Pyrv Knase a/b IPR015793 Pyrv Knase brl Ldhb (-94.5): gpmDB | homo | protein L-lactate dehydrogenase B chain (LDH-B)(EC 1.1.1.27)(LDH heart subunit)(LDH-H) Source: UniProtKB/Swiss-Prot P42123 IPR001557 L-lactate/malate DH IPR011304 L-lactate DH IPR018177 L-lactate DH AS IPR001236 Lactate/malate DH IPR015955 Lactate DH/Glyco Ohase 4 C IPR016040 NAD(P)-bd dom IPR001806 Ras GTPase RGD1562815 (-79.8): gpmDB | homo | protein no description available IPR020830 GlycerAld 3-P DH AS IPR020828 GlycerAld 3-P DH NAD(P) bd IPR020829 GlycerAld 3-P DH cat IPR020832 GlycerAld 3-P DH cat sub IPR020831 GlycerAld 3-P DH family IPR006424 Glyceraldehyde-3-P DH 1 IPR016040 NAD(P)-bd dom RGD1564433 (-56.1): gpmDB | homo | protein Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)(EC 1.2.1.12)(38 kDa BFA-dependent ADP-ribosylation substrate)(BARS-38) Source: UniProtKB/Swiss-Prot P04797 IPR020830 GlycerAld 3-P DH AS IPR020828 GlycerAld 3-P DH NAD(P) bd IPR020829 GlycerAld 3-P DH cat IPR020832 GlycerAld 3-P DH cat sub Eno2 (-47.1): gpmDB | homo | protein Gamma-enolase (EC 4.2.1.11)(2-phospho-D-glycerate hydro-lyase)(Neural enolase)(Neuron-specific enolase)(NSE)(Enolase 2) Source: UniProtKB/Swiss-Prot P07323 IPR000941 Enolase IPR020810 Enolase C IPR020809 Enolase CS IPR020811 Enolase N LOC365784 (-42.7): gpmDB | homo | protein Fructose-bisphosphate aldolase A (EC 4.1.2.13)(Muscle-type aldolase) Source: UniProtKB/Swiss-Prot P05065 IPR000741 Aldolase I ENSRNOP00000012585 (-41.6): gpmDB | homo | protein no description available IPR001557 L LDH MDH IPR011304 L LDH NAD IPR001236 Lactate/malate DH IPR015955 Lactate DH/Glyco hydro 4 C IPR001806 Ras trnsfrmng Pgk1 (-35.4): gpmDB | homo | protein Phosphoglycerate kinase 1 (EC 2.7.2.3) Source: UniProtKB/Swiss-Prot P16617 IPR001576 Phosphoglycerate kinase IPR015911 Phosphoglycerate kinase CS Gpi (-32.3): gpmDB | homo | protein Glucose-6-phosphate isomerase (GPI)(EC 5.3.1.9)(Phosphoglucose isomerase)(PGI)(Phosphohexose isomerase)(PHI)(Autocrine motility factor)(AMF)(Neuroleukin)(NLK) Source: UniProtKB/Swiss-Prot Q6P6V0 IPR001672 G6P Isomerase IPR018189 Phosphoglucose isomerase CS Aldh9a1 (-28.6): gpmDB | homo | protein 4-trimethylaminobutyraldehyde dehydrogenase (TMABADH)(EC 1.2.1.47)(Aldehyde dehydrogenase family 9 member A1)(EC 1.2.1.3) Source: UniProtKB/Swiss-Prot Q9JLJ3 ENSRNOP00000046460 (-25.8): gpmDB | homo | protein no description available IPR002347 ADH short C2 IPR000173 GAP DH ENSRNOP00000039702 (-25.2): gpmDB | homo | protein triosephosphate isomerase Source: RefSeq_peptide NP_001028244 IPR000652 Triophos ismrse Pgm1 (-18.0): gpmDB | homo | protein Phosphoglucomutase-1 (PGM 1)(EC 5.4.2.2)(Glucose phosphomutase 1) Source: UniProtKB/Swiss-Prot P38652 IPR005843 A-D-PHexomutase C IPR016066 A-D-PHexomutase CS IPR005841 A-D-PHexomutase N IPR005844 A-D-PHexomutase a/b/a-I IPR016055 A-D-PHexomutase a/b/a-I/II/III IPR005845 A-D-PHexomutase a/b/a-II IPR005846 A-D-PHexomutase a/b/a-III
rno:04612	Antigen processing and presentation	5.5	-6.0	9/1 proteins of 93 LOC682160 (-293.0): gpmDB | homo | protein Heat shock protein HSP 90-alpha (Heat shock 86 kDa)(HSP 86)(HSP86) Source: UniProtKB/Swiss-Prot P82995 IPR003594 ATP bd ATPase IPR001404 Chaperone htpG IPR019805 Heat shock protein 90 CS IPR020576 Hsp90 C IPR020575 Hsp90 N IPR020568 Ribosomal S5 D2-typ fold LOC679973 (-289.2): gpmDB | homo | protein Heat shock protein HSP 90-beta (Heat shock 84 kDa)(HSP 84)(HSP84) Source: UniProtKB/Swiss-Prot P34058 IPR003594 ATP bd ATPase IPR001404 Chaperone htpG IPR019805 Heat shock protein 90 CS IPR020576 Hsp90 C IPR020575 Hsp90 N IPR020568 Ribosomal S5 D2-typ fold Pdia3 (-287.0): gpmDB | homo | protein Protein disulfide-isomerase A3 Precursor (EC 5.3.4.1)(Disulfide isomerase ER-60)(Endoplasmic reticulum resident protein 60)(ER protein 60)(ERp60)(Endoplasmic reticulum resident protein 57)(ER protein 57)(ERp57)(58 kDa microsomal protein)(p58)(HIP-70 /.../(58 kDa glucose-regulated protein) Source: UniProtKB/Swiss-Prot P11598 IPR005788 Disulphide isomerase IPR005792 Prot disulphide isomerase IPR012336 Thioredoxin-like fold IPR006662 Thioredoxin-like subdom IPR017937 Thioredoxin CS IPR013766 Thioredoxin domain Hspa5 (-275.2): gpmDB | homo | protein 78 kDa glucose-regulated protein Precursor (GRP-78)(Heat shock 70 kDa protein 5)(Immunoglobulin heavy chain-binding protein)(BiP)(Steroidogenesis-activator polypeptide) Source: UniProtKB/Swiss-Prot P06761 IPR018181 Heat shock 70 CS IPR001023 Hsp70 IPR013126 Hsp 70 RGD1559849 (-259.7): gpmDB | homo | protein no description available IPR018181 Heat shock 70 CS IPR001023 Hsp70 IPR013126 Hsp 70 Calr (-196.0): gpmDB | homo | protein Calreticulin Precursor (CRP55)(Calregulin)(HACBP)(Endoplasmic reticulum resident protein 60)(ERp60)(CALBP)(Calcium-binding protein 3)(CABP3) Source: UniProtKB/Swiss-Prot P18418 IPR001580 Calret/calnex IPR018124 Calret/calnex CS IPR009169 Calreticulin IPR008985 ConA-like lec gl Hspa2 (-86.0): gpmDB | homo | protein Heat shock-related 70 kDa protein 2 (Heat shock protein 70.2)(Testis-specific heat shock protein-related)(HST) Source: UniProtKB/Swiss-Prot P14659 IPR018181 Heat shock 70 CS IPR001023 Hsp70 IPR013126 Hsp 70 Hspa4 (-72.8): gpmDB | homo | protein Heat shock 70 kDa protein 4 (Ischemia responsive 94 kDa protein) Source: UniProtKB/Swiss-Prot O88600 IPR018181 Heat shock 70 CS IPR001023 Hsp70 IPR013126 Hsp 70 ENSRNOP00000040859 (-49.3): gpmDB | homo | protein Calnexin Precursor Source: UniProtKB/Swiss-Prot P35565 IPR001580 Calret/calnex IPR018124 Calret/calnex CS IPR008985 ConA-like lec gl
rno:00620	Pyruvate metabolism	4.7	-5.0	8/0 proteins of 38 ENSRNOP00000049742 (-150.3): gpmDB | homo | protein KPYM_RAT Isoform M2 of P11980 - Rattus norvegicus (Rat) [Source:UniProtKB/SpliceVariant;Acc:P11980-2] IPR001697 Pyr Knase IPR015795 Pyrv Knase C-like IPR015794 Pyrv Knase a/b IPR015793 Pyrv Knase brl Mdh2 (-96.3): gpmDB | homo | protein Malate dehydrogenase, mitochondrial Precursor (EC 1.1.1.37) Source: UniProtKB/Swiss-Prot P04636 IPR001557 L-lactate/malate DH IPR001236 Lactate/malate DH IPR015955 Lactate DH/Glyco Ohase 4 C IPR001252 Malate DH AS IPR010097 Malate DH NAD-dep euk/g-bac IPR016040 NAD(P)-bd dom Ldhb (-94.5): gpmDB | homo | protein L-lactate dehydrogenase B chain (LDH-B)(EC 1.1.1.27)(LDH heart subunit)(LDH-H) Source: UniProtKB/Swiss-Prot P42123 IPR001557 L-lactate/malate DH IPR011304 L-lactate DH IPR018177 L-lactate DH AS IPR001236 Lactate/malate DH IPR015955 Lactate DH/Glyco Ohase 4 C IPR016040 NAD(P)-bd dom IPR001806 Ras GTPase Mdh1 (-65.8): gpmDB | homo | protein Malate dehydrogenase, cytoplasmic (EC 1.1.1.37)(Cytosolic malate dehydrogenase) Source: UniProtKB/Swiss-Prot O88989 IPR001557 L-lactate/malate DH IPR001236 Lactate/malate DH IPR015955 Lactate DH/Glyco Ohase 4 C IPR001252 Malate DH AS IPR011274 Malate DH NAD-dep euk IPR010945 Malate DH SF1 IPR016040 NAD(P)-bd dom ENSRNOP00000012585 (-41.6): gpmDB | homo | protein no description available IPR001557 L LDH MDH IPR011304 L LDH NAD IPR001236 Lactate/malate DH IPR015955 Lactate DH/Glyco hydro 4 C IPR001806 Ras trnsfrmng Aldh9a1 (-28.6): gpmDB | homo | protein 4-trimethylaminobutyraldehyde dehydrogenase (TMABADH)(EC 1.2.1.47)(Aldehyde dehydrogenase family 9 member A1)(EC 1.2.1.3) Source: UniProtKB/Swiss-Prot Q9JLJ3 Acat1 (-12.6): gpmDB | homo | protein Acetyl-CoA acetyltransferase, mitochondrial Precursor (EC 2.3.1.9)(Acetoacetyl-CoA thiolase) Source: UniProtKB/Swiss-Prot P17764 IPR002155 Thiolase IPR016039 Thiolase-like IPR020610 Thiolase AS IPR020617 Thiolase C IPR020613 Thiolase CS IPR020616 Thiolase N IPR020615 Thiolase acyl enz int AS Akr1b1-ps2 (-6.2): gpmDB | homo | protein Aldose reductase (AR)(EC 1.1.1.21)(Aldehyde reductase) Source: UniProtKB/Swiss-Prot P07943 IPR001395 Aldo/ket red IPR018170 Aldo/ket reductase CS IPR020471 Aldo/keto reductase sg
rno:04540	Gap junction	5.5	-5.0	8/1 proteins of 82 Tubb2c (-298.5): gpmDB | homo | protein Tubulin beta-2C chain Source: UniProtKB/Swiss-Prot Q6P9T8 IPR002452 Alpha tubulin IPR013838 Beta-tubulin BS IPR002453 Beta tubulin IPR000158 Cell division FtsZ N IPR002967 Delta tubulin IPR004057 Epsilon tubulin IPR002454 Gamma tubulin IPR008280 Tub FtsZ C IPR000217 Tubulin IPR018316 Tubulin/FtsZ 2-layer-sand-dom IPR017975 Tubulin CS IPR003008 Tubulin FtsZ GTPase IPR019746 Tubulin FtsZ N Tubb5 (-252.5): gpmDB | homo | protein Tubulin beta-5 chain Source: UniProtKB/Swiss-Prot P69897 IPR002452 Alpha tubulin IPR013838 Beta-tubulin BS IPR002453 Beta tubulin IPR000158 Cell division FtsZ N IPR002967 Delta tubulin IPR004057 Epsilon tubulin IPR002454 Gamma tubulin IPR008280 Tub FtsZ C IPR000217 Tubulin IPR018316 Tubulin/FtsZ 2-layer-sand-dom IPR017975 Tubulin CS IPR003008 Tubulin FtsZ GTPase IPR019746 Tubulin FtsZ N Tuba1a (-230.7): gpmDB | homo | protein Tubulin alpha-1A chain (Tubulin alpha-1 chain)(Alpha-tubulin 1) Source: UniProtKB/Swiss-Prot P68370 IPR002452 Alpha tubulin IPR002453 Beta tubulin IPR000158 Cell division FtsZ N IPR002967 Delta tubulin IPR004057 Epsilon tubulin IPR002454 Gamma tubulin IPR008280 Tub FtsZ C IPR000217 Tubulin IPR018316 Tubulin/FtsZ 2-layer-sand-dom IPR017975 Tubulin CS IPR003008 Tubulin FtsZ GTPase IPR019746 Tubulin FtsZ N Tubb2b (-228.8): gpmDB | homo | protein Tubulin beta-2B chain (T beta-15) [Source: UniProt Q3KRE8] IPR013838 Beta-tubulin BS IPR008280 Tub FtsZ C IPR018316 Tubulin/FtsZ 2-layer-sand-dom IPR017975 Tubulin CS IPR003008 Tubulin FtsZ GTPase IPR019746 Tubulin FtsZ N Tuba4a (-163.8): gpmDB | homo | protein Tubulin alpha-4A chain (Tubulin alpha-4 chain)(Alpha-tubulin 4) Source: UniProtKB/Swiss-Prot Q5XIF6 IPR002452 Alpha tubulin IPR002453 Beta tubulin IPR000158 Cell division FtsZ N IPR002967 Delta tubulin IPR004057 Epsilon tubulin IPR002454 Gamma tubulin IPR008280 Tub FtsZ C IPR000217 Tubulin IPR018316 Tubulin/FtsZ 2-layer-sand-dom IPR017975 Tubulin CS IPR003008 Tubulin FtsZ GTPase IPR019746 Tubulin FtsZ N Tubb3 (-161.1): gpmDB | homo | protein Tubulin beta-3 chain (Neuron-specific class III beta-tubulin) Source: UniProtKB/Swiss-Prot Q4QRB4 IPR002452 Alpha tubulin IPR013838 Beta-tubulin BS IPR002453 Beta tubulin IPR000158 Cell division FtsZ N IPR002967 Delta tubulin IPR004057 Epsilon tubulin IPR002454 Gamma tubulin IPR008280 Tub FtsZ C IPR000217 Tubulin IPR018316 Tubulin/FtsZ 2-layer-sand-dom IPR017975 Tubulin CS IPR003008 Tubulin FtsZ GTPase IPR019746 Tubulin FtsZ N Tubb6 (-96.7): gpmDB | homo | protein tubulin, beta 6 [Source:RefSeq peptide;Acc:NP_001020846] IPR002452 Alpha tubulin IPR013838 Beta-tubulin BS IPR002453 Beta tubulin IPR000158 Cell division FtsZ N IPR002967 Delta tubulin IPR004057 Epsilon tubulin IPR002454 Gamma tubulin IPR008280 Tub FtsZ C IPR000217 Tubulin IPR018316 Tubulin/FtsZ 2-layer-sand-dom IPR017975 Tubulin CS IPR003008 Tubulin FtsZ GTPase IPR019746 Tubulin FtsZ N Gnai2 (-15.3): gpmDB | homo | protein Guanine nucleotide-binding protein G(i) subunit alpha-2 (Adenylate cyclase-inhibiting G alpha protein) Source: UniProtKB/Swiss-Prot P04897 IPR006688 ARF IPR002975 Fungi GproteinA IPR001019 Gprotein alph bd IPR000469 Gprotein alpha12 IPR001408 Gprotein alpha I IPR000367 Gprotein alpha S IPR001806 Ras GTPase
