Ontology Collection, GO:0030427y site of polarized growth # accession total log(e) description "1", "YOR326W", "458", "-604.4", "myosin heavy chain, MYO2, establishment of cell polarity (sensu Saccharomyces), microfilament motor activity, actin cap (sensu Fungi)" "2", "YDL126C", "1082", "-603", "microsomal protein of CDC48/PAS1/SEC18 family of ATPases, CDC48, ubiquitin-dependent protein catabolism, ATPase activity, nucleus" "3", "YFL039C", "1413", "-517.5", "actin, ACT1, cell wall organization and biogenesis, structural constituent of cytoskeleton, actin cortical patch (sensu Fungi)" "4", "YIR006C", "303", "-397.3", "actin-cytoskeleton assembly protein, PAN1, endocytosis, protein binding, bridging, plasma membrane" "5", "YMR109W", "318", "-351.3", "myosin I, MYO5, cell wall organization and biogenesis, microfilament motor activity, actin cortical patch (sensu Fungi)" "6", "YBL047C", "428", "-334.2", "similarity to mouse eps15R protein, EDE1, endocytosis, molecular_function unknown, bud neck" "7", "YDR150W", "260", "-322.7", "nuclear migration protein, NUM1, nuclear migration (sensu Saccharomyces), tubulin binding, bud tip" "8", "YNL138W", "607", "-315.6", "adenylate cyclase-associated protein, 70kDa, SRV2, cytoskeleton organization and biogenesis, cytoskeletal protein binding, actin cortical patch (sensu Fungi)" "9", "YDL195W", "589", "-305.2", "component of the COPII coat of ER-golgi vesicles, SEC31, ER to Golgi transport, structural molecule activity, COPII vesicle coat" "10", "YLR058C", "793", "-290.1", "serine hydroxymethyltransferase, cytoplasmic, SHM2, one-carbon compound metabolism, glycine hydroxymethyltransferase activity, cytoplasm" "11", "YJL187C", "9", "-280.7", "ser/tyr dual-specifity protein kinase, SWE1, G2/M transition of mitotic cell cycle, protein kinase activity, nucleus" "12", "YJL157C", "35", "-269.1", "cyclin-dependent kinase inhibitor (CKI), FAR1, signal transduction during conjugation with cellular fusion, cyclin-dependent protein kinase inhibitor activity, cytoplasm" "13", "YCR088W", "681", "-262.8", "actin-binding protein, ABP1, establishment of cell polarity (sensu Saccharomyces), protein binding, cytoplasm" "14", "YLR314C", "327", "-258.7", "cell division control protein, CDC3, cell wall organization and biogenesis, structural constituent of cytoskeleton, shmoo tip" "15", "YPL115C", "68", "-254.3", "GTPase-activating protein for Cdc42p and Rho1p, BEM3, establishment of cell polarity (sensu Saccharomyces), signal transducer activity, intracellular" "16", "YAR019C", "34", "-245.5", "protein kinase of the MAP kinase kinase kinase family, CDC15, protein amino acid phosphorylation, protein kinase activity, bud neck" "17", "YJR076C", "165", "-239.8", "septin, CDC11, cell wall organization and biogenesis, structural constituent of cytoskeleton, shmoo tip" "18", "YCR002C", "214", "-237.8", "cell division control protein, CDC10, cell wall organization and biogenesis, structural constituent of cytoskeleton, septin ring (sensu Saccharomyces)" "19", "YDR129C", "737", "-235.4", "actin filament bundling protein, fimbrin, SAC6, actin filament organization, protein binding, bridging, actin cortical patch (sensu Fungi)" "20", "YMR092C", "368", "-234.4", "actin cytoskeleton component, AIP1, response to osmotic stress, protein binding, cytoplasm" "21", "YHR107C", "339", "-226.9", "septin, CDC12, cell wall organization and biogenesis, structural constituent of cytoskeleton, cytoplasm" "22", "YBL007C", "226", "-187.4", "cytoskeleton assembly control protein, SLA1, cell wall organization and biogenesis, protein binding, bridging, actin cortical patch (sensu Fungi)" "23", "YAL016W", "363", "-184.4", "ser/thr protein phosphatase 2A, regulatory chain A, TPD3, protein biosynthesis, protein phosphatase type 2A activity, cytoplasm" "24", "YER125W", "280", "-184.2", "hect domain E3 ubiquitin-protein ligase, RSP5, protein