rno:01100	Metabolic pathways	5.6	-4.6	40/20 proteins of 1061 RGD1564781 (-220.7): gpmDB | homo | protein Alpha-enolase (EC 4.2.1.11)(2-phospho-D-glycerate hydro-lyase)(Non-neural enolase)(NNE)(Enolase 1) Source: UniProtKB/Swiss-Prot P04764 IPR000941 Enolase IPR020810 Enolase C IPR020809 Enolase CS IPR020811 Enolase N Aco2 (-218.4): gpmDB | homo | protein Aconitate hydratase, mitochondrial Precursor (Aconitase)(EC 4.2.1.3)(Citrate hydro-lyase) Source: UniProtKB/Swiss-Prot Q9ER34 IPR001030 Acoase/IPM deHydtase lsu aba IPR015928 Aconitase/3IPM dehydase swvl IPR000573 AconitaseA/IPMdHydase ssu swvl IPR018136 Aconitase 4Fe-4S BS IPR006248 Aconitase mito-like IPR020610 Thiolase AS Atp5a1 (-179.1): gpmDB | homo | protein ATP synthase subunit alpha, mitochondrial Precursor Source: UniProtKB/Swiss-Prot P15999 IPR005294 ATPase F1-cplx asu IPR018118 ATPase F1/A1-cplx a/bsu N IPR000793 ATPase F1/V1/A1-cplx a/bsu C IPR004100 ATPase F1/V1/A1-cplx a/bsu N IPR020003 ATPase F1/V1/A1 a/bsu AS IPR000194 ATPase F1/V1/A1 a/bsu nucl-bd LOC365654 (-163.3): gpmDB | homo | protein ATP synthase subunit beta, mitochondrial Precursor (EC 3.6.3.14) Source: UniProtKB/Swiss-Prot P10719 IPR003593 ATPase AAA+ core IPR005722 ATPase F1-cplx bsu IPR018118 ATPase F1/A1-cplx a/bsu N IPR000793 ATPase F1/V1/A1-cplx a/bsu C IPR004100 ATPase F1/V1/A1-cplx a/bsu N IPR020003 ATPase F1/V1/A1 a/bsu AS IPR000194 ATPase F1/V1/A1 a/bsu nucl-bd ENSRNOP00000049742 (-150.3): gpmDB | homo | protein KPYM_RAT Isoform M2 of P11980 - Rattus norvegicus (Rat) [Source:UniProtKB/SpliceVariant;Acc:P11980-2] IPR001697 Pyr Knase IPR015795 Pyrv Knase C-like IPR015794 Pyrv Knase a/b IPR015793 Pyrv Knase brl LOC314123 (-110.0): gpmDB | homo | protein Aspartate aminotransferase, mitochondrial Precursor (mAspAT)(EC 2.6.1.1)(Transaminase A)(Glutamate oxaloacetate transaminase 2)(Fatty acid-binding protein)(FABP-1)(Plasma membrane-associated fatty acid-binding protein)(FABPpm) Source: UniProtKB/Swiss-Prot P00507 IPR004839 Aminotrans I/II IPR000796 Asp trans IPR008120 Dense granule Gra7 protein IPR004838 NHTrfase class1 PyrdxlP-BS IPR015424 PyrdxlP-dep Trfase major Ckb (-100.1): gpmDB | homo | protein Creatine kinase B-type (EC 2.7.3.2)(Creatine kinase B chain)(B-CK) Source: UniProtKB/Swiss-Prot P07335 IPR000749 ATP-guanido PTrfase Mdh2 (-96.3): gpmDB | homo | protein Malate dehydrogenase, mitochondrial Precursor (EC 1.1.1.37) Source: UniProtKB/Swiss-Prot P04636 IPR001557 L-lactate/malate DH IPR001236 Lactate/malate DH IPR015955 Lactate DH/Glyco Ohase 4 C IPR001252 Malate DH AS IPR010097 Malate DH NAD-dep euk/g-bac IPR016040 NAD(P)-bd dom Ldhb (-94.5): gpmDB | homo | protein L-lactate dehydrogenase B chain (LDH-B)(EC 1.1.1.27)(LDH heart subunit)(LDH-H) Source: UniProtKB/Swiss-Prot P42123 IPR001557 L-lactate/malate DH IPR011304 L-lactate DH IPR018177 L-lactate DH AS IPR001236 Lactate/malate DH IPR015955 Lactate DH/Glyco Ohase 4 C IPR016040 NAD(P)-bd dom IPR001806 Ras GTPase RGD1562815 (-79.8): gpmDB | homo | protein no description available IPR020830 GlycerAld 3-P DH AS IPR020828 GlycerAld 3-P DH NAD(P) bd IPR020829 GlycerAld 3-P DH cat IPR020832 GlycerAld 3-P DH cat sub IPR020831 GlycerAld 3-P DH family IPR006424 Glyceraldehyde-3-P DH 1 IPR016040 NAD(P)-bd dom ENSRNOP00000026794 (-71.7): gpmDB | homo | protein neutral alpha-glucosidase AB [Source:RefSeq peptide;Acc:NP_001099804] IPR000322 Glyco hydro 31 IPR017853 Glyco hydro catalytic core Mdh1 (-65.8): gpmDB | homo | protein Malate dehydrogenase, cytoplasmic (EC 1.1.1.37)(Cytosolic malate dehydrogenase) Source: UniProtKB/Swiss-Prot O88989 IPR001557 L-lactate/malate DH IPR001236 Lactate/malate DH IPR015955 Lactate DH/Glyco Ohase 4 C IPR001252 Malate DH AS IPR011274 Malate DH NAD-dep euk IPR010945 Malate DH SF1 IPR016040 NAD(P)-bd dom RGD1564433 (-56.1): gpmDB | homo | protein Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)(EC 1.2.1.12)(38 kDa BFA-dependent ADP-ribosylation substrate)(BARS-38) Source: UniProtKB/Swiss-Prot P04797 IPR020830 GlycerAld 3-P DH AS IPR020828 GlycerAld 3-P DH NAD(P) bd IPR020829 GlycerAld 3-P DH cat IPR020832 GlycerAld 3-P DH cat sub Tkt (-52.6): gpmDB | homo | protein Transketolase (TK)(EC 2.2.1.1) Source: UniProtKB/Swiss-Prot P50137 IPR005476 Transketo C IPR009014 Transketo C/Pyr-ferredox oxred IPR005474 Transketo N IPR005475 Transketolase-like Pyr-bd IPR020826 Transketolase BS Eno2 (-47.1): gpmDB | homo | protein Gamma-enolase (EC 4.2.1.11)(2-phospho-D-glycerate hydro-lyase)(Neural enolase)(Neuron-specific enolase)(NSE)(Enolase 2) Source: UniProtKB/Swiss-Prot P07323 IPR000941 Enolase IPR020810 Enolase C IPR020809 Enolase CS IPR020811 Enolase N Psat1 (-46.3): gpmDB | homo | protein phosphoserine aminotransferase 1 [Source:RefSeq peptide;Acc:NP_942033] IPR000192 Aminotrans V/Cys dSase IPR020578 Aminotrans V PyrdxlP BS IPR003248 Pser amintransf IPR015424 PyrdxlP-dep Trfase major LOC365784 (-42.7): gpmDB | homo | protein Fructose-bisphosphate aldolase A (EC 4.1.2.13)(Muscle-type aldolase) Source: UniProtKB/Swiss-Prot P05065 IPR000741 Aldolase I ENSRNOP00000012585 (-41.6): gpmDB | homo | protein no description available IPR001557 L LDH MDH IPR011304 L LDH NAD IPR001236 Lactate/malate DH IPR015955 Lactate DH/Glyco hydro 4 C IPR001806 Ras trnsfrmng Cat (-35.7): gpmDB | homo | protein Catalase (EC 1.11.1.6) Source: UniProtKB/Swiss-Prot P04762 IPR002226 Catalase IPR020835 Catalase-like haem-dep IPR018028 Catalase rel subgroup Pgk1 (-35.4): gpmDB | homo | protein Phosphoglycerate kinase 1 (EC 2.7.2.3) Source: UniProtKB/Swiss-Prot P16617 IPR001576 Phosphoglycerate kinase IPR015911 Phosphoglycerate kinase CS Gpi (-32.3): gpmDB | homo | protein Glucose-6-phosphate isomerase (GPI)(EC 5.3.1.9)(Phosphoglucose isomerase)(PGI)(Phosphohexose isomerase)(PHI)(Autocrine motility factor)(AMF)(Neuroleukin)(NLK) Source: UniProtKB/Swiss-Prot Q6P6V0 IPR001672 G6P Isomerase IPR018189 Phosphoglucose isomerase CS RGD1559750 (-29.4): gpmDB | homo | protein Bifunctional purine biosynthesis protein PURH [Includes Phosphoribosylaminoimidazolecarboxamide formyltransferase(EC 2.1.2.3)(5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase)(AICAR transformylase);IMP cyclohydrolase(EC 3.5.4.10)(Inos /.../e)(IMP synthetase)(ATIC)] Source: UniProtKB/Swiss-Prot O35567 IPR002695 AICARFT IMPCHas IPR013982 AICARFT IMPCHas formly IPR011607 MGS Aldh9a1 (-28.6): gpmDB | homo | protein 4-trimethylaminobutyraldehyde dehydrogenase (TMABADH)(EC 1.2.1.47)(Aldehyde dehydrogenase family 9 member A1)(EC 1.2.1.3) Source: UniProtKB/Swiss-Prot Q9JLJ3 ENSRNOP00000046460 (-25.8): gpmDB | homo | protein no description available IPR002347 ADH short C2 IPR000173 GAP DH ENSRNOP00000039702 (-25.2): gpmDB | homo | protein triosephosphate isomerase Source: RefSeq_peptide NP_001028244 IPR000652 Triophos ismrse Ndufs1 (-24.5): gpmDB | homo | protein NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial Precursor (EC 1.6.5.3)(EC 1.6.99.3) [Source: UniProt Q66HF1] Source: 1.6.5.3 IPR001041 Ferredoxin IPR006656 Mopterin OxRdtase IPR000283 NADH UbQ OxRdtase 75KDa su CS IPR010228 NADH UbQ OxRdtase Gsu IPR015405 NuoG C ENSRNOP00000010209 (-24.2): gpmDB | homo | protein Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 Precursor (EC 2.4.1.119)(Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit)(Ribophorin-2)(Ribophorin II)(RPN-II) Source: UniProtKB/Swiss-Prot P25235 Atp6v1b2 (-20.5): gpmDB | homo | protein V-type proton ATPase subunit B, brain isoform (V-ATPase subunit B 2)(Vacuolar proton pump subunit B 2)(Endomembrane proton pump 58 kDa subunit) Source: UniProtKB/Swiss-Prot P62815 IPR000793 ATPase F1/V1/A1-cplx a/bsu C IPR004100 ATPase F1/V1/A1-cplx a/bsu N IPR020003 ATPase F1/V1/A1 a/bsu AS IPR000194 ATPase F1/V1/A1 a/bsu nucl-bd IPR005723 ATPase V1-cplx bsu Glud1 (-20.4): gpmDB | homo | protein Glutamate dehydrogenase 1, mitochondrial Precursor (GDH 1)(EC 1.4.1.3)(Memory-related gene 2 protein)(MRG-2) Source: UniProtKB/Swiss-Prot P10860 IPR006095 Glu/Leu/Phe/Val DH IPR006096 Glu/Leu/Phe/Val DH C IPR006097 Glu/Leu/Phe/Val DH dimer IPR016040 NAD(P)-bd dom LOC500370 (-18.5): gpmDB | homo | protein Adenosylhomocysteinase (AdoHcyase)(EC 3.3.1.1)(S-adenosyl-L-homocysteine hydrolase) Source: UniProtKB/Swiss-Prot P10760 IPR015878 Ado hCys hydrolase NAD-bd IPR000043 S-Ado-L-homoCys hydrolase IPR020082 S-Ado-L-homoCys hydrolase CS Cs (-18.1): gpmDB | homo | protein Citrate synthase, mitochondrial Precursor (EC 2.3.3.1) Source: UniProtKB/Swiss-Prot Q8VHF5 IPR002020 Citrate synthase-like IPR016141 Citrate synthase-like core IPR019810 Citrate synthase AS IPR010109 Citrate synthase euk Oat (-18.0): gpmDB | homo | protein Ornithine aminotransferase, mitochondrial Precursor (EC 2.6.1.13)(Ornithine--oxo-acid aminotransferase) [Source: UniProt P04182] Source: 2.6.1.13 IPR005814 Aminotrans 3 IPR013048 Meiotic Spo11 IPR010164 Orn aminotrans IPR015424 PyrdxlP-dep Trfase major Pgm1 (-18.0): gpmDB | homo | protein Phosphoglucomutase-1 (PGM 1)(EC 5.4.2.2)(Glucose phosphomutase 1) Source: UniProtKB/Swiss-Prot P38652 IPR005843 A-D-PHexomutase C IPR016066 A-D-PHexomutase CS IPR005841 A-D-PHexomutase N IPR005844 A-D-PHexomutase a/b/a-I IPR016055 A-D-PHexomutase a/b/a-I/II/III IPR005845 A-D-PHexomutase a/b/a-II IPR005846 A-D-PHexomutase a/b/a-III Idh2 (-16.1): gpmDB | homo | protein Isocitrate dehydrogenase [NADP], mitochondrial Precursor (IDH)(EC 1.1.1.42)(Oxalosuccinate decarboxylase)(NADP(+)-specific ICDH)(IDP)(ICD-M) Source: UniProtKB/Swiss-Prot P56574 IPR019818 IsoCit/isopropylmalate DH CS IPR001804 Isocitrate/isopropylmalate DH IPR004790 Isocitrate DH NADP-dep euk Uqcrc1 (-15.5): gpmDB | homo | protein Cytochrome b-c1 complex subunit 1, mitochondrial Precursor (Ubiquinol-cytochrome-c reductase complex core protein 1)(Core protein I)(Complex III subunit 1) Source: UniProtKB/Swiss-Prot Q68FY0 IPR011249 Metalloenz metal-bd IPR011765 Pept M16 N IPR007863 Peptidase M16 C Idh1 (-14.6): gpmDB | homo | protein Isocitrate dehydrogenase [NADP] cytoplasmic (IDH)(EC 1.1.1.42)(Cytosolic NADP-isocitrate dehydrogenase)(Oxalosuccinate decarboxylase)(NADP(+)-specific ICDH)(IDP) Source: UniProtKB/Swiss-Prot P41562 IPR019818 IsoCit/isopropylmalate DH CS IPR001804 Isocitrate/isopropylmalate DH IPR004790 Isocitrate DH NADP-dep euk Acat1 (-12.6): gpmDB | homo | protein Acetyl-CoA acetyltransferase, mitochondrial Precursor (EC 2.3.1.9)(Acetoacetyl-CoA thiolase) Source: UniProtKB/Swiss-Prot P17764 IPR002155 Thiolase IPR016039 Thiolase-like IPR020610 Thiolase AS IPR020617 Thiolase C IPR020613 Thiolase CS IPR020616 Thiolase N IPR020615 Thiolase acyl enz int AS ENSRNOP00000050636 (-7.1): gpmDB | homo | protein Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Precursor (EC 1.3.5.1)(Flavoprotein subunit of complex II)(Fp) Source: UniProtKB/Swiss-Prot Q920L2 IPR003953 FAD bind2 N IPR013027 FAD pyr nucl-diS OxRdtase IPR003952 FRD SDH FAD BS IPR015939 Fum Rdtase/Succ DH flav-like C IPR004112 Fum Rdtase/Succ DH flav C IPR011281 Succ DH flav su fwd IPR014006 Succ Dhase frdA Gneg Akr1b1-ps2 (-6.2): gpmDB | homo | protein Aldose reductase (AR)(EC 1.1.1.21)(Aldehyde reductase) Source: UniProtKB/Swiss-Prot P07943 IPR001395 Aldo/ket red IPR018170 Aldo/ket reductase CS IPR020471 Aldo/keto reductase sg ENSRNOP00000026185 (-5.1): gpmDB | homo | protein D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH). [Source: UniProt O08651] Source: 1.1.1.95 IPR006139 2 Hacid DH IPR006140 2hydac DH NAD bd IPR006236 PGDH
rno:00020	Citrate cycle (TCA cycle)	4.6	-4.1	7/0 proteins of 32 Aco2 (-218.4): gpmDB | homo | protein Aconitate hydratase, mitochondrial Precursor (Aconitase)(EC 4.2.1.3)(Citrate hydro-lyase) Source: UniProtKB/Swiss-Prot Q9ER34 IPR001030 Acoase/IPM deHydtase lsu aba IPR015928 Aconitase/3IPM dehydase swvl IPR000573 AconitaseA/IPMdHydase ssu swvl IPR018136 Aconitase 4Fe-4S BS IPR006248 Aconitase mito-like IPR020610 Thiolase AS Mdh2 (-96.3): gpmDB | homo | protein Malate dehydrogenase, mitochondrial Precursor (EC 1.1.1.37) Source: UniProtKB/Swiss-Prot P04636 IPR001557 L-lactate/malate DH IPR001236 Lactate/malate DH IPR015955 Lactate DH/Glyco Ohase 4 C IPR001252 Malate DH AS IPR010097 Malate DH NAD-dep euk/g-bac IPR016040 NAD(P)-bd dom Mdh1 (-65.8): gpmDB | homo | protein Malate dehydrogenase, cytoplasmic (EC 1.1.1.37)(Cytosolic malate dehydrogenase) Source: UniProtKB/Swiss-Prot O88989 IPR001557 L-lactate/malate DH IPR001236 Lactate/malate DH IPR015955 Lactate DH/Glyco Ohase 4 C IPR001252 Malate DH AS IPR011274 Malate DH NAD-dep euk IPR010945 Malate DH SF1 IPR016040 NAD(P)-bd dom Cs (-18.1): gpmDB | homo | protein Citrate synthase, mitochondrial Precursor (EC 2.3.3.1) Source: UniProtKB/Swiss-Prot Q8VHF5 IPR002020 Citrate synthase-like IPR016141 Citrate synthase-like core IPR019810 Citrate synthase AS IPR010109 Citrate synthase euk Idh2 (-16.1): gpmDB | homo | protein Isocitrate dehydrogenase [NADP], mitochondrial Precursor (IDH)(EC 1.1.1.42)(Oxalosuccinate decarboxylase)(NADP(+)-specific ICDH)(IDP)(ICD-M) Source: UniProtKB/Swiss-Prot P56574 IPR019818 IsoCit/isopropylmalate DH CS IPR001804 Isocitrate/isopropylmalate DH IPR004790 Isocitrate DH NADP-dep euk Idh1 (-14.6): gpmDB | homo | protein Isocitrate dehydrogenase [NADP] cytoplasmic (IDH)(EC 1.1.1.42)(Cytosolic NADP-isocitrate dehydrogenase)(Oxalosuccinate decarboxylase)(NADP(+)-specific ICDH)(IDP) Source: UniProtKB/Swiss-Prot P41562 IPR019818 IsoCit/isopropylmalate DH CS IPR001804 Isocitrate/isopropylmalate DH IPR004790 Isocitrate DH NADP-dep euk ENSRNOP00000050636 (-7.1): gpmDB | homo | protein Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Precursor (EC 1.3.5.1)(Flavoprotein subunit of complex II)(Fp) Source: UniProtKB/Swiss-Prot Q920L2 IPR003953 FAD bind2 N IPR013027 FAD pyr nucl-diS OxRdtase IPR003952 FRD SDH FAD BS IPR015939 Fum Rdtase/Succ DH flav-like C IPR004112 Fum Rdtase/Succ DH flav C IPR011281 Succ DH flav su fwd IPR014006 Succ Dhase frdA Gneg