monoubiquitination, ubiquitin-protein ligase activity, ubiquitin ligase complex" "25", "YNL084C", "121", "-180.2", "required for endocytosis and cytoskeletal organization, END3, actin filament organization, protein binding, bridging, actin cortical patch (sensu Fungi)" "26", "YNL154C", "249", "-178.4", "casein kinase I isoform, YCK2, protein amino acid phosphorylation, casein kinase I activity, plasma membrane" "27", "YCR009C", "325", "-176.5", "similarity to human amphiphysin and Rvs167p, RVS161, endocytosis, cytoskeletal protein binding, actin cortical patch (sensu Fungi)" "28", "YBR017C", "191", "-171.6", "beta-karyopherin, KAP104, protein-nucleus import, nuclear localization sequence binding, cytosol" "29", "YER133W", "460", "-168.7", "ser/thr phosphoprotein phosphatase 1, catalytic chain, GLC7, 35S primary transcript processing, protein phosphatase type 1 activity, nucleolus" "30", "YNR031C", "43", "-166.7", "MAP kinase kinase kinase of the high osmolarity signal transduction pathway, SSK2, protein amino acid phosphorylation, MAP kinase kinase kinase activity, cytosol" "31", "YPR165W", "309", "-163", "GTP-binding protein of the rho subfamily of ras-like proteins, RHO1, cell wall organization and biogenesis, GTPase activity, bud neck" "32", "YGL099W", "273", "-157.1", "Killer toxin REsistant, LSG1, sporulation (sensu Fungi), GTPase activity, cytoplasm" "33", "YJL128C", "56", "-154.8", "tyrosine protein kinase of the MAP kinase kinase family, PBS2, protein amino acid phosphorylation, MAP kinase kinase activity, cytoplasm" "34", "YDR507C", "111", "-153.5", "ser/thr protein kinase, GIN4, protein amino acid phosphorylation, protein kinase activity, bud neck" "35", "YNL106C", "51", "-147.7", "phosphatidylinositol phosphate phosphatase, INP52, cell wall organization and biogenesis, inositol-polyphosphate 5-phosphatase activity, membrane fraction" "36", "YDR388W", "309", "-146.9", "reduced viability upon starvation protein, RVS167, endocytosis, cytoskeletal protein binding, actin cortical patch (sensu Fungi)" "37", "YER120W", "439", "-141.5", "required for inositol metabolism, SCS2, chromatin silencing at telomere, protein binding, endoplasmic reticulum" "38", "YOR122C", "356", "-137.4", "profilin, PFY1, response to osmotic stress, actin monomer binding, contractile ring (sensu Saccharomyces)" "39", "YNL079C", "436", "-135.4", "tropomyosin 1, TPM1, establishment of cell polarity (sensu Saccharomyces), actin lateral binding, contractile ring (sensu Saccharomyces)" "40", "YDL225W", "133", "-126.3", "septin, SHS1, establishment of cell polarity (sensu Saccharomyces), structural constituent of cytoskeleton, septin ring" "41", "YPL032C", "143", "-120.5", "strong similarity to Pam1p, SVL3, endocytosis, molecular_function unknown, cytoplasm" "42", "YBR109C", "443", "-118.4", "calmodulin, CMD1, cytoskeleton organization and biogenesis, calcium ion binding, cytoplasm" "43", "YBR130C", "89", "-117.4", "required for mother cell-specific expression of HO, SHE3, mRNA localization, intracellular, mRNA binding, cytoplasm" "44", "YOR046C", "485", "-114.1", "RNA helicase, DBP5, mRNA-nucleus export, RNA helicase activity, cytoplasm" "45", "YHR098C", "214", "-113.4", "similarity to human hypothetical protein, SFB3, ER to Golgi transport, molecular_function unknown, endoplasmic reticulum" "46", "YPL111W", "369", "-111.2", "arginase, CAR1, arginine catabolism to ornithine, arginase activity, cytosol" "47", "YNL243W", "314", "-107.2", "cytoskeleton assembly control protein, SLA2, cell wall organization and biogenesis, protein binding, bridging, actin cortical patch (sensu Fungi)" "48", "YBR080C", "304", "-107", "vesicular-fusion protein, functional homolog of NSF, SEC18, ER to Golgi transport, ATPase activity, cytoplasm" "49", "YGL106W", "427", "-104.9", "Myo2p light chain, MLC1, establishment of cell polarity (sensu Saccharomyces), microfilament