rno:04530	Tight junction	5.9	-3.1	8/2 proteins of 127 Actb (-362.9): gpmDB | homo | protein Actin, cytoplasmic 1 (Beta-actin) [Contains Actin, cytoplasmic 1, N-terminally processed] Source: UniProtKB/Swiss-Prot P60711 IPR004000 Actin-like IPR020902 Actin/actin-like CS IPR004001 Actin CS RGD1563410 (-360.1): gpmDB | homo | protein Actin, cytoplasmic 2 (Gamma-actin) [Contains Actin, cytoplasmic 2, N-terminally processed] Source: UniProtKB/Swiss-Prot P63259 IPR004000 Actin-like IPR020902 Actin/actin-like CS IPR004001 Actin CS Actn4 (-218.6): gpmDB | homo | protein Alpha-actinin-4 (Non-muscle alpha-actinin 4)(F-actin cross-linking protein) Source: UniProtKB/Swiss-Prot Q9QXQ0 IPR001589 Actinin actin-bd CS IPR016146 Calponin-homology IPR001715 Calponin act bd IPR014837 EF-hand Ca insen IPR018247 EF HAND 1 IPR018249 EF HAND 2 IPR018248 EF Hand calmodulin IPR002048 EF hand Ca bd IPR018159 Spectrin/alpha-actinin IPR002017 Spectrin repeat ENSRNOP00000005990 (-104.5): gpmDB | homo | protein Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform)(Non-muscle alpha-actinin-1)(F-actin cross-linking protein) Source: UniProtKB/Swiss-Prot Q9Z1P2 IPR001589 Actinin actin-bd CS IPR016146 Calponin-homology IPR001715 Calponin act bd IPR014837 EF-hand Ca insen IPR018249 EF HAND 2 IPR018248 EF Hand calmodulin IPR002048 EF hand Ca bd IPR018159 Spectrin/alpha-actinin IPR002017 Spectrin repeat Myh9 (-42.5): gpmDB | homo | protein Myosin-9 (Myosin heavy chain 9)(Myosin heavy chain, non-muscle IIa)(Non-muscle myosin heavy chain IIa)(NMMHC II-a)(NMMHC-IIA)(Cellular myosin heavy chain, type A)(Non-muscle myosin heavy chain A)(NMMHC-A) Source: UniProtKB/Swiss-Prot Q62812 IPR000048 IQ CaM bd region IPR004009 Myosin N IPR001609 Myosin head IPR002928 Myosin tail IPR009053 Prefoldin IPR016137 Regulat G prot signal superfam IPR000533 Tropomyosin IPR006077 Vinculin/catenin IPR004174 gpW Gnai2 (-15.3): gpmDB | homo | protein Guanine nucleotide-binding protein G(i) subunit alpha-2 (Adenylate cyclase-inhibiting G alpha protein) Source: UniProtKB/Swiss-Prot P04897 IPR006688 ARF IPR002975 Fungi GproteinA IPR001019 Gprotein alph bd IPR000469 Gprotein alpha12 IPR001408 Gprotein alpha I IPR000367 Gprotein alpha S IPR001806 Ras GTPase ENSRNOP00000042382 (-14.2): gpmDB | homo | protein Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain)(Alpha-II spectrin)(Fodrin alpha chain) Source: UniProtKB/Swiss-Prot P16086 IPR014837 EF-hand Ca insen IPR018247 EF HAND 1 IPR018249 EF HAND 2 IPR018248 EF Hand calmodulin IPR002048 EF hand Ca bd IPR001452 SH3 domain IPR020473 SH3 region IPR018159 Spectrin/alpha-actinin IPR013315 Spectrin alpha SH3 IPR002017 Spectrin repeat ENSRNOP00000014609 (-7.6): gpmDB | homo | protein Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A subunit A isoform PR65-beta)(PP2A subunit A isoform R1-beta) Source: UniProtKB/Swiss-Prot Q4QQT4 IPR016024 ARM-type fold IPR000357 HEAT IPR021133 HEAT type 2 IPR001160 Peptidase M20C
rno:04520	Adherens junction	5.9	-2.5	5/1 proteins of 71 Actb (-362.9): gpmDB | homo | protein Actin, cytoplasmic 1 (Beta-actin) [Contains Actin, cytoplasmic 1, N-terminally processed] Source: UniProtKB/Swiss-Prot P60711 IPR004000 Actin-like IPR020902 Actin/actin-like CS IPR004001 Actin CS RGD1563410 (-360.1): gpmDB | homo | protein Actin, cytoplasmic 2 (Gamma-actin) [Contains Actin, cytoplasmic 2, N-terminally processed] Source: UniProtKB/Swiss-Prot P63259 IPR004000 Actin-like IPR020902 Actin/actin-like CS IPR004001 Actin CS Actn4 (-218.6): gpmDB | homo | protein Alpha-actinin-4 (Non-muscle alpha-actinin 4)(F-actin cross-linking protein) Source: UniProtKB/Swiss-Prot Q9QXQ0 IPR001589 Actinin actin-bd CS IPR016146 Calponin-homology IPR001715 Calponin act bd IPR014837 EF-hand Ca insen IPR018247 EF HAND 1 IPR018249 EF HAND 2 IPR018248 EF Hand calmodulin IPR002048 EF hand Ca bd IPR018159 Spectrin/alpha-actinin IPR002017 Spectrin repeat ENSRNOP00000005990 (-104.5): gpmDB | homo | protein Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform)(Non-muscle alpha-actinin-1)(F-actin cross-linking protein) Source: UniProtKB/Swiss-Prot Q9Z1P2 IPR001589 Actinin actin-bd CS IPR016146 Calponin-homology IPR001715 Calponin act bd IPR014837 EF-hand Ca insen IPR018249 EF HAND 2 IPR018248 EF Hand calmodulin IPR002048 EF hand Ca bd IPR018159 Spectrin/alpha-actinin IPR002017 Spectrin repeat Vcl (-23.9): gpmDB | homo | protein Vinculin (Metavinculin) Source: UniProtKB/Swiss-Prot P85972 IPR000694 PRO rich IPR017997 Vinculin IPR006077 Vinculin/catenin IPR000633 Vinculin CS
rno:00330	Arginine and proline metabolism	4.5	-2.5	5/0 proteins of 49 LOC314123 (-110.0): gpmDB | homo | protein Aspartate aminotransferase, mitochondrial Precursor (mAspAT)(EC 2.6.1.1)(Transaminase A)(Glutamate oxaloacetate transaminase 2)(Fatty acid-binding protein)(FABP-1)(Plasma membrane-associated fatty acid-binding protein)(FABPpm) Source: UniProtKB/Swiss-Prot P00507 IPR004839 Aminotrans I/II IPR000796 Asp trans IPR008120 Dense granule Gra7 protein IPR004838 NHTrfase class1 PyrdxlP-BS IPR015424 PyrdxlP-dep Trfase major Ckb (-100.1): gpmDB | homo | protein Creatine kinase B-type (EC 2.7.3.2)(Creatine kinase B chain)(B-CK) Source: UniProtKB/Swiss-Prot P07335 IPR000749 ATP-guanido PTrfase Aldh9a1 (-28.6): gpmDB | homo | protein 4-trimethylaminobutyraldehyde dehydrogenase (TMABADH)(EC 1.2.1.47)(Aldehyde dehydrogenase family 9 member A1)(EC 1.2.1.3) Source: UniProtKB/Swiss-Prot Q9JLJ3 Glud1 (-20.4): gpmDB | homo | protein Glutamate dehydrogenase 1, mitochondrial Precursor (GDH 1)(EC 1.4.1.3)(Memory-related gene 2 protein)(MRG-2) Source: UniProtKB/Swiss-Prot P10860 IPR006095 Glu/Leu/Phe/Val DH IPR006096 Glu/Leu/Phe/Val DH C IPR006097 Glu/Leu/Phe/Val DH dimer IPR016040 NAD(P)-bd dom Oat (-18.0): gpmDB | homo | protein Ornithine aminotransferase, mitochondrial Precursor (EC 2.6.1.13)(Ornithine--oxo-acid aminotransferase) [Source: UniProt P04182] Source: 2.6.1.13 IPR005814 Aminotrans 3 IPR013048 Meiotic Spo11 IPR010164 Orn aminotrans IPR015424 PyrdxlP-dep Trfase major
rno:00720	Reductive carboxylate cycle (CO2 fixation)	4.6	-2.5	5/0 proteins of 12 Aco2 (-218.4): gpmDB | homo | protein Aconitate hydratase, mitochondrial Precursor (Aconitase)(EC 4.2.1.3)(Citrate hydro-lyase) Source: UniProtKB/Swiss-Prot Q9ER34 IPR001030 Acoase/IPM deHydtase lsu aba IPR015928 Aconitase/3IPM dehydase swvl IPR000573 AconitaseA/IPMdHydase ssu swvl IPR018136 Aconitase 4Fe-4S BS IPR006248 Aconitase mito-like IPR020610 Thiolase AS Mdh2 (-96.3): gpmDB | homo | protein Malate dehydrogenase, mitochondrial Precursor (EC 1.1.1.37) Source: UniProtKB/Swiss-Prot P04636 IPR001557 L-lactate/malate DH IPR001236 Lactate/malate DH IPR015955 Lactate DH/Glyco Ohase 4 C IPR001252 Malate DH AS IPR010097 Malate DH NAD-dep euk/g-bac IPR016040 NAD(P)-bd dom Mdh1 (-65.8): gpmDB | homo | protein Malate dehydrogenase, cytoplasmic (EC 1.1.1.37)(Cytosolic malate dehydrogenase) Source: UniProtKB/Swiss-Prot O88989 IPR001557 L-lactate/malate DH IPR001236 Lactate/malate DH IPR015955 Lactate DH/Glyco Ohase 4 C IPR001252 Malate DH AS IPR011274 Malate DH NAD-dep euk IPR010945 Malate DH SF1 IPR016040 NAD(P)-bd dom Idh2 (-16.1): gpmDB | homo | protein Isocitrate dehydrogenase [NADP], mitochondrial Precursor (IDH)(EC 1.1.1.42)(Oxalosuccinate decarboxylase)(NADP(+)-specific ICDH)(IDP)(ICD-M) Source: UniProtKB/Swiss-Prot P56574 IPR019818 IsoCit/isopropylmalate DH CS IPR001804 Isocitrate/isopropylmalate DH IPR004790 Isocitrate DH NADP-dep euk Idh1 (-14.6): gpmDB | homo | protein Isocitrate dehydrogenase [NADP] cytoplasmic (IDH)(EC 1.1.1.42)(Cytosolic NADP-isocitrate dehydrogenase)(Oxalosuccinate decarboxylase)(NADP(+)-specific ICDH)(IDP) Source: UniProtKB/Swiss-Prot P41562 IPR019818 IsoCit/isopropylmalate DH CS IPR001804 Isocitrate/isopropylmalate DH IPR004790 Isocitrate DH NADP-dep euk
rno:04670	Leukocyte transendothelial migration	5.9	-2.5	7/2 proteins of 112 Actb (-362.9): gpmDB | homo | protein Actin, cytoplasmic 1 (Beta-actin) [Contains Actin, cytoplasmic 1, N-terminally processed] Source: UniProtKB/Swiss-Prot P60711 IPR004000 Actin-like IPR020902 Actin/actin-like CS IPR004001 Actin CS RGD1563410 (-360.1): gpmDB | homo | protein Actin, cytoplasmic 2 (Gamma-actin) [Contains Actin, cytoplasmic 2, N-terminally processed] Source: UniProtKB/Swiss-Prot P63259 IPR004000 Actin-like IPR020902 Actin/actin-like CS IPR004001 Actin CS Actn4 (-218.6): gpmDB | homo | protein Alpha-actinin-4 (Non-muscle alpha-actinin 4)(F-actin cross-linking protein) Source: UniProtKB/Swiss-Prot Q9QXQ0 IPR001589 Actinin actin-bd CS IPR016146 Calponin-homology IPR001715 Calponin act bd IPR014837 EF-hand Ca insen IPR018247 EF HAND 1 IPR018249 EF HAND 2 IPR018248 EF Hand calmodulin IPR002048 EF hand Ca bd IPR018159 Spectrin/alpha-actinin IPR002017 Spectrin repeat ENSRNOP00000025122 (-124.8): gpmDB | homo | protein Ezrin (p81)(Cytovillin)(Villin-2) Source: UniProtKB/Swiss-Prot P31977 IPR019749 Band 41 domain IPR019750 Band 41 sg IPR011174 ERM IPR011259 ERM C IPR000798 Ez/rad/moesin IPR019747 FERM CS IPR019748 FERM central IPR000299 FERM domain IPR008954 Moesin IPR000533 Tropomyosin ENSRNOP00000005990 (-104.5): gpmDB | homo | protein Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform)(Non-muscle alpha-actinin-1)(F-actin cross-linking protein) Source: UniProtKB/Swiss-Prot Q9Z1P2 IPR001589 Actinin actin-bd CS IPR016146 Calponin-homology IPR001715 Calponin act bd IPR014837 EF-hand Ca insen IPR018249 EF HAND 2 IPR018248 EF Hand calmodulin IPR002048 EF hand Ca bd IPR018159 Spectrin/alpha-actinin IPR002017 Spectrin repeat Vcl (-23.9): gpmDB | homo | protein Vinculin (Metavinculin) Source: UniProtKB/Swiss-Prot P85972 IPR000694 PRO rich IPR017997 Vinculin IPR006077 Vinculin/catenin IPR000633 Vinculin CS Gnai2 (-15.3): gpmDB | homo | protein Guanine nucleotide-binding protein G(i) subunit alpha-2 (Adenylate cyclase-inhibiting G alpha protein) Source: UniProtKB/Swiss-Prot P04897 IPR006688 ARF IPR002975 Fungi GproteinA IPR001019 Gprotein alph bd IPR000469 Gprotein alpha12 IPR001408 Gprotein alpha I IPR000367 Gprotein alpha S IPR001806 Ras GTPase
rno:04810	Regulation of actin cytoskeleton	6.0	-2.3	10/4 proteins of 213 Actb (-362.9): gpmDB | homo | protein Actin, cytoplasmic 1 (Beta-actin) [Contains Actin, cytoplasmic 1, N-terminally processed] Source: UniProtKB/Swiss-Prot P60711 IPR004000 Actin-like IPR020902 Actin/actin-like CS IPR004001 Actin CS RGD1563410 (-360.1): gpmDB | homo | protein Actin, cytoplasmic 2 (Gamma-actin) [Contains Actin, cytoplasmic 2, N-terminally processed] Source: UniProtKB/Swiss-Prot P63259 IPR004000 Actin-like IPR020902 Actin/actin-like CS IPR004001 Actin CS Actn4 (-218.6): gpmDB | homo | protein Alpha-actinin-4 (Non-muscle alpha-actinin 4)(F-actin cross-linking protein) Source: UniProtKB/Swiss-Prot Q9QXQ0 IPR001589 Actinin actin-bd CS IPR016146 Calponin-homology IPR001715 Calponin act bd IPR014837 EF-hand Ca insen IPR018247 EF HAND 1 IPR018249 EF HAND 2 IPR018248 EF Hand calmodulin IPR002048 EF hand Ca bd IPR018159 Spectrin/alpha-actinin IPR002017 Spectrin repeat ENSRNOP00000035840 (-147.3): gpmDB | homo | protein radixin [Source:RefSeq peptide;Acc:NP_001005889] IPR013992 Adenylate cyclase-assoc CAP N IPR019749 Band 41 domain IPR019750 Band 41 sg IPR011174 ERM IPR011259 ERM C IPR000798 Ez/rad/moesin IPR019747 FERM CS IPR019748 FERM central IPR000299 FERM domain IPR008954 Moesin ENSRNOP00000025122 (-124.8): gpmDB | homo | protein Ezrin (p81)(Cytovillin)(Villin-2) Source: UniProtKB/Swiss-Prot P31977 IPR019749 Band 41 domain IPR019750 Band 41 sg IPR011174 ERM IPR011259 ERM C IPR000798 Ez/rad/moesin IPR019747 FERM CS IPR019748 FERM central IPR000299 FERM domain IPR008954 Moesin IPR000533 Tropomyosin ENSRNOP00000025857 (-124.1): gpmDB | homo | protein Gelsolin Precursor (Actin-depolymerizing factor)(ADF)(Brevin) [Source: UniProt Q68FP1] IPR007122 Gelsolin IPR007123 Gelsoln ENSRNOP00000005990 (-104.5): gpmDB | homo | protein Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform)(Non-muscle alpha-actinin-1)(F-actin cross-linking protein) Source: UniProtKB/Swiss-Prot Q9Z1P2 IPR001589 Actinin actin-bd CS IPR016146 Calponin-homology IPR001715 Calponin act bd IPR014837 EF-hand Ca insen IPR018249 EF HAND 2 IPR018248 EF Hand calmodulin IPR002048 EF hand Ca bd IPR018159 Spectrin/alpha-actinin IPR002017 Spectrin repeat Myh9 (-42.5): gpmDB | homo | protein Myosin-9 (Myosin heavy chain 9)(Myosin heavy chain, non-muscle IIa)(Non-muscle myosin heavy chain IIa)(NMMHC II-a)(NMMHC-IIA)(Cellular myosin heavy chain, type A)(Non-muscle myosin heavy chain A)(NMMHC-A) Source: UniProtKB/Swiss-Prot Q62812 IPR000048 IQ CaM bd region IPR004009 Myosin N IPR001609 Myosin head IPR002928 Myosin tail IPR009053 Prefoldin IPR016137 Regulat G prot signal superfam IPR000533 Tropomyosin IPR006077 Vinculin/catenin IPR004174 gpW Vcl (-23.9): gpmDB | homo | protein Vinculin (Metavinculin) Source: UniProtKB/Swiss-Prot P85972 IPR000694 PRO rich IPR017997 Vinculin IPR006077 Vinculin/catenin IPR000633 Vinculin CS ENSRNOP00000028041 (-15.9): gpmDB | homo | protein Cofilin-1 (Cofilin, non-muscle isoform) Source: UniProtKB/Swiss-Prot P45592 IPR017904 ADF/Cofilin/Destrin IPR002108 Actin-bd cofilin/tropomyosin
rno:04260	Cardiac muscle contraction	4.3	-1.8	4/1 proteins of 96 Atp1a3 (-126.6): gpmDB | homo | protein Sodium/potassium-transporting ATPase subunit alpha-3 (Na(+)/K(+) ATPase alpha-3 subunit)(EC 3.6.3.9)(Sodium pump subunit alpha-3)(Na(+)/K(+) ATPase alpha(III) subunit) Source: UniProtKB/Swiss-Prot P06687 IPR008250 ATPase P-typ ATPase-assoc-dom IPR000695 ATPase P-typ H-transp IPR018303 ATPase P-typ P site IPR005775 ATPase P-typ cation-ex asu euk IPR006069 ATPase P-typ cation-exchng asu IPR006068 ATPase P-typ cation-transptr C IPR004014 ATPase P-typ cation-transptr N IPR001757 ATPase P-typ ion-transptr IPR005834 Dehalogen-like hydro ENSRNOP00000001738 (-30.2): gpmDB | homo | protein Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SR Ca(2+)-ATPase 2)(SERCA2)(EC 3.6.3.8)(Calcium pump 2)(Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform)(Endoplasmic reticulum class 1/2 Ca(2+) ATPase) Source: UniProtKB/Swiss-Prot P11507 IPR008250 ATPase P-typ ATPase-assoc-dom IPR005782 ATPase P-typ Ca-transp IPR000695 ATPase P-typ H-transp IPR018303 ATPase P-typ P site IPR006069 ATPase P-typ cation-exchng asu IPR006068 ATPase P-typ cation-transptr C IPR004014 ATPase P-typ cation-transptr N IPR001757 ATPase P-typ ion-transptr IPR005834 Dehalogen-like hydro Atp1b1 (-29.0): gpmDB | homo | protein Sodium/potassium-transporting ATPase subunit beta-1 (Sodium/potassium-dependent ATPase subunit beta-1) Source: UniProtKB/Swiss-Prot P07340 IPR000402 ATPase P-typ cation-exchng bsu Uqcrc1 (-15.5): gpmDB | homo | protein Cytochrome b-c1 complex subunit 1, mitochondrial Precursor (Ubiquinol-cytochrome-c reductase complex core protein 1)(Core protein I)(Complex III subunit 1) Source: UniProtKB/Swiss-Prot Q68FY0 IPR011249 Metalloenz metal-bd IPR011765 Pept M16 N IPR007863 Peptidase M16 C
rno:00630	Glyoxylate and dicarboxylate metabolism	4.6	-1.8	4/0 proteins of 10 Aco2 (-218.4): gpmDB | homo | protein Aconitate hydratase, mitochondrial Precursor (Aconitase)(EC 4.2.1.3)(Citrate hydro-lyase) Source: UniProtKB/Swiss-Prot Q9ER34 IPR001030 Acoase/IPM deHydtase lsu aba IPR015928 Aconitase/3IPM dehydase swvl IPR000573 AconitaseA/IPMdHydase ssu swvl IPR018136 Aconitase 4Fe-4S BS IPR006248 Aconitase mito-like IPR020610 Thiolase AS Mdh2 (-96.3): gpmDB | homo | protein Malate dehydrogenase, mitochondrial Precursor (EC 1.1.1.37) Source: UniProtKB/Swiss-Prot P04636 IPR001557 L-lactate/malate DH IPR001236 Lactate/malate DH IPR015955 Lactate DH/Glyco Ohase 4 C IPR001252 Malate DH AS IPR010097 Malate DH NAD-dep euk/g-bac IPR016040 NAD(P)-bd dom Mdh1 (-65.8): gpmDB | homo | protein Malate dehydrogenase, cytoplasmic (EC 1.1.1.37)(Cytosolic malate dehydrogenase) Source: UniProtKB/Swiss-Prot O88989 IPR001557 L-lactate/malate DH IPR001236 Lactate/malate DH IPR015955 Lactate DH/Glyco Ohase 4 C IPR001252 Malate DH AS IPR011274 Malate DH NAD-dep euk IPR010945 Malate DH SF1 IPR016040 NAD(P)-bd dom Cs (-18.1): gpmDB | homo | protein Citrate synthase, mitochondrial Precursor (EC 2.3.3.1) Source: UniProtKB/Swiss-Prot Q8VHF5 IPR002020 Citrate synthase-like IPR016141 Citrate synthase-like core IPR019810 Citrate synthase AS IPR010109 Citrate synthase euk
rno:00640	Propanoate metabolism	4.4	-1.8	4/0 proteins of 35 Ldhb (-94.5): gpmDB | homo | protein L-lactate dehydrogenase B chain (LDH-B)(EC 1.1.1.27)(LDH heart subunit)(LDH-H) Source: UniProtKB/Swiss-Prot P42123 IPR001557 L-lactate/malate DH IPR011304 L-lactate DH IPR018177 L-lactate DH AS IPR001236 Lactate/malate DH IPR015955 Lactate DH/Glyco Ohase 4 C IPR016040 NAD(P)-bd dom IPR001806 Ras GTPase ENSRNOP00000012585 (-41.6): gpmDB | homo | protein no description available IPR001557 L LDH MDH IPR011304 L LDH NAD IPR001236 Lactate/malate DH IPR015955 Lactate DH/Glyco hydro 4 C IPR001806 Ras trnsfrmng Aldh9a1 (-28.6): gpmDB | homo | protein 4-trimethylaminobutyraldehyde dehydrogenase (TMABADH)(EC 1.2.1.47)(Aldehyde dehydrogenase family 9 member A1)(EC 1.2.1.3) Source: UniProtKB/Swiss-Prot Q9JLJ3 Acat1 (-12.6): gpmDB | homo | protein Acetyl-CoA acetyltransferase, mitochondrial Precursor (EC 2.3.1.9)(Acetoacetyl-CoA thiolase) Source: UniProtKB/Swiss-Prot P17764 IPR002155 Thiolase IPR016039 Thiolase-like IPR020610 Thiolase AS IPR020617 Thiolase C IPR020613 Thiolase CS IPR020616 Thiolase N IPR020615 Thiolase acyl enz int AS
rno:00030	Pentose phosphate pathway	4.1	-1.8	4/0 proteins of 27 Tkt (-52.6): gpmDB | homo | protein Transketolase (TK)(EC 2.2.1.1) Source: UniProtKB/Swiss-Prot P50137 IPR005476 Transketo C IPR009014 Transketo C/Pyr-ferredox oxred IPR005474 Transketo N IPR005475 Transketolase-like Pyr-bd IPR020826 Transketolase BS LOC365784 (-42.7): gpmDB | homo | protein Fructose-bisphosphate aldolase A (EC 4.1.2.13)(Muscle-type aldolase) Source: UniProtKB/Swiss-Prot P05065 IPR000741 Aldolase I Gpi (-32.3): gpmDB | homo | protein Glucose-6-phosphate isomerase (GPI)(EC 5.3.1.9)(Phosphoglucose isomerase)(PGI)(Phosphohexose isomerase)(PHI)(Autocrine motility factor)(AMF)(Neuroleukin)(NLK) Source: UniProtKB/Swiss-Prot Q6P6V0 IPR001672 G6P Isomerase IPR018189 Phosphoglucose isomerase CS Pgm1 (-18.0): gpmDB | homo | protein Phosphoglucomutase-1 (PGM 1)(EC 5.4.2.2)(Glucose phosphomutase 1) Source: UniProtKB/Swiss-Prot P38652 IPR005843 A-D-PHexomutase C IPR016066 A-D-PHexomutase CS IPR005841 A-D-PHexomutase N IPR005844 A-D-PHexomutase a/b/a-I IPR016055 A-D-PHexomutase a/b/a-I/II/III IPR005845 A-D-PHexomutase a/b/a-II IPR005846 A-D-PHexomutase a/b/a-III
rno:00270	Cysteine and methionine metabolism	4.5	-1.8	4/0 proteins of 32 LOC314123 (-110.0): gpmDB | homo | protein Aspartate aminotransferase, mitochondrial Precursor (mAspAT)(EC 2.6.1.1)(Transaminase A)(Glutamate oxaloacetate transaminase 2)(Fatty acid-binding protein)(FABP-1)(Plasma membrane-associated fatty acid-binding protein)(FABPpm) Source: UniProtKB/Swiss-Prot P00507 IPR004839 Aminotrans I/II IPR000796 Asp trans IPR008120 Dense granule Gra7 protein IPR004838 NHTrfase class1 PyrdxlP-BS IPR015424 PyrdxlP-dep Trfase major Ldhb (-94.5): gpmDB | homo | protein L-lactate dehydrogenase B chain (LDH-B)(EC 1.1.1.27)(LDH heart subunit)(LDH-H) Source: UniProtKB/Swiss-Prot P42123 IPR001557 L-lactate/malate DH IPR011304 L-lactate DH IPR018177 L-lactate DH AS IPR001236 Lactate/malate DH IPR015955 Lactate DH/Glyco Ohase 4 C IPR016040 NAD(P)-bd dom IPR001806 Ras GTPase ENSRNOP00000012585 (-41.6): gpmDB | homo | protein no description available IPR001557 L LDH MDH IPR011304 L LDH NAD IPR001236 Lactate/malate DH IPR015955 Lactate DH/Glyco hydro 4 C IPR001806 Ras trnsfrmng LOC500370 (-18.5): gpmDB | homo | protein Adenosylhomocysteinase (AdoHcyase)(EC 3.3.1.1)(S-adenosyl-L-homocysteine hydrolase) Source: UniProtKB/Swiss-Prot P10760 IPR015878 Ado hCys hydrolase NAD-bd IPR000043 S-Ado-L-homoCys hydrolase IPR020082 S-Ado-L-homoCys hydrolase CS
rno:04510	Focal adhesion	5.9	-1.7	7/3 proteins of 189 Actb (-362.9): gpmDB | homo | protein Actin, cytoplasmic 1 (Beta-actin) [Contains Actin, cytoplasmic 1, N-terminally processed] Source: UniProtKB/Swiss-Prot P60711 IPR004000 Actin-like IPR020902 Actin/actin-like CS IPR004001 Actin CS RGD1563410 (-360.1): gpmDB | homo | protein Actin, cytoplasmic 2 (Gamma-actin) [Contains Actin, cytoplasmic 2, N-terminally processed] Source: UniProtKB/Swiss-Prot P63259 IPR004000 Actin-like IPR020902 Actin/actin-like CS IPR004001 Actin CS Actn4 (-218.6): gpmDB | homo | protein Alpha-actinin-4 (Non-muscle alpha-actinin 4)(F-actin cross-linking protein) Source: UniProtKB/Swiss-Prot Q9QXQ0 IPR001589 Actinin actin-bd CS IPR016146 Calponin-homology IPR001715 Calponin act bd IPR014837 EF-hand Ca insen IPR018247 EF HAND 1 IPR018249 EF HAND 2 IPR018248 EF Hand calmodulin IPR002048 EF hand Ca bd IPR018159 Spectrin/alpha-actinin IPR002017 Spectrin repeat ENSRNOP00000005990 (-104.5): gpmDB | homo | protein Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform)(Non-muscle alpha-actinin-1)(F-actin cross-linking protein) Source: UniProtKB/Swiss-Prot Q9Z1P2 IPR001589 Actinin actin-bd CS IPR016146 Calponin-homology IPR001715 Calponin act bd IPR014837 EF-hand Ca insen IPR018249 EF HAND 2 IPR018248 EF Hand calmodulin IPR002048 EF hand Ca bd IPR018159 Spectrin/alpha-actinin IPR002017 Spectrin repeat Vcl (-23.9): gpmDB | homo | protein Vinculin (Metavinculin) Source: UniProtKB/Swiss-Prot P85972 IPR000694 PRO rich IPR017997 Vinculin IPR006077 Vinculin/catenin IPR000633 Vinculin CS Col3a1 (-8.8): gpmDB | homo | protein Collagen alpha-1(III) chain Precursor Source: UniProtKB/Swiss-Prot P13941 IPR008160 Collagen IPR000885 Fib collagen C IPR002181 Fibrinogen a/b/g C IPR000694 PRO rich IPR006552 VWC out IPR001007 VWF C Col5a1 (-4.3): gpmDB | homo | protein Collagen alpha-1(V) chain Precursor Source: UniProtKB/Swiss-Prot Q9JI03 IPR008160 Collagen IPR008985 ConA-like lec gl IPR000885 Fib collagen C IPR002181 Fibrinogen a/b/g C IPR001791 Laminin G IPR012680 Laminin G 2 IPR003129 Laminin G thrombospondin N IPR000694 PRO rich