motor activity, actin cap (sensu Fungi)" "50", "YIL034C", "173", "-104.2", "F-actin capping protein, beta subunit, CAP2, cell wall organization and biogenesis, protein binding, actin cortical patch (sensu Fungi)" "51", "YLR206W", "127", "-101.7", "clathrin binding protein, required for endocytosis, ENT2, actin filament organization, clathrin binding, actin cortical patch (sensu Fungi)" "52", "YLR330W", "178", "-96.7", "chitin synthesis protein, CHS5, conjugation with cellular fusion, molecular_function unknown, cytoplasm" "53", "YLR084C", "23", "-91", "weak similarity to Pst1p, RAX2, bud site selection, molecular_function unknown, membrane" "54", "YPR119W", "29", "-89.6", "cyclin, G2/M-specific, CLB2, G2/M transition of mitotic cell cycle, cyclin-dependent protein kinase regulator activity, cytoplasm" "55", "YBL085W", "64", "-87.5", "BEM1 protein-binding protein, BOI1, establishment of cell polarity (sensu Saccharomyces), phospholipid binding, bud neck" "56", "YLL021W", "150", "-86.2", "involved in cell polarity, SPA2, establishment of cell polarity (sensu Saccharomyces), cytoskeletal regulatory protein binding, bud neck" "57", "YIR003W", "78", "-84.9", "weak similarity to mammalian neurofilament triplet H proteins, biological_process unknown, molecular_function unknown, actin cytoskeleton" "58", "YCR030C", "166", "-84.6", "weak similarity to S.pombe hypothetical protein SPBC4C3.06, SYP1, biological_process unknown, molecular_function unknown, bud neck" "59", "YMR001C", "21", "-81.9", "protein kinase, involved in regulation of DNA replication, CDC5, protein amino acid phosphorylation, protein serine/threonine kinase activity, nucleus" "60", "YBR160W", "166", "-78.9", "cyclin-dependent protein kinase, CDC28, protein amino acid phosphorylation, cyclin-dependent protein kinase activity, cytoplasm" "61", "YDL135C", "127", "-77.8", "rho GDP dissociation inhibitor with activity toward Rho1p, RDI1, actin filament organization, signal transducer activity, cytosol" "62", "YFR024C-A", "156", "-76.4", "possible role in the regulation of actin cytoskeletal organization, LSB3, actin filament organization, molecular_function unknown, cytoplasm" "63", "YOR239W", "154", "-74.7", "questionable ORF, ABP140, actin cytoskeleton organization and biogenesis, protein binding, bridging, actin filament" "64", "YBR059C", "105", "-74.3", "Ark-family Kinase-Like protein, AKL1, actin cytoskeleton organization and biogenesis, protein kinase activity, cytoplasm" "65", "YPL249C", "89", "-71.3", "similarity to mouse Tbc1 protein, GYP5, vesicle-mediated transport, Rab GTPase activator activity, cytosol" "66", "YHR023W", "62", "-70.1", "myosin-1 isoform (type II myosin) heavy chain, MYO1, response to osmotic stress, microfilament motor activity, contractile ring (sensu Saccharomyces)" "67", "YJR090C", "18", "-70", "required for glucose repression and for glucose and cation transport, GRR1, ubiquitin-dependent protein catabolism, protein binding, cytoplasm" "68", "YGR092W", "27", "-69.8", "ser/thr protein kinase related to Dbf20p, DBF2, protein amino acid phosphorylation, protein serine/threonine kinase activity, bud neck" "69", "YJR092W", "39", "-69.8", "budding protein, BUD4, bud site selection, GTP binding, contractile ring (sensu Saccharomyces)" "70", "YKL007W", "175", "-69.4", "F-actin capping protein alpha subunit, CAP1, cell wall organization and biogenesis, protein binding, actin cortical patch (sensu Fungi)" "71", "YDL159W", "32", "-67.2", "ser/thr/tyr protein kinase of MAP kinase kinase family, STE7, protein amino acid phosphorylation, MAP kinase kinase activity, cytoplasm" "72", "YHR114W", "77", "-66.4", "similarity to S.pombe hypothetical protein and human protein-tyrosine kinase fer, BZZ1, actin filament organization, molecular_function unknown, cytoplasm" "73", "YPL204W", "65", "-66", "casein kinase I, ser/thr/tyr protein kinase, HRR25, DNA