rno:04020	Calcium signaling pathway	4.7	-1.7	7/3 proteins of 172 Slc25a4 (-62.4): gpmDB | homo | protein ADP/ATP translocase 1 (Adenine nucleotide translocator 1)(ANT 1)(ADP,ATP carrier protein 1)(Solute carrier family 25 member 4) Source: UniProtKB/Swiss-Prot Q05962 IPR002113 Aden trnslctor IPR002167 Graves DC IPR002067 Mit carrier IPR002030 Mit uncoupling IPR001993 Mitochondria substrate carrier IPR018108 Mitochondrial sb/sol carrier RGD1566161 (-56.7): gpmDB | homo | protein Voltage-dependent anion-selective channel protein 1 (VDAC-1)(rVDAC1)(Outer mitochondrial membrane protein porin 1) Source: UniProtKB/Swiss-Prot Q9Z2L0 IPR001925 Porin Euk Vdac2 (-37.7): gpmDB | homo | protein Voltage-dependent anion-selective channel protein 2 (VDAC-2)(Outer mitochondrial membrane protein porin 2)(B36-VDAC) [Source: UniProt P81155] IPR001925 Porin Euk Slc25a5 (-37.6): gpmDB | homo | protein ADP/ATP translocase 2 (Adenine nucleotide translocator 2)(ANT 2)(ADP,ATP carrier protein 2)(Solute carrier family 25 member 5) Source: UniProtKB/Swiss-Prot Q09073 IPR002113 Aden trnslctor IPR002067 Mit carrier IPR002030 Mit uncoupling IPR001993 Mitochondria substrate carrier IPR018108 Mitochondrial sb/sol carrier ENSRNOP00000001738 (-30.2): gpmDB | homo | protein Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SR Ca(2+)-ATPase 2)(SERCA2)(EC 3.6.3.8)(Calcium pump 2)(Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform)(Endoplasmic reticulum class 1/2 Ca(2+) ATPase) Source: UniProtKB/Swiss-Prot P11507 IPR008250 ATPase P-typ ATPase-assoc-dom IPR005782 ATPase P-typ Ca-transp IPR000695 ATPase P-typ H-transp IPR018303 ATPase P-typ P site IPR006069 ATPase P-typ cation-exchng asu IPR006068 ATPase P-typ cation-transptr C IPR004014 ATPase P-typ cation-transptr N IPR001757 ATPase P-typ ion-transptr IPR005834 Dehalogen-like hydro ENSRNOP00000005491 (-29.9): gpmDB | homo | protein Plasma membrane calcium-transporting ATPase 1 (PMCA1)(EC 3.6.3.8)(Plasma membrane calcium ATPase isoform 1)(Plasma membrane calcium pump isoform 1) Source: UniProtKB/Swiss-Prot P11505 IPR008250 ATPase P-typ ATPase-assoc-dom IPR006408 ATPase P-typ Ca-transp PMCA IPR018303 ATPase P-typ P site IPR006068 ATPase P-typ cation-transptr C IPR004014 ATPase P-typ cation-transptr N IPR001757 ATPase P-typ ion-transptr IPR005834 Dehalogen-like hydro ENSRNOP00000002042 (-14.1): gpmDB | homo | protein Sodium/calcium exchanger 2 precursor (Na(+)/Ca(2+)-exchange protein 2). [Source: UniProt P48768] IPR003644 Calx beta IPR004837 NaCa Exmemb IPR004836 Na Ca Ex
rno:00190	Oxidative phosphorylation	4.7	-1.3	6/3 proteins of 165 Atp5a1 (-179.1): gpmDB | homo | protein ATP synthase subunit alpha, mitochondrial Precursor Source: UniProtKB/Swiss-Prot P15999 IPR005294 ATPase F1-cplx asu IPR018118 ATPase F1/A1-cplx a/bsu N IPR000793 ATPase F1/V1/A1-cplx a/bsu C IPR004100 ATPase F1/V1/A1-cplx a/bsu N IPR020003 ATPase F1/V1/A1 a/bsu AS IPR000194 ATPase F1/V1/A1 a/bsu nucl-bd LOC365654 (-163.3): gpmDB | homo | protein ATP synthase subunit beta, mitochondrial Precursor (EC 3.6.3.14) Source: UniProtKB/Swiss-Prot P10719 IPR003593 ATPase AAA+ core IPR005722 ATPase F1-cplx bsu IPR018118 ATPase F1/A1-cplx a/bsu N IPR000793 ATPase F1/V1/A1-cplx a/bsu C IPR004100 ATPase F1/V1/A1-cplx a/bsu N IPR020003 ATPase F1/V1/A1 a/bsu AS IPR000194 ATPase F1/V1/A1 a/bsu nucl-bd Ndufs1 (-24.5): gpmDB | homo | protein NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial Precursor (EC 1.6.5.3)(EC 1.6.99.3) [Source: UniProt Q66HF1] Source: 1.6.5.3 IPR001041 Ferredoxin IPR006656 Mopterin OxRdtase IPR000283 NADH UbQ OxRdtase 75KDa su CS IPR010228 NADH UbQ OxRdtase Gsu IPR015405 NuoG C Atp6v1b2 (-20.5): gpmDB | homo | protein V-type proton ATPase subunit B, brain isoform (V-ATPase subunit B 2)(Vacuolar proton pump subunit B 2)(Endomembrane proton pump 58 kDa subunit) Source: UniProtKB/Swiss-Prot P62815 IPR000793 ATPase F1/V1/A1-cplx a/bsu C IPR004100 ATPase F1/V1/A1-cplx a/bsu N IPR020003 ATPase F1/V1/A1 a/bsu AS IPR000194 ATPase F1/V1/A1 a/bsu nucl-bd IPR005723 ATPase V1-cplx bsu Uqcrc1 (-15.5): gpmDB | homo | protein Cytochrome b-c1 complex subunit 1, mitochondrial Precursor (Ubiquinol-cytochrome-c reductase complex core protein 1)(Core protein I)(Complex III subunit 1) Source: UniProtKB/Swiss-Prot Q68FY0 IPR011249 Metalloenz metal-bd IPR011765 Pept M16 N IPR007863 Peptidase M16 C ENSRNOP00000050636 (-7.1): gpmDB | homo | protein Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Precursor (EC 1.3.5.1)(Flavoprotein subunit of complex II)(Fp) Source: UniProtKB/Swiss-Prot Q920L2 IPR003953 FAD bind2 N IPR013027 FAD pyr nucl-diS OxRdtase IPR003952 FRD SDH FAD BS IPR015939 Fum Rdtase/Succ DH flav-like C IPR004112 Fum Rdtase/Succ DH flav C IPR011281 Succ DH flav su fwd IPR014006 Succ Dhase frdA Gneg
rno:00051	Fructose and mannose metabolism	3.9	-1.2	3/0 proteins of 34 LOC365784 (-42.7): gpmDB | homo | protein Fructose-bisphosphate aldolase A (EC 4.1.2.13)(Muscle-type aldolase) Source: UniProtKB/Swiss-Prot P05065 IPR000741 Aldolase I ENSRNOP00000039702 (-25.2): gpmDB | homo | protein triosephosphate isomerase Source: RefSeq_peptide NP_001028244 IPR000652 Triophos ismrse Akr1b1-ps2 (-6.2): gpmDB | homo | protein Aldose reductase (AR)(EC 1.1.1.21)(Aldehyde reductase) Source: UniProtKB/Swiss-Prot P07943 IPR001395 Aldo/ket red IPR018170 Aldo/ket reductase CS IPR020471 Aldo/keto reductase sg
rno:00310	Lysine degradation	3.8	-1.2	3/0 proteins of 40 Aldh9a1 (-28.6): gpmDB | homo | protein 4-trimethylaminobutyraldehyde dehydrogenase (TMABADH)(EC 1.2.1.47)(Aldehyde dehydrogenase family 9 member A1)(EC 1.2.1.3) Source: UniProtKB/Swiss-Prot Q9JLJ3 Acat1 (-12.6): gpmDB | homo | protein Acetyl-CoA acetyltransferase, mitochondrial Precursor (EC 2.3.1.9)(Acetoacetyl-CoA thiolase) Source: UniProtKB/Swiss-Prot P17764 IPR002155 Thiolase IPR016039 Thiolase-like IPR020610 Thiolase AS IPR020617 Thiolase C IPR020613 Thiolase CS IPR020616 Thiolase N IPR020615 Thiolase acyl enz int AS Plod2 (-4.4): gpmDB | homo | protein Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 precursor (EC 1.14.11.4) (Lysyl hydroxylase 2) (LH2). [Source: UniProt Q811A3] Source: 1.14.11.4 IPR005123 2OG-FeII Oase IPR006620 Pro 4 hyd alph IPR001006 Procol lys dOase IPR002160 Prot inh Kunz-lg
rno:00380	Tryptophan metabolism	3.9	-1.2	3/0 proteins of 43 Cat (-35.7): gpmDB | homo | protein Catalase (EC 1.11.1.6) Source: UniProtKB/Swiss-Prot P04762 IPR002226 Catalase IPR020835 Catalase-like haem-dep IPR018028 Catalase rel subgroup Aldh9a1 (-28.6): gpmDB | homo | protein 4-trimethylaminobutyraldehyde dehydrogenase (TMABADH)(EC 1.2.1.47)(Aldehyde dehydrogenase family 9 member A1)(EC 1.2.1.3) Source: UniProtKB/Swiss-Prot Q9JLJ3 Acat1 (-12.6): gpmDB | homo | protein Acetyl-CoA acetyltransferase, mitochondrial Precursor (EC 2.3.1.9)(Acetoacetyl-CoA thiolase) Source: UniProtKB/Swiss-Prot P17764 IPR002155 Thiolase IPR016039 Thiolase-like IPR020610 Thiolase AS IPR020617 Thiolase C IPR020613 Thiolase CS IPR020616 Thiolase N IPR020615 Thiolase acyl enz int AS
rno:00650	Butanoate metabolism	4.0	-1.2	3/0 proteins of 31 ENSRNOP00000020798 (-28.6): gpmDB | homo | protein Succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial Precursor (EC 2.8.3.5)(3-oxoacid-CoA transferase 1)(Somatic-type succinyl CoA:3-oxoacid CoA-transferase)(Scot-S) [Source: UniProt B2GV06] Source: 2.8.3.5 IPR012792 3-oxoacid CoA-transf A IPR014388 3-oxoacid CoA-transferase IPR004165 CoA trans IPR004164 CoA transf AS IPR004163 CoA transf BS Aldh9a1 (-28.6): gpmDB | homo | protein 4-trimethylaminobutyraldehyde dehydrogenase (TMABADH)(EC 1.2.1.47)(Aldehyde dehydrogenase family 9 member A1)(EC 1.2.1.3) Source: UniProtKB/Swiss-Prot Q9JLJ3 Acat1 (-12.6): gpmDB | homo | protein Acetyl-CoA acetyltransferase, mitochondrial Precursor (EC 2.3.1.9)(Acetoacetyl-CoA thiolase) Source: UniProtKB/Swiss-Prot P17764 IPR002155 Thiolase IPR016039 Thiolase-like IPR020610 Thiolase AS IPR020617 Thiolase C IPR020613 Thiolase CS IPR020616 Thiolase N IPR020615 Thiolase acyl enz int AS
rno:04730	Long-term depression	3.5	-1.2	3/1 proteins of 66 Gnai2 (-15.3): gpmDB | homo | protein Guanine nucleotide-binding protein G(i) subunit alpha-2 (Adenylate cyclase-inhibiting G alpha protein) Source: UniProtKB/Swiss-Prot P04897 IPR006688 ARF IPR002975 Fungi GproteinA IPR001019 Gprotein alph bd IPR000469 Gprotein alpha12 IPR001408 Gprotein alpha I IPR000367 Gprotein alpha S IPR001806 Ras GTPase Gnao1 (-7.7): gpmDB | homo | protein Guanine nucleotide-binding protein G(o) subunit alpha Source: UniProtKB/Swiss-Prot P59215 IPR006688 ARF IPR002975 Fungi GproteinA IPR001019 Gprotein alph bd IPR001408 Gprotein alpha I IPR001806 Ras GTPase ENSRNOP00000014609 (-7.6): gpmDB | homo | protein Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A subunit A isoform PR65-beta)(PP2A subunit A isoform R1-beta) Source: UniProtKB/Swiss-Prot Q4QQT4 IPR016024 ARM-type fold IPR000357 HEAT IPR021133 HEAT type 2 IPR001160 Peptidase M20C
rno:00280	Valine, leucine and isoleucine degradation	4.0	-1.2	3/0 proteins of 46 ENSRNOP00000020798 (-28.6): gpmDB | homo | protein Succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial Precursor (EC 2.8.3.5)(3-oxoacid-CoA transferase 1)(Somatic-type succinyl CoA:3-oxoacid CoA-transferase)(Scot-S) [Source: UniProt B2GV06] Source: 2.8.3.5 IPR012792 3-oxoacid CoA-transf A IPR014388 3-oxoacid CoA-transferase IPR004165 CoA trans IPR004164 CoA transf AS IPR004163 CoA transf BS Aldh9a1 (-28.6): gpmDB | homo | protein 4-trimethylaminobutyraldehyde dehydrogenase (TMABADH)(EC 1.2.1.47)(Aldehyde dehydrogenase family 9 member A1)(EC 1.2.1.3) Source: UniProtKB/Swiss-Prot Q9JLJ3 Acat1 (-12.6): gpmDB | homo | protein Acetyl-CoA acetyltransferase, mitochondrial Precursor (EC 2.3.1.9)(Acetoacetyl-CoA thiolase) Source: UniProtKB/Swiss-Prot P17764 IPR002155 Thiolase IPR016039 Thiolase-like IPR020610 Thiolase AS IPR020617 Thiolase C IPR020613 Thiolase CS IPR020616 Thiolase N IPR020615 Thiolase acyl enz int AS
rno:00500	Starch and sucrose metabolism	3.9	-1.2	3/0 proteins of 38 Pygb (-48.0): gpmDB | homo | protein -------------------- EXCEPTION -------------------- MSG: Could not connect to database rattus_norvegicus_core_57_34y as user ensro using [DBI:mysql:database=rattus_norvegicus_core_57_34y;host=ens-ca-db1a;port=5306] as a locator: Can't connect to MySQL server on 'ens-ca-db1a' (113) STACK Bio::EnsEMBL::DBSQL::DBConnection::connect /ensemblweb/www/www_57/ensembl/modules/Bio/EnsEMBL/DBSQL/DBConnection.pm:299 STACK Bio::EnsEMBL::DBSQL::DBConnection::db_handle /ensemblweb/www/www_57/ensembl/modules/Bio/EnsEMBL/DBSQL/DBConnection.pm:618 STACK Bio::EnsEMBL::DBSQL::DBConnection::prepare /ensemblweb/www/www_57/ensembl/modules/Bio/EnsEMBL/DBSQL/DBConnection.pm:647 STACK Bio::EnsEMBL::DBSQL::BaseAdaptor::prepare /ensemblweb/www/www_57/ensembl/modules/Bio/EnsEMBL/DBSQL/BaseAdaptor.pm:164 STACK Bio::EnsEMBL::DBSQL::BaseMetaContainer::list_value_by_key /ensemblweb/www/www_57/ensembl/modules/Bio/EnsEMBL/DBSQL/BaseMetaContainer.pm:112 STACK Bio::EnsEMBL::DBSQL::BaseMetaContainer::get_schema_version /ensemblweb/www/www_57/ensembl/modules/Bio/EnsEMBL/DBSQL/BaseMetaContainer.pm:68 STACK Bio::EnsEMBL::Registry::version_check /ensemblweb/www/www_57/ensembl/modules/Bio/EnsEMBL/Registry.pm:2299 STACK Bio::EnsEMBL::Registry::get_adaptor /ensemblweb/www/www_57/ensembl/modules/Bio/EnsEMBL/Registry.pm:980 STACK Bio::EnsEMBL::DBSQL::DBAdaptor::AUTOLOAD /ensemblweb/www/www_57/ensembl/modules/Bio/EnsEMBL/DBSQL/DBAdaptor.pm:892 STACK EnsEMBL::Web::Factory::Transcript::createObjects /ensemblweb/www/www_57/modules/EnsEMBL/Web/Factory/Transcript.pm:82 STACK EnsEMBL::Web::Proxy::AUTOLOAD /ensemblweb/www/www_57/modules/EnsEMBL/Web/Proxy.pm:157 STACK (eval) /ensemblweb/www/www_57/modules/EnsEMBL/Web/Model.pm:117 STACK EnsEMBL::Web::Model::create_objects /ensemblweb/www/www_57/modules/EnsEMBL/Web/Model.pm:116 STACK EnsEMBL::Web::Magic::handler /ensemblweb/www/www_57/modules/EnsEMBL/Web/Magic.pm:144 STACK EnsEMBL::Web::Magic::stuff /ensemblweb/www/www_57/modules/EnsEMBL/Web/Magic.pm:43 STACK ModPerl::ROOT::ModPerl::Registry::ensemblweb_www_www_57_perl_default_action::handler /ensemblweb/www/www_57/perl/default/action:2 STACK (eval) /localsw/ensembl_web/apache/lib/site_perl/5.8.8/x86_64-linux-thread-multi/ModPerl/RegistryCooker.pm:204 STACK ModPerl::RegistryCooker::run /localsw/ensembl_web/apache/lib/site_perl/5.8.8/x86_64-linux-thread-multi/ModPerl/RegistryCooker.pm:204 STACK ModPerl::RegistryCooker::default_handler /localsw/ensembl_web/apache/lib/site_perl/5.8.8/x86_64-linux-thread-multi/ModPerl/RegistryCooker.pm:170 STACK ModPerl::Registry::handler /localsw/ensembl_web/apache/lib/site_perl/5.8.8/x86_64-linux-thread-multi/ModPerl/Registry.pm:31 STACK (eval) -e:0 STACK toplevel -e:0 --------------------------------------------------- Gpi (-32.3): gpmDB | homo | protein Glucose-6-phosphate isomerase (GPI)(EC 5.3.1.9)(Phosphoglucose isomerase)(PGI)(Phosphohexose isomerase)(PHI)(Autocrine motility factor)(AMF)(Neuroleukin)(NLK) Source: UniProtKB/Swiss-Prot Q6P6V0 IPR001672 G6P Isomerase IPR018189 Phosphoglucose isomerase CS Pgm1 (-18.0): gpmDB | homo | protein Phosphoglucomutase-1 (PGM 1)(EC 5.4.2.2)(Glucose phosphomutase 1) Source: UniProtKB/Swiss-Prot P38652 IPR005843 A-D-PHexomutase C IPR016066 A-D-PHexomutase CS IPR005841 A-D-PHexomutase N IPR005844 A-D-PHexomutase a/b/a-I IPR016055 A-D-PHexomutase a/b/a-I/II/III IPR005845 A-D-PHexomutase a/b/a-II IPR005846 A-D-PHexomutase a/b/a-III
rno:00480	Glutathione metabolism	3.8	-1.2	3/0 proteins of 41 Gpx2 (-42.4): gpmDB | homo | protein Glutathione peroxidase 2 (GSHPx-2)(GPx-2)(EC 1.11.1.9)(Glutathione peroxidase-gastrointestinal)(GSHPx-GI)(GPx-GI) Source: UniProtKB/Swiss-Prot P83645 IPR000889 Glutathione peroxidase IPR012336 Thioredoxin-like fold Idh2 (-16.1): gpmDB | homo | protein Isocitrate dehydrogenase [NADP], mitochondrial Precursor (IDH)(EC 1.1.1.42)(Oxalosuccinate decarboxylase)(NADP(+)-specific ICDH)(IDP)(ICD-M) Source: UniProtKB/Swiss-Prot P56574 IPR019818 IsoCit/isopropylmalate DH CS IPR001804 Isocitrate/isopropylmalate DH IPR004790 Isocitrate DH NADP-dep euk Idh1 (-14.6): gpmDB | homo | protein Isocitrate dehydrogenase [NADP] cytoplasmic (IDH)(EC 1.1.1.42)(Cytosolic NADP-isocitrate dehydrogenase)(Oxalosuccinate decarboxylase)(NADP(+)-specific ICDH)(IDP) Source: UniProtKB/Swiss-Prot P41562 IPR019818 IsoCit/isopropylmalate DH CS IPR001804 Isocitrate/isopropylmalate DH IPR004790 Isocitrate DH NADP-dep euk
rno:04080	Neuroactive ligand-receptor interaction	5.1	-1.1	1/4 proteins of 257 Prss1 (-25.4): gpmDB | homo | protein Anionic trypsin-1 Precursor (EC 3.4.21.4)(Anionic trypsin I)(Pretrypsinogen I)(Serine protease 1) Source: UniProtKB/Swiss-Prot P00762 IPR009003 Pept Trypsin-like Ser/Cys IPR018114 Peptidase S1/S6 AS IPR001314 Peptidase S1A IPR001254 Peptidase S1 S6
rno:04722	Neurotrophin signaling pathway	4.3	-1.0	4/2 proteins of 137 ENSRNOP00000030885 (-82.3): gpmDB | homo | protein 14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1)(KCIP-1)(Mitochondrial import stimulation factor S1 subunit) Source: UniProtKB/Swiss-Prot P63102 IPR000308 14-3-3 Ywhae (-42.3): gpmDB | homo | protein 14-3-3 protein epsilon (14-3-3E)(Mitochondrial import stimulation factor L subunit)(MSF L) Source: UniProtKB/Swiss-Prot P62260 IPR000308 14-3-3 Ywhaq (-17.7): gpmDB | homo | protein 14-3-3 protein theta (14-3-3 protein tau) Source: UniProtKB/Swiss-Prot P68255 IPR000308 14-3-3 Arhgdia (-4.4): gpmDB | homo | protein Rho GDP-dissociation inhibitor 1 (Rho GDI 1)(Rho-GDI alpha) Source: UniProtKB/Swiss-Prot Q5XI73 IPR014756 Ig E-set IPR000406 Rho GDI
rno:04010	MAPK signaling pathway	4.8	-0.8	2/4 proteins of 256 RGD1559849 (-259.7): gpmDB | homo | protein no description available IPR018181 Heat shock 70 CS IPR001023 Hsp70 IPR013126 Hsp 70 Hspa2 (-86.0): gpmDB | homo | protein Heat shock-related 70 kDa protein 2 (Heat shock protein 70.2)(Testis-specific heat shock protein-related)(HST) Source: UniProtKB/Swiss-Prot P14659 IPR018181 Heat shock 70 CS IPR001023 Hsp70 IPR013126 Hsp 70
rno:04360	Axon guidance	4.2	-0.7	3/2 proteins of 130 Dpysl2 (-92.6): gpmDB | homo | protein Dihydropyrimidinase-related protein 2 (DRP-2)(Turned on after division 64 kDa protein)(TOAD-64)(Collapsin response mediator protein 2)(CRMP-2) Source: UniProtKB/Swiss-Prot P47942 IPR006680 Amidohydro 1 IPR013108 Amidohydro 3 IPR011778 D-hydantoinase ENSRNOP00000028041 (-15.9): gpmDB | homo | protein Cofilin-1 (Cofilin, non-muscle isoform) Source: UniProtKB/Swiss-Prot P45592 IPR017904 ADF/Cofilin/Destrin IPR002108 Actin-bd cofilin/tropomyosin Gnai2 (-15.3): gpmDB | homo | protein Guanine nucleotide-binding protein G(i) subunit alpha-2 (Adenylate cyclase-inhibiting G alpha protein) Source: UniProtKB/Swiss-Prot P04897 IPR006688 ARF IPR002975 Fungi GproteinA IPR001019 Gprotein alph bd IPR000469 Gprotein alpha12 IPR001408 Gprotein alpha I IPR000367 Gprotein alpha S IPR001806 Ras GTPase
rno:04110	Cell cycle	4.3	-0.7	3/2 proteins of 115 ENSRNOP00000030885 (-82.3): gpmDB | homo | protein 14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1)(KCIP-1)(Mitochondrial import stimulation factor S1 subunit) Source: UniProtKB/Swiss-Prot P63102 IPR000308 14-3-3 Ywhae (-42.3): gpmDB | homo | protein 14-3-3 protein epsilon (14-3-3E)(Mitochondrial import stimulation factor L subunit)(MSF L) Source: UniProtKB/Swiss-Prot P62260 IPR000308 14-3-3 Ywhaq (-17.7): gpmDB | homo | protein 14-3-3 protein theta (14-3-3 protein tau) Source: UniProtKB/Swiss-Prot P68255 IPR000308 14-3-3
rno:00910	Nitrogen metabolism	3.7	-0.7	2/0 proteins of 22 Glud1 (-20.4): gpmDB | homo | protein Glutamate dehydrogenase 1, mitochondrial Precursor (GDH 1)(EC 1.4.1.3)(Memory-related gene 2 protein)(MRG-2) Source: UniProtKB/Swiss-Prot P10860 IPR006095 Glu/Leu/Phe/Val DH IPR006096 Glu/Leu/Phe/Val DH C IPR006097 Glu/Leu/Phe/Val DH dimer IPR016040 NAD(P)-bd dom Car7 (-6.5): gpmDB | homo | protein carbonic anhydrase 7 Source: RefSeq_peptide NP_001099635 IPR001148 Euk COanhd
rno:04512	ECM-receptor interaction	3.7	-0.7	2/1 proteins of 71 Col3a1 (-8.8): gpmDB | homo | protein Collagen alpha-1(III) chain Precursor Source: UniProtKB/Swiss-Prot P13941 IPR008160 Collagen IPR000885 Fib collagen C IPR002181 Fibrinogen a/b/g C IPR000694 PRO rich IPR006552 VWC out IPR001007 VWF C Col5a1 (-4.3): gpmDB | homo | protein Collagen alpha-1(V) chain Precursor Source: UniProtKB/Swiss-Prot Q9JI03 IPR008160 Collagen IPR008985 ConA-like lec gl IPR000885 Fib collagen C IPR002181 Fibrinogen a/b/g C IPR001791 Laminin G IPR012680 Laminin G 2 IPR003129 Laminin G thrombospondin N IPR000694 PRO rich
rno:00052	Galactose metabolism	3.6	-0.7	2/0 proteins of 21 Pgm1 (-18.0): gpmDB | homo | protein Phosphoglucomutase-1 (PGM 1)(EC 5.4.2.2)(Glucose phosphomutase 1) Source: UniProtKB/Swiss-Prot P38652 IPR005843 A-D-PHexomutase C IPR016066 A-D-PHexomutase CS IPR005841 A-D-PHexomutase N IPR005844 A-D-PHexomutase a/b/a-I IPR016055 A-D-PHexomutase a/b/a-I/II/III IPR005845 A-D-PHexomutase a/b/a-II IPR005846 A-D-PHexomutase a/b/a-III Akr1b1-ps2 (-6.2): gpmDB | homo | protein Aldose reductase (AR)(EC 1.1.1.21)(Aldehyde reductase) Source: UniProtKB/Swiss-Prot P07943 IPR001395 Aldo/ket red IPR018170 Aldo/ket reductase CS IPR020471 Aldo/keto reductase sg
rno:04142	Lysosome	4.5	-0.7	2/1 proteins of 96 Cltc (-286.8): gpmDB | homo | protein Clathrin heavy chain 1 Source: UniProtKB/Swiss-Prot P11442 IPR016024 ARM-type fold IPR000547 Clathrin H-chain/VPS repeat IPR015348 Clathrin H-chain linker core IPR001473 Clathrin H-chain propeller N IPR016341 Clathrin heavy chain ENSRNOP00000011045 (-16.6): gpmDB | homo | protein Alpha-N-acetylgalactosaminidase Precursor (EC 3.2.1.49)(Alpha-galactosidase B) [Source: UniProt Q66H12] Source: 3.2.1.49 IPR002241 Glyco hydro 27 IPR000111 Glyco hydro GHD IPR017853 Glyco hydro catalytic core
rno:00260	Glycine, serine and threonine metabolism	3.7	-0.7	2/0 proteins of 26 Psat1 (-46.3): gpmDB | homo | protein phosphoserine aminotransferase 1 [Source:RefSeq peptide;Acc:NP_942033] IPR000192 Aminotrans V/Cys dSase IPR020578 Aminotrans V PyrdxlP BS IPR003248 Pser amintransf IPR015424 PyrdxlP-dep Trfase major ENSRNOP00000026185 (-5.1): gpmDB | homo | protein D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH). [Source: UniProt O08651] Source: 1.1.1.95 IPR006139 2 Hacid DH IPR006140 2hydac DH NAD bd IPR006236 PGDH
rno:04666	Fc gamma R-mediated phagocytosis	4.3	-0.7	2/1 proteins of 95 ENSRNOP00000025857 (-124.1): gpmDB | homo | protein Gelsolin Precursor (Actin-depolymerizing factor)(ADF)(Brevin) [Source: UniProt Q68FP1] IPR007122 Gelsolin IPR007123 Gelsoln ENSRNOP00000028041 (-15.9): gpmDB | homo | protein Cofilin-1 (Cofilin, non-muscle isoform) Source: UniProtKB/Swiss-Prot P45592 IPR017904 ADF/Cofilin/Destrin IPR002108 Actin-bd cofilin/tropomyosin
rno:00072	Synthesis and degradation of ketone bodies	3.7	-0.7	2/0 proteins of 7 ENSRNOP00000020798 (-28.6): gpmDB | homo | protein Succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial Precursor (EC 2.8.3.5)(3-oxoacid-CoA transferase 1)(Somatic-type succinyl CoA:3-oxoacid CoA-transferase)(Scot-S) [Source: UniProt B2GV06] Source: 2.8.3.5 IPR012792 3-oxoacid CoA-transf A IPR014388 3-oxoacid CoA-transferase IPR004165 CoA trans IPR004164 CoA transf AS IPR004163 CoA transf BS Acat1 (-12.6): gpmDB | homo | protein Acetyl-CoA acetyltransferase, mitochondrial Precursor (EC 2.3.1.9)(Acetoacetyl-CoA thiolase) Source: UniProtKB/Swiss-Prot P17764 IPR002155 Thiolase IPR016039 Thiolase-like IPR020610 Thiolase AS IPR020617 Thiolase C IPR020613 Thiolase CS IPR020616 Thiolase N IPR020615 Thiolase acyl enz int AS
rno:00510	N-Glycan biosynthesis	4.1	-0.7	2/0 proteins of 41 ENSRNOP00000026794 (-71.7): gpmDB | homo | protein neutral alpha-glucosidase AB [Source:RefSeq peptide;Acc:NP_001099804] IPR000322 Glyco hydro 31 IPR017853 Glyco hydro catalytic core ENSRNOP00000010209 (-24.2): gpmDB | homo | protein Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 Precursor (EC 2.4.1.119)(Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit)(Ribophorin-2)(Ribophorin II)(RPN-II) Source: UniProtKB/Swiss-Prot P25235
rno:00250	Alanine, aspartate and glutamate metabolism	4.2	-0.7	2/0 proteins of 29 LOC314123 (-110.0): gpmDB | homo | protein Aspartate aminotransferase, mitochondrial Precursor (mAspAT)(EC 2.6.1.1)(Transaminase A)(Glutamate oxaloacetate transaminase 2)(Fatty acid-binding protein)(FABP-1)(Plasma membrane-associated fatty acid-binding protein)(FABPpm) Source: UniProtKB/Swiss-Prot P00507 IPR004839 Aminotrans I/II IPR000796 Asp trans IPR008120 Dense granule Gra7 protein IPR004838 NHTrfase class1 PyrdxlP-BS IPR015424 PyrdxlP-dep Trfase major Glud1 (-20.4): gpmDB | homo | protein Glutamate dehydrogenase 1, mitochondrial Precursor (GDH 1)(EC 1.4.1.3)(Memory-related gene 2 protein)(MRG-2) Source: UniProtKB/Swiss-Prot P10860 IPR006095 Glu/Leu/Phe/Val DH IPR006096 Glu/Leu/Phe/Val DH C IPR006097 Glu/Leu/Phe/Val DH dimer IPR016040 NAD(P)-bd dom
rno:04916	Melanogenesis	3.3	-0.7	2/1 proteins of 97 Gnai2 (-15.3): gpmDB | homo | protein Guanine nucleotide-binding protein G(i) subunit alpha-2 (Adenylate cyclase-inhibiting G alpha protein) Source: UniProtKB/Swiss-Prot P04897 IPR006688 ARF IPR002975 Fungi GproteinA IPR001019 Gprotein alph bd IPR000469 Gprotein alpha12 IPR001408 Gprotein alpha I IPR000367 Gprotein alpha S IPR001806 Ras GTPase Gnao1 (-7.7): gpmDB | homo | protein Guanine nucleotide-binding protein G(o) subunit alpha Source: UniProtKB/Swiss-Prot P59215 IPR006688 ARF IPR002975 Fungi GproteinA IPR001019 Gprotein alph bd IPR001408 Gprotein alpha I IPR001806 Ras GTPase
rno:00561	Glycerolipid metabolism	3.8	-0.7	2/0 proteins of 38 Aldh9a1 (-28.6): gpmDB | homo | protein 4-trimethylaminobutyraldehyde dehydrogenase (TMABADH)(EC 1.2.1.47)(Aldehyde dehydrogenase family 9 member A1)(EC 1.2.1.3) Source: UniProtKB/Swiss-Prot Q9JLJ3 Akr1b1-ps2 (-6.2): gpmDB | homo | protein Aldose reductase (AR)(EC 1.1.1.21)(Aldehyde reductase) Source: UniProtKB/Swiss-Prot P07943 IPR001395 Aldo/ket red IPR018170 Aldo/ket reductase CS IPR020471 Aldo/keto reductase sg