repair, protein kinase activity, nucleus" "74", "YIL138C", "214", "-63.3", "tropomyosin, isoform 2, TPM2, establishment of cell polarity (sensu Saccharomyces), actin lateral binding, contractile ring (sensu Saccharomyces)" "75", "YFL034C-B", "26", "-63", "required for maintenance in ploidy, MOB2, protein amino acid phosphorylation, protein kinase activator activity, nucleus" "76", "YHR158C", "170", "-62.4", "involved in cell fusion and morphology, KEL1, cellular morphogenesis, molecular_function unknown, cytoplasm" "77", "YHL007C", "104", "-62.4", "ser/thr protein kinase of the pheromone pathway, STE20, protein amino acid phosphorylation, protein serine/threonine kinase activity, shmoo tip" "78", "YDL019C", "70", "-62.1", "similarity to Swh1p, OSH2, steroid biosynthesis, oxysterol binding, plasma membrane" "79", "YIL129C", "73", "-62", "Transcriptional Activator of OCH1, TAO3, cellular morphogenesis, molecular_function unknown, shmoo tip" "80", "YDL161W", "70", "-60.4", "clathrin binding protein, required for endocytosis, ENT1, actin filament organization, clathrin binding, actin cortical patch (sensu Fungi)" "81", "YKL126W", "150", "-59.9", "ser/thr-specific protein kinase, YPK1, protein amino acid phosphorylation, protein serine/threonine kinase activity, plasma membrane" "82", "YDR348C", "121", "-59.7", "similarity to hypothetical protein YHR097c, biological_process unknown, molecular_function unknown, bud neck" "83", "YHR030C", "105", "-57.9", "ser/thr protein kinase of MAP kinase family, SLT2, cell wall organization and biogenesis, MAP kinase activity, cytoplasm" "84", "YGR080W", "113", "-55.9", "twinfilin, an actin monomer sequestering protein, TWF1, polar budding, actin monomer binding, actin cortical patch (sensu Fungi)" "85", "YOR094W", "29", "-54.7", "ADP-ribosylation factor 3, ARF3, intracellular protein transport, GTPase activity, cellular_component unknown" "86", "YOR127W", "38", "-54", "RHO-type GTPase-activating protein for Cdc42p, RGA1, establishment of cell polarity (sensu Saccharomyces), signal transducer activity, intracellular" "87", "YKL130C", "50", "-53.7", "required for mother cell-specific expression of HO, SHE2, mRNA localization, intracellular, mRNA binding, cytoplasm" "88", "YBR133C", "18", "-51.1", "adapter in a regulatory pathway that relieves tyrosine phosphorylation of Cdc28, HSL7, G2/M transition of mitotic cell cycle, protein-arginine N-methyltransferase activity, bud neck" "89", "YMR295C", "117", "-51.1", "similarity to YGR273c, biological_process unknown, molecular_function unknown, bud" "90", "YOR014W", "121", "-50.5", "potential regulatory subunit of protein phosphatase 2A, RTS1, protein biosynthesis, protein phosphatase type 2A activity, cytoplasm" "91", "YLR319C", "52", "-50.4", "bud site selection protein, BUD6, establishment of cell polarity (sensu Saccharomyces), cytoskeletal regulatory protein binding, actin cap (sensu Fungi)" "92", "YCR017C", "57", "-50.2", "putative sensor/transporter protein, CWH43, cell wall organization and biogenesis, molecular_function unknown, bud neck" "93", "YFL047W", "67", "-50", "GTPase activating protein, RGD2, small GTPase mediated signal transduction, Rho GTPase activator activity, cytoplasm" "94", "YNL166C", "54", "-49.5", "similarity to S. pombe SPBC1711.05 serine-rich repeat protein of unknown function, BNI5, cytokinesis, molecular_function unknown, bud neck" "95", "YER114C", "69", "-48.8", "budding protein, BOI2, establishment of cell polarity (sensu Saccharomyces), phospholipid binding, bud neck" "96", "YJL085W", "37", "-47.3", "70 kDa exocyst component protein, EXO70, cytokinesis, protein binding, exocyst" "97", "YGR229C", "96", "-45.8", "beta-1, 3-glucan synthesis protein, SMI1, cell wall organization and biogenesis, molecular_function unknown, nucleus" "98", "YGR152C", "83", "-44.8", "GTP-binding protein, RSR1, bud site selection, GTPase