rno:00071	Fatty acid metabolism	3.8	-0.7	2/0 proteins of 41 Aldh9a1 (-28.6): gpmDB | homo | protein 4-trimethylaminobutyraldehyde dehydrogenase (TMABADH)(EC 1.2.1.47)(Aldehyde dehydrogenase family 9 member A1)(EC 1.2.1.3) Source: UniProtKB/Swiss-Prot Q9JLJ3 Acat1 (-12.6): gpmDB | homo | protein Acetyl-CoA acetyltransferase, mitochondrial Precursor (EC 2.3.1.9)(Acetoacetyl-CoA thiolase) Source: UniProtKB/Swiss-Prot P17764 IPR002155 Thiolase IPR016039 Thiolase-like IPR020610 Thiolase AS IPR020617 Thiolase C IPR020613 Thiolase CS IPR020616 Thiolase N IPR020615 Thiolase acyl enz int AS
rno:04144	Endocytosis	5.0	-0.6	3/3 proteins of 202 Cltc (-286.8): gpmDB | homo | protein Clathrin heavy chain 1 Source: UniProtKB/Swiss-Prot P11442 IPR016024 ARM-type fold IPR000547 Clathrin H-chain/VPS repeat IPR015348 Clathrin H-chain linker core IPR001473 Clathrin H-chain propeller N IPR016341 Clathrin heavy chain RGD1559849 (-259.7): gpmDB | homo | protein no description available IPR018181 Heat shock 70 CS IPR001023 Hsp70 IPR013126 Hsp 70 Hspa2 (-86.0): gpmDB | homo | protein Heat shock-related 70 kDa protein 2 (Heat shock protein 70.2)(Testis-specific heat shock protein-related)(HST) Source: UniProtKB/Swiss-Prot P14659 IPR018181 Heat shock 70 CS IPR001023 Hsp70 IPR013126 Hsp 70
rno:04062	Chemokine signaling pathway	3.9	-0.6	2/3 proteins of 176 Gnb1 (-37.3): gpmDB | homo | protein Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1) Source: UniProtKB/Swiss-Prot P54311 IPR020472 G-protein beta WD-40 rep reg IPR001632 Gprotein B IPR016346 Guanine nucleotide-bd bsu IPR001680 WD40 repeat IPR011046 WD40 repeat-like IPR019782 WD40 repeat 2 IPR019775 WD40 repeat CS IPR017986 WD40 repeat dom IPR019781 WD40 repeat sg Gnai2 (-15.3): gpmDB | homo | protein Guanine nucleotide-binding protein G(i) subunit alpha-2 (Adenylate cyclase-inhibiting G alpha protein) Source: UniProtKB/Swiss-Prot P04897 IPR006688 ARF IPR002975 Fungi GproteinA IPR001019 Gprotein alph bd IPR000469 Gprotein alpha12 IPR001408 Gprotein alpha I IPR000367 Gprotein alpha S IPR001806 Ras GTPase
rno:04910	Insulin signaling pathway	3.4	-0.6	1/2 proteins of 137 Pygb (-48.0): gpmDB | homo | protein -------------------- EXCEPTION -------------------- MSG: Could not connect to database rattus_norvegicus_core_57_34y as user ensro using [DBI:mysql:database=rattus_norvegicus_core_57_34y;host=ens-ca-db1a;port=5306] as a locator: Can't connect to MySQL server on 'ens-ca-db1a' (113) STACK Bio::EnsEMBL::DBSQL::DBConnection::connect /ensemblweb/www/www_57/ensembl/modules/Bio/EnsEMBL/DBSQL/DBConnection.pm:299 STACK Bio::EnsEMBL::DBSQL::DBConnection::db_handle /ensemblweb/www/www_57/ensembl/modules/Bio/EnsEMBL/DBSQL/DBConnection.pm:618 STACK Bio::EnsEMBL::DBSQL::DBConnection::prepare /ensemblweb/www/www_57/ensembl/modules/Bio/EnsEMBL/DBSQL/DBConnection.pm:647 STACK Bio::EnsEMBL::DBSQL::BaseAdaptor::prepare /ensemblweb/www/www_57/ensembl/modules/Bio/EnsEMBL/DBSQL/BaseAdaptor.pm:164 STACK Bio::EnsEMBL::DBSQL::BaseMetaContainer::list_value_by_key /ensemblweb/www/www_57/ensembl/modules/Bio/EnsEMBL/DBSQL/BaseMetaContainer.pm:112 STACK Bio::EnsEMBL::DBSQL::BaseMetaContainer::get_schema_version /ensemblweb/www/www_57/ensembl/modules/Bio/EnsEMBL/DBSQL/BaseMetaContainer.pm:68 STACK Bio::EnsEMBL::Registry::version_check /ensemblweb/www/www_57/ensembl/modules/Bio/EnsEMBL/Registry.pm:2299 STACK Bio::EnsEMBL::Registry::get_adaptor /ensemblweb/www/www_57/ensembl/modules/Bio/EnsEMBL/Registry.pm:980 STACK Bio::EnsEMBL::DBSQL::DBAdaptor::AUTOLOAD /ensemblweb/www/www_57/ensembl/modules/Bio/EnsEMBL/DBSQL/DBAdaptor.pm:892 STACK EnsEMBL::Web::Factory::Transcript::createObjects /ensemblweb/www/www_57/modules/EnsEMBL/Web/Factory/Transcript.pm:82 STACK EnsEMBL::Web::Proxy::AUTOLOAD /ensemblweb/www/www_57/modules/EnsEMBL/Web/Proxy.pm:157 STACK (eval) /ensemblweb/www/www_57/modules/EnsEMBL/Web/Model.pm:117 STACK EnsEMBL::Web::Model::create_objects /ensemblweb/www/www_57/modules/EnsEMBL/Web/Model.pm:116 STACK EnsEMBL::Web::Magic::handler /ensemblweb/www/www_57/modules/EnsEMBL/Web/Magic.pm:144 STACK EnsEMBL::Web::Magic::stuff /ensemblweb/www/www_57/modules/EnsEMBL/Web/Magic.pm:43 STACK ModPerl::ROOT::ModPerl::Registry::ensemblweb_www_www_57_perl_default_action::handler /ensemblweb/www/www_57/perl/default/action:2 STACK (eval) /localsw/ensembl_web/apache/lib/site_perl/5.8.8/x86_64-linux-thread-multi/ModPerl/RegistryCooker.pm:204 STACK ModPerl::RegistryCooker::run /localsw/ensembl_web/apache/lib/site_perl/5.8.8/x86_64-linux-thread-multi/ModPerl/RegistryCooker.pm:204 STACK ModPerl::RegistryCooker::default_handler /localsw/ensembl_web/apache/lib/site_perl/5.8.8/x86_64-linux-thread-multi/ModPerl/RegistryCooker.pm:170 STACK ModPerl::Registry::handler /localsw/ensembl_web/apache/lib/site_perl/5.8.8/x86_64-linux-thread-multi/ModPerl/Registry.pm:31 STACK (eval) -e:0 STACK toplevel -e:0 ---------------------------------------------------
rno:04514	Cell adhesion molecules (CAMs)	2.9	-0.6	1/2 proteins of 145 Mpz (-14.3): gpmDB | homo | protein Myelin protein P0 Precursor (Myelin protein zero)(Myelin peripheral protein)(MPP) Source: UniProtKB/Swiss-Prot P06907 IPR007110 Ig-like IPR013106 Ig V-set IPR003596 Ig V-set sub IPR003599 Ig sub IPR003598 Ig sub2 IPR000920 Myelin P0 IPR019738 Myelin P0 CS
rno:03010	Ribosome	3.1	-0.6	1/2 proteins of 121 Rpsa (-6.2): gpmDB | homo | protein 40S ribosomal protein SA (Laminin receptor 1)(LamR)(37/67 kDa laminin receptor)(LRP/LR)(Laminin-binding protein precursor p40)(LBP/p40)(37 kDa laminin receptor precursor)(37LRP)(67 kDa laminin receptor)(67LR) Source: UniProtKB/Swiss-Prot P38983 IPR001865 Ribosomal S2 IPR018130 Ribosomal S2 CS IPR005707 Ribosomal S2 euk/arc
rno:00230	Purine metabolism	4.3	-0.6	2/2 proteins of 154 ENSRNOP00000049742 (-150.3): gpmDB | homo | protein KPYM_RAT Isoform M2 of P11980 - Rattus norvegicus (Rat) [Source:UniProtKB/SpliceVariant;Acc:P11980-2] IPR001697 Pyr Knase IPR015795 Pyrv Knase C-like IPR015794 Pyrv Knase a/b IPR015793 Pyrv Knase brl RGD1559750 (-29.4): gpmDB | homo | protein Bifunctional purine biosynthesis protein PURH [Includes Phosphoribosylaminoimidazolecarboxamide formyltransferase(EC 2.1.2.3)(5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase)(AICAR transformylase);IMP cyclohydrolase(EC 3.5.4.10)(Inos /.../e)(IMP synthetase)(ATIC)] Source: UniProtKB/Swiss-Prot O35567 IPR002695 AICARFT IMPCHas IPR013982 AICARFT IMPCHas formly IPR011607 MGS
rno:04310	Wnt signaling pathway	3.3	-0.6	2/2 proteins of 139 ENSRNOP00000014609 (-7.6): gpmDB | homo | protein Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A subunit A isoform PR65-beta)(PP2A subunit A isoform R1-beta) Source: UniProtKB/Swiss-Prot Q4QQT4 IPR016024 ARM-type fold IPR000357 HEAT IPR021133 HEAT type 2 IPR001160 Peptidase M20C Ruvbl1 (-5.6): gpmDB | homo | protein RuvB-like 1 (EC 3.6.1.-)(49 kDa TATA box-binding protein-interacting protein)(49 kDa TBP-interacting protein)(TIP49a)(Pontin 52)(DNA helicase p50) Source: UniProtKB/Swiss-Prot P60123 IPR003593 ATPase AAA+ core IPR003959 ATPase AAA core IPR010339 TIP49 C
rno:04120	Ubiquitin mediated proteolysis	4.3	-0.6	2/2 proteins of 124 Fbxo2 (-99.5): gpmDB | homo | protein F-box protein 2 [Source:RefSeq peptide;Acc:NP_445963] IPR001810 F-box IPR007397 FBA region IPR008979 Galactose-bd-like Uba1 (-61.2): gpmDB | homo | protein Ubiquitin-like modifier-activating enzyme 1 (Ubiquitin-activating enzyme E1) Source: UniProtKB/Swiss-Prot Q5U300 IPR009036 Molybdenum cofac synth MoeB IPR000594 ThiF NAD FAD bd IPR018075 UBQ-activ enz E1 IPR000011 UBQ-activ enz E1-like IPR018074 UBQ-activ enz E1 AS IPR000127 UBact repeat
rno:04930	Type II diabetes mellitus	4.2	-0.4	1/1 proteins of 54 ENSRNOP00000049742 (-150.3): gpmDB | homo | protein KPYM_RAT Isoform M2 of P11980 - Rattus norvegicus (Rat) [Source:UniProtKB/SpliceVariant;Acc:P11980-2] IPR001697 Pyr Knase IPR015795 Pyrv Knase C-like IPR015794 Pyrv Knase a/b IPR015793 Pyrv Knase brl
rno:00562	Inositol phosphate metabolism	3.2	-0.4	1/1 proteins of 58 ENSRNOP00000039702 (-25.2): gpmDB | homo | protein triosephosphate isomerase Source: RefSeq_peptide NP_001028244 IPR000652 Triophos ismrse
rno:00590	Arachidonic acid metabolism	3.5	-0.4	1/1 proteins of 60 Gpx2 (-42.4): gpmDB | homo | protein Glutathione peroxidase 2 (GSHPx-2)(GPx-2)(EC 1.11.1.9)(Glutathione peroxidase-gastrointestinal)(GSHPx-GI)(GPx-GI) Source: UniProtKB/Swiss-Prot P83645 IPR000889 Glutathione peroxidase IPR012336 Thioredoxin-like fold
rno:04640	Hematopoietic cell lineage	3.5	-0.4	1/1 proteins of 78 Mme (-30.2): gpmDB | homo | protein Neprilysin (EC 3.4.24.11)(Neutral endopeptidase 24.11)(Neutral endopeptidase)(NEP)(Enkephalinase)(Atriopeptidase)(CD10 antigen) Source: UniProtKB/Swiss-Prot P07861 IPR018497 Peptidase M13 C IPR008753 Peptidase M13 N
rno:00603	Glycosphingolipid biosynthesis - globo series	3.2	-0.4	1/0 proteins of 12 ENSRNOP00000011045 (-16.6): gpmDB | homo | protein Alpha-N-acetylgalactosaminidase Precursor (EC 3.2.1.49)(Alpha-galactosidase B) [Source: UniProt Q66H12] Source: 3.2.1.49 IPR002241 Glyco hydro 27 IPR000111 Glyco hydro GHD IPR017853 Glyco hydro catalytic core
rno:00950	Isoquinoline alkaloid biosynthesis	4.1	-0.4	1/0 proteins of 7 LOC314123 (-110.0): gpmDB | homo | protein Aspartate aminotransferase, mitochondrial Precursor (mAspAT)(EC 2.6.1.1)(Transaminase A)(Glutamate oxaloacetate transaminase 2)(Fatty acid-binding protein)(FABP-1)(Plasma membrane-associated fatty acid-binding protein)(FABPpm) Source: UniProtKB/Swiss-Prot P00507 IPR004839 Aminotrans I/II IPR000796 Asp trans IPR008120 Dense granule Gra7 protein IPR004838 NHTrfase class1 PyrdxlP-BS IPR015424 PyrdxlP-dep Trfase major
rno:00401	Novobiocin biosynthesis	4.1	-0.4	1/0 proteins of 3 LOC314123 (-110.0): gpmDB | homo | protein Aspartate aminotransferase, mitochondrial Precursor (mAspAT)(EC 2.6.1.1)(Transaminase A)(Glutamate oxaloacetate transaminase 2)(Fatty acid-binding protein)(FABP-1)(Plasma membrane-associated fatty acid-binding protein)(FABPpm) Source: UniProtKB/Swiss-Prot P00507 IPR004839 Aminotrans I/II IPR000796 Asp trans IPR008120 Dense granule Gra7 protein IPR004838 NHTrfase class1 PyrdxlP-BS IPR015424 PyrdxlP-dep Trfase major
rno:00350	Tyrosine metabolism	4.1	-0.4	1/0 proteins of 29 LOC314123 (-110.0): gpmDB | homo | protein Aspartate aminotransferase, mitochondrial Precursor (mAspAT)(EC 2.6.1.1)(Transaminase A)(Glutamate oxaloacetate transaminase 2)(Fatty acid-binding protein)(FABP-1)(Plasma membrane-associated fatty acid-binding protein)(FABPpm) Source: UniProtKB/Swiss-Prot P00507 IPR004839 Aminotrans I/II IPR000796 Asp trans IPR008120 Dense granule Gra7 protein IPR004838 NHTrfase class1 PyrdxlP-BS IPR015424 PyrdxlP-dep Trfase major
rno:00983	Drug metabolism - other enzymes	3.4	-0.4	1/0 proteins of 45 LOC291863 (-13.4): gpmDB | homo | protein Carboxylesterase 3 Precursor (EC 3.1.1.1)(EC 3.1.1.67)(Liver carboxylesterase 10)(Carboxyesterase ES-10)(Fatty acid ethyl ester synthase)(FAEE synthase)(pI 6.1 esterase)(ES-HVEL) Source: UniProtKB/Swiss-Prot P16303 IPR002018 CarbesteraseB IPR019826 Carboxylesterase B AS IPR019819 Carboxylesterase B CS IPR000997 Cholinesterase
rno:00400	Phenylalanine, tyrosine and tryptophan biosynthesis	4.1	-0.4	1/0 proteins of 5 LOC314123 (-110.0): gpmDB | homo | protein Aspartate aminotransferase, mitochondrial Precursor (mAspAT)(EC 2.6.1.1)(Transaminase A)(Glutamate oxaloacetate transaminase 2)(Fatty acid-binding protein)(FABP-1)(Plasma membrane-associated fatty acid-binding protein)(FABPpm) Source: UniProtKB/Swiss-Prot P00507 IPR004839 Aminotrans I/II IPR000796 Asp trans IPR008120 Dense granule Gra7 protein IPR004838 NHTrfase class1 PyrdxlP-BS IPR015424 PyrdxlP-dep Trfase major
rno:00340	Histidine metabolism	3.7	-0.4	1/0 proteins of 23 Aldh9a1 (-28.6): gpmDB | homo | protein 4-trimethylaminobutyraldehyde dehydrogenase (TMABADH)(EC 1.2.1.47)(Aldehyde dehydrogenase family 9 member A1)(EC 1.2.1.3) Source: UniProtKB/Swiss-Prot Q9JLJ3
rno:00632	Benzoate degradation via CoA ligation	3.1	-0.4	1/0 proteins of 9 Acat1 (-12.6): gpmDB | homo | protein Acetyl-CoA acetyltransferase, mitochondrial Precursor (EC 2.3.1.9)(Acetoacetyl-CoA thiolase) Source: UniProtKB/Swiss-Prot P17764 IPR002155 Thiolase IPR016039 Thiolase-like IPR020610 Thiolase AS IPR020617 Thiolase C IPR020613 Thiolase CS IPR020616 Thiolase N IPR020615 Thiolase acyl enz int AS
rno:00240	Pyrimidine metabolism	3.2	-0.4	1/1 proteins of 94 Txnrd1 (-6.2): gpmDB | homo | protein Thioredoxin reductase 1, cytoplasmic (TR)(EC 1.8.1.9)(Thioredoxin reductase TR1)(NADPH-dependent thioredoxin reductase) Source: UniProtKB/Swiss-Prot O89049 IPR016156 FAD/NAD-linked Rdtase dimer IPR013027 FAD pyr nucl-diS OxRdtase IPR000815 Hg reductase IPR012999 Pyr OxRdtase I AS IPR001327 Pyr OxRdtase NAD bd IPR004099 Pyr nucl-diS OxRdtase dimer IPR000103 Pyridine nuc-diS OxRdtase 2 IPR006338 Reduct Se
rno:00900	Terpenoid backbone biosynthesis	3.1	-0.4	1/0 proteins of 11 Acat1 (-12.6): gpmDB | homo | protein Acetyl-CoA acetyltransferase, mitochondrial Precursor (EC 2.3.1.9)(Acetoacetyl-CoA thiolase) Source: UniProtKB/Swiss-Prot P17764 IPR002155 Thiolase IPR016039 Thiolase-like IPR020610 Thiolase AS IPR020617 Thiolase C IPR020613 Thiolase CS IPR020616 Thiolase N IPR020615 Thiolase acyl enz int AS
rno:00520	Amino sugar and nucleotide sugar metabolism	3.3	-0.4	1/0 proteins of 41 Pgm1 (-18.0): gpmDB | homo | protein Phosphoglucomutase-1 (PGM 1)(EC 5.4.2.2)(Glucose phosphomutase 1) Source: UniProtKB/Swiss-Prot P38652 IPR005843 A-D-PHexomutase C IPR016066 A-D-PHexomutase CS IPR005841 A-D-PHexomutase N IPR005844 A-D-PHexomutase a/b/a-I IPR016055 A-D-PHexomutase a/b/a-I/II/III IPR005845 A-D-PHexomutase a/b/a-II IPR005846 A-D-PHexomutase a/b/a-III
rno:04940	Type I diabetes mellitus	4.2	-0.4	1/1 proteins of 66 RGD1563524 (-120.7): gpmDB | homo | protein 60 kDa heat shock protein, mitochondrial Precursor (Heat shock protein 60)(HSP-60)(Hsp60)(60 kDa chaperonin)(Chaperonin 60)(CPN60)(Mitochondrial matrix protein P1)(HSP-65) Source: UniProtKB/Swiss-Prot P63039 IPR017998 Chaperone TCP-1 IPR018370 Chaperonin Cpn60 CS IPR001844 Chaprnin Cpn60 IPR002423 Cpn60/TCP-1
rno:00960	Tropane, piperidine and pyridine alkaloid biosynthesis	3.4	-0.4	1/0 proteins of 7 LOC291863 (-13.4): gpmDB | homo | protein Carboxylesterase 3 Precursor (EC 3.1.1.1)(EC 3.1.1.67)(Liver carboxylesterase 10)(Carboxyesterase ES-10)(Fatty acid ethyl ester synthase)(FAEE synthase)(pI 6.1 esterase)(ES-HVEL) Source: UniProtKB/Swiss-Prot P16303 IPR002018 CarbesteraseB IPR019826 Carboxylesterase B AS IPR019819 Carboxylesterase B CS IPR000997 Cholinesterase
rno:00750	Vitamin B6 metabolism	3.6	-0.4	1/0 proteins of 3 Psat1 (-46.3): gpmDB | homo | protein phosphoserine aminotransferase 1 [Source:RefSeq peptide;Acc:NP_942033] IPR000192 Aminotrans V/Cys dSase IPR020578 Aminotrans V PyrdxlP BS IPR003248 Pser amintransf IPR015424 PyrdxlP-dep Trfase major
rno:04350	TGF-beta signaling pathway	3.0	-0.4	1/1 proteins of 80 ENSRNOP00000014609 (-7.6): gpmDB | homo | protein Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A subunit A isoform PR65-beta)(PP2A subunit A isoform R1-beta) Source: UniProtKB/Swiss-Prot Q4QQT4 IPR016024 ARM-type fold IPR000357 HEAT IPR021133 HEAT type 2 IPR001160 Peptidase M20C
rno:04610	Complement and coagulation cascades	3.1	-0.4	1/1 proteins of 61 Fgg (-13.6): gpmDB | homo | protein Fibrinogen gamma chain Precursor Source: UniProtKB/Swiss-Prot P02680 IPR020837 Fibrinogen CS IPR002181 Fibrinogen a/b/g C
rno:00040	Pentose and glucuronate interconversions	3.3	-0.4	1/0 proteins of 21 Akr1b1-ps2 (-6.2): gpmDB | homo | protein Aldose reductase (AR)(EC 1.1.1.21)(Aldehyde reductase) Source: UniProtKB/Swiss-Prot P07943 IPR001395 Aldo/ket red IPR018170 Aldo/ket reductase CS IPR020471 Aldo/keto reductase sg
rno:00410	beta-Alanine metabolism	3.7	-0.4	1/0 proteins of 19 Aldh9a1 (-28.6): gpmDB | homo | protein 4-trimethylaminobutyraldehyde dehydrogenase (TMABADH)(EC 1.2.1.47)(Aldehyde dehydrogenase family 9 member A1)(EC 1.2.1.3) Source: UniProtKB/Swiss-Prot Q9JLJ3
rno:00360	Phenylalanine metabolism	4.1	-0.4	1/0 proteins of 14 LOC314123 (-110.0): gpmDB | homo | protein Aspartate aminotransferase, mitochondrial Precursor (mAspAT)(EC 2.6.1.1)(Transaminase A)(Glutamate oxaloacetate transaminase 2)(Fatty acid-binding protein)(FABP-1)(Plasma membrane-associated fatty acid-binding protein)(FABPpm) Source: UniProtKB/Swiss-Prot P00507 IPR004839 Aminotrans I/II IPR000796 Asp trans IPR008120 Dense granule Gra7 protein IPR004838 NHTrfase class1 PyrdxlP-BS IPR015424 PyrdxlP-dep Trfase major
rno:00680	Methane metabolism	3.5	-0.4	1/0 proteins of 5 Cat (-35.7): gpmDB | homo | protein Catalase (EC 1.11.1.6) Source: UniProtKB/Swiss-Prot P04762 IPR002226 Catalase IPR020835 Catalase-like haem-dep IPR018028 Catalase rel subgroup
rno:00471	D-Glutamine and D-glutamate metabolism	3.6	-0.4	1/0 proteins of 3 Glud1 (-20.4): gpmDB | homo | protein Glutamate dehydrogenase 1, mitochondrial Precursor (GDH 1)(EC 1.4.1.3)(Memory-related gene 2 protein)(MRG-2) Source: UniProtKB/Swiss-Prot P10860 IPR006095 Glu/Leu/Phe/Val DH IPR006096 Glu/Leu/Phe/Val DH C IPR006097 Glu/Leu/Phe/Val DH dimer IPR016040 NAD(P)-bd dom
rno:00903	Limonene and pinene degradation	3.7	-0.4	1/0 proteins of 10 Aldh9a1 (-28.6): gpmDB | homo | protein 4-trimethylaminobutyraldehyde dehydrogenase (TMABADH)(EC 1.2.1.47)(Aldehyde dehydrogenase family 9 member A1)(EC 1.2.1.3) Source: UniProtKB/Swiss-Prot Q9JLJ3
rno:00450	Selenoamino acid metabolism	3.4	-0.4	1/0 proteins of 17 LOC500370 (-18.5): gpmDB | homo | protein Adenosylhomocysteinase (AdoHcyase)(EC 3.3.1.1)(S-adenosyl-L-homocysteine hydrolase) Source: UniProtKB/Swiss-Prot P10760 IPR015878 Ado hCys hydrolase NAD-bd IPR000043 S-Ado-L-homoCys hydrolase IPR020082 S-Ado-L-homoCys hydrolase CS
rno:04614	Renin-angiotensin system	3.5	-0.4	1/0 proteins of 16 Mme (-30.2): gpmDB | homo | protein Neprilysin (EC 3.4.24.11)(Neutral endopeptidase 24.11)(Neutral endopeptidase)(NEP)(Enkephalinase)(Atriopeptidase)(CD10 antigen) Source: UniProtKB/Swiss-Prot P07861 IPR018497 Peptidase M13 C IPR008753 Peptidase M13 N
rno:04742	Taste transduction	3.5	-0.4	1/0 proteins of 42 Gnb1 (-37.3): gpmDB | homo | protein Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1) Source: UniProtKB/Swiss-Prot P54311 IPR020472 G-protein beta WD-40 rep reg IPR001632 Gprotein B IPR016346 Guanine nucleotide-bd bsu IPR001680 WD40 repeat IPR011046 WD40 repeat-like IPR019782 WD40 repeat 2 IPR019775 WD40 repeat CS IPR017986 WD40 repeat dom IPR019781 WD40 repeat sg
rno:00053	Ascorbate and aldarate metabolism	3.7	-0.4	1/0 proteins of 23 Aldh9a1 (-28.6): gpmDB | homo | protein 4-trimethylaminobutyraldehyde dehydrogenase (TMABADH)(EC 1.2.1.47)(Aldehyde dehydrogenase family 9 member A1)(EC 1.2.1.3) Source: UniProtKB/Swiss-Prot Q9JLJ3
rno:00641	3-Chloroacrylic acid degradation	3.7	-0.4	1/0 proteins of 8 Aldh9a1 (-28.6): gpmDB | homo | protein 4-trimethylaminobutyraldehyde dehydrogenase (TMABADH)(EC 1.2.1.47)(Aldehyde dehydrogenase family 9 member A1)(EC 1.2.1.3) Source: UniProtKB/Swiss-Prot Q9JLJ3
rno:00521	Streptomycin biosynthesis	3.3	-0.4	1/0 proteins of 7 Pgm1 (-18.0): gpmDB | homo | protein Phosphoglucomutase-1 (PGM 1)(EC 5.4.2.2)(Glucose phosphomutase 1) Source: UniProtKB/Swiss-Prot P38652 IPR005843 A-D-PHexomutase C IPR016066 A-D-PHexomutase CS IPR005841 A-D-PHexomutase N IPR005844 A-D-PHexomutase a/b/a-I IPR016055 A-D-PHexomutase a/b/a-I/II/III IPR005845 A-D-PHexomutase a/b/a-II IPR005846 A-D-PHexomutase a/b/a-III
rno:00670	One carbon pool by folate	3.6	-0.4	1/0 proteins of 14 RGD1559750 (-29.4): gpmDB | homo | protein Bifunctional purine biosynthesis protein PURH [Includes Phosphoribosylaminoimidazolecarboxamide formyltransferase(EC 2.1.2.3)(5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase)(AICAR transformylase);IMP cyclohydrolase(EC 3.5.4.10)(Inos /.../e)(IMP synthetase)(ATIC)] Source: UniProtKB/Swiss-Prot O35567 IPR002695 AICARFT IMPCHas IPR013982 AICARFT IMPCHas formly IPR011607 MGS
KEGG:0	other	6.3	-	146 proteins ENSRNOP00000014996 (-490.5): gpmDB | homo | protein otogelin [Source:RefSeq peptide;Acc:NP_001099732] IPR007934 AbfB IPR014853 Conserved-cysteine-rich domain IPR006207 Cys knot C IPR000742 EGF 3 IPR002919 Prot Inh CR TIL IPR018453 Prot Inh CR TIL sg IPR006552 VWC out IPR012011 VWF IPR001007 VWF C IPR001846 von Willebrand fac D Tecta (-415.5): gpmDB | homo | protein tectorin alpha [Source:RefSeq peptide;Acc:NP_001100284] IPR000421 Coagulation factor 5/8-type C IPR014853 Conserved-cysteine-rich domain IPR006210 EGF-like IPR013032 EGF-like reg CS IPR001881 EGF Ca bd IPR001507 Endoglin/CD105 IPR017977 Endoglin/CD105 CS IPR003886 NIDO IPR002919 Prot Inh CR TIL IPR018453 Prot Inh CR TIL sg IPR003328 TILa Cysrich IPR006552 VWC out IPR001007 VWF C IPR001846 von Willebrand fac D Pls1 (-396.4): gpmDB | homo | protein plastin 1 (I isoform) [Source:RefSeq peptide;Acc:NP_001101648] IPR001589 Actinin actin-bd CS IPR016146 Calponin-homology IPR001715 Calponin act bd IPR018247 EF HAND 1 IPR018249 EF HAND 2 IPR018248 EF Hand calmodulin IPR002048 EF hand Ca bd IPR000261 EPS15 homology IPR008080 Parvalbumin Tra1 (-340.9): gpmDB | homo | protein Endoplasmin Precursor (Heat shock protein 90 kDa beta member 1)(94 kDa glucose-regulated protein)(GRP-94) Source: UniProtKB/Swiss-Prot Q66HD0 IPR003594 ATP bd ATPase IPR001404 Chaperone htpG IPR019805 Heat shock protein 90 CS IPR020576 Hsp90 C IPR020575 Hsp90 N IPR020568 Ribosomal S5 D2-typ fold IPR004358 Sig transdc His kin-like C ENSRNOP00000016428 (-248.8): gpmDB | homo | protein no description available IPR000048 IQ CaM bd region IPR001609 Myosin head Tuba1b (-228.1): gpmDB | homo | protein tubulin, alpha 1B (Tuba1b), mRNA [Source:RefSeq DNA;Acc:NM_001044270] IPR002452 Alpha tubulin IPR002453 Beta tubulin IPR000158 Cell division FtsZ N IPR002967 Delta tubulin IPR004057 Epsilon tubulin IPR002454 Gamma tubulin IPR008280 Tub FtsZ C IPR000217 Tubulin IPR018316 Tubulin/FtsZ 2-layer-sand-dom IPR017975 Tubulin CS IPR003008 Tubulin FtsZ GTPase IPR019746 Tubulin FtsZ N Fscn2 (-227.1): gpmDB | homo | protein fascin homolog 2, actin-bundling protein, retinal Source: RefSeq_peptide NP_001100542 IPR008999 Actin crosslink IPR010431 Fascin Ptprq (-182.9): gpmDB | homo | protein Phosphotidylinositol phosphatase PTPRQ Precursor (EC 3.1.3.-)(Receptor-type tyrosine-protein phosphatase Q)(R-PTP-Q)(PTP-RQ)(EC 3.1.3.48)(Protein-tyrosine phosphatase receptor-type expressed by glomerular mesangial cells protein 1)(rPTP-GMC1) Source: UniProtKB/Swiss-Prot O88488 IPR003961 FN III IPR008957 Fibronectin typ-III-like fold IPR003962 FnIII subd IPR017996 Royal jelly Anxa5 (-179.4): gpmDB | homo | protein Annexin A5 (Annexin-5)(Annexin V)(Lipocortin V)(Endonexin II)(Calphobindin I)(CBP-I)(Placental anticoagulant protein I)(PAP-I)(Placental anticoagulant protein 4)(PP4)(Thromboplastin inhibitor)(Vascular anticoagulant-alpha)(VAC-alpha)(Anchorin CII) Source: UniProtKB/Swiss-Prot P14668 IPR001464 Annexin IPR002391 AnnexinIV IPR002392 AnnexinV IPR018502 Annexin repeat IPR018252 Annexin repeat CS Alb (-179.3): gpmDB | homo | protein Serum albumin Precursor Source: UniProtKB/Swiss-Prot P02770 IPR001703 Alpha-fetoprotein IPR000264 Serum albumin IPR020858 Serum albumin-like IPR020857 Serum albumin CS IPR014760 Serum albumin N IPR021177 Serum albumin subgroup Pdia4 (-179.1): gpmDB | homo | protein Protein disulfide-isomerase A4 Precursor (EC 5.3.4.1)(Endoplasmic reticulum resident protein 72)(ER protein 72)(ERp-72)(ERp72)(Endoplasmic reticulum resident protein 70)(ER protein 70)(ERp70)(Calcium-binding protein 2)(CaBP2) Source: UniProtKB/Swiss-Prot P38659 IPR001393 Calsequestrin IPR005788 Disulphide isomerase IPR005792 Prot disulphide isomerase IPR017068 Protein diS-isomerase A4 IPR012336 Thioredoxin-like fold IPR006662 Thioredoxin-like subdom IPR017937 Thioredoxin CS IPR013766 Thioredoxin domain ENSRNOP00000036626 (-174.1): gpmDB | homo | protein no description available IPR002110 ANK IPR000694 PRO rich ENSRNOP00000048473 (-171.6): gpmDB |&n