activity, plasma membrane" "99", "YBL105C", "54", "-40.6", "ser/thr protein kinase, PKC1, cell wall organization and biogenesis, protein kinase C activity, site of polarized growth (sensu Saccharomyces)" "100", "YNL272C", "28", "-40.4", "protein transport protein, SEC2, exocytosis, guanyl-nucleotide exchange factor activity, cytosol" "101", "YHR149C", "25", "-39.8", "similarity to hypothetical protein YGR221c, SKG6, biological_process unknown, molecular_function unknown, bud neck" "102", "YIL159W", "47", "-38.5", "regulator of budding, BNR1, actin filament organization, cytoskeletal protein binding, contractile ring (sensu Saccharomyces)" "103", "YBR023C", "45", "-38.4", "chitin synthase III, CHS3, response to osmotic stress, chitin synthase activity, contractile ring (sensu Saccharomyces)" "104", "YMR192W", "49", "-38", "similarity to mouse Tbc1 protein, APP2, actin filament organization, molecular_function unknown, cytoplasm" "105", "YLR332W", "22", "-37.4", "mating process protein, MID2, cell wall organization and biogenesis, transmembrane receptor activity, integral to plasma membrane" "106", "YLR166C", "66", "-37", "required for exocytosis, SEC10, establishment of cell polarity (sensu Saccharomyces), protein binding, exocyst" "107", "YOR233W", "18", "-36.9", "ser/thr protein kinase, KIN4, biological_process unknown, protein kinase activity, cytoplasm" "108", "YDL240W", "38", "-36.1", "GTPase-activating protein of the rho/rac family, LRG1, small GTPase mediated signal transduction, Rho GTPase activator activity, cytoplasm" "109", "YLR229C", "137", "-36", "GTP-binding protein of RAS superfamily, CDC42, establishment of cell polarity (sensu Saccharomyces), GTPase activity, plasma membrane" "110", "YNL271C", "57", "-35.4", "regulator of budding, BNI1, establishment of cell polarity (sensu Saccharomyces), cytoskeletal regulatory protein binding, bud neck" "111", "YDR164C", "124", "-35", "protein transport protein, SEC1, vesicle fusion, SNARE binding, bud neck" "112", "YIL140W", "13", "-34.8", "required for axial pattern of budding, AXL2, bud site selection, molecular_function unknown, bud neck" "113", "YGL190C", "100", "-34.4", "ser/thr phosphatase 2A regulatory subunit B, CDC55, protein biosynthesis, protein phosphatase type 2A activity, nucleus" "114", "YBR102C", "50", "-32.3", "exocyst protein essential for secretion, EXO84, exocytosis, protein binding, bud neck" "115", "YLR337C", "81", "-30.6", "verprolin, VRP1, actin filament organization, actin binding, actin cortical patch (sensu Fungi)" "116", "YKL189W", "12", "-29.9", "similarity to mouse hypothetical calcium-binding protein and D.melanogaster Mo25 gene, HYM1, cytokinesis, completion of separation, transcriptional repressor activity, intracellular" "117", "YCL014W", "109", "-29.9", "budding protein, BUD3, cytokinesis, molecular_function unknown, contractile ring (sensu Saccharomyces)" "118", "YLR353W", "17", "-29.6", "budding protein, BUD8, pseudohyphal growth, molecular_function unknown, bud tip" "119", "YER008C", "70", "-29.6", "component of exocyst complex, SEC3, cytokinesis, protein binding, exocyst" "120", "YEL040W", "154", "-29", "cell wall protein, UTR2, cell wall organization and biogenesis, molecular_function unknown, cell wall (sensu Fungi)" "121", "YBR260C", "34", "-29", "similarity to C.elegans GTPase-activating protein, RGD1, osmosensory signaling pathway, Rho GTPase activator activity, actin cortical patch (sensu Fungi)" "122", "YIL068C", "28", "-28.3", "protein transport protein, SEC6, cytokinesis, protein binding, bud tip" "123", "YLR187W", "44", "-28.3", "similarity to hypothetical protein YNL278w, SKG3, biological_process unknown, molecular_function unknown, cytoplasm" "124", "YBL061C", "32", "-28.2", "protoplast regeneration and killer toxin resistance protein, SKT5, response to osmotic stress, enzyme activator activity, contractile ring (sensu Saccharomyces)" "125", "YNR052C", "36", "-27.8", "required for glucose derepression, POP2, regulation of transcription from Pol II promoter, 3'-5'-exoribonuclease activity, cytoplasm" "126", "YNL020C", "33", "-27.7", "Actin Regulating Kinase, ARK1, protein amino acid phosphorylation, protein serine/threonine kinase activity, actin cortical patch (sensu Fungi)" "127", "YKL101W", "56", "-27.6", "ser/thr protein kinase, coupling septin ring assembly to cell cycle progression, HSL1, protein amino acid phosphorylation, protein kinase activity, bud neck" "128", "YJL158C", "194", "-27.2", "strong similarity to Pir1p/Hsp150p/Pir3p family, CIS3, cell wall organization and biogenesis, structural constituent of cell wall, plasma membrane" "129", "YGR014W", "34", "-26.9", "multicopy suppressor of a cdc24 bud emergence defect, MSB2, establishment of cell polarity (sensu Saccharomyces), osmosensor activity, integral to plasma membrane" "130", "YGR238C", "27", "-26.9", "involved in cell fusion and morphogenesis, KEL2, conjugation with cellular fusion, molecular_function unknown, bud neck" "131", "YDR251W", "75", "-26.7", "coiled-coil protein multicopy suppressor of loss of PP2A, PAM1, pseudohyphal growth, molecular_function unknown, bud neck" "132", "YPR055W", "45", "-26.1", "protein transport protein, SEC8, cytokinesis, protein binding, bud tip" "133", "YDR166C", "25", "-26", "required for exocytosis, SEC5, cytokinesis, protein binding, exocyst" "134", "YOR301W", "16", "-25.7", "similarity to S. pombe SPAC23G3.05c, RAX1, bud site selection, molecular_function unknown, bud neck" "135", "YER149C", "27", "-25.6", "involved in oriented growth toward mating partner, PEA2, establishment of cell polarity (sensu Saccharomyces), cytoskeletal regulatory protein binding, actin cap (sensu Fungi)" "136", "YCL024W", "42", "-25.5", "kinase coordinate cell cycle progression with the organization of the peripheralcytoskeleton, KCC4, protein amino acid phosphorylation, protein kinase activity, bud neck" "137", "YJL095W", "46", "-25.4", "ser/thr protein kinase of the MEKK family, BCK1, protein amino acid phosphorylation, MAP kinase kinase kinase activity, intracellular" "138", "YAR014C", "28", "-25", "protein involved in bud-site selection, BUD14, cellular morphogenesis during vegetative growth, molecular_function unknown, bud neck" "139", "YGL233W", "40", "-24.9", "vesicular traffic control protein, SEC15, cytokinesis, protein binding, bud tip" "140", "YNL293W", "9", "-24.6", "similarity to Mic1p and human transforming protein tre-2, and strong similarity to YOL112w, MSB3, actin filament organization, Rab GTPase activator activity, bud tip" "141", "YPL269W", "24", "-24.5", "cortical protein required for cytoplasmic microtubule orientation and nuclear migration, KAR9, nuclear migration (sensu Saccharomyces), molecular_function unknown, shmoo tip" "142", "YNL161W", "19", "-22.2", "strong similarity to U.maydis Ukc1p protein kinase, CBK1, cellular morphogenesis during conjugation with cellular fusion, protein kinase activity, cytoplasm" "143", "YMR032W", "13", "-21.3", "involved in cytokinesis, HOF1, cytokinesis, cytoskeletal protein binding, contractile ring (sensu Saccharomyces)" "144", "YOR008C", "26", "-21.1", "required for cell wall integrity and for stress response, SLG1, cell wall organization and biogenesis, transmembrane receptor activity, membrane fraction" "145", "YDL117W", "24", "-21.1", "similarity to hypothetical S. pombe protein, protein possibly involved in cytokinesis, CYK3, cytokinesis, molecular_function unknown, cytoplasm" "146", "YOR181W", "15", "-20.9", "component of actin cortical patches, LAS17, actin filament organization, cytoskeletal protein binding, cytoplasm" "147", "YPL116W", "30", "-20.7", "similarity to Hos1p, Hos2p, Hos3p, Rpd3p and human histone deacetylase HD1, HOS3, histone deacetylation, histone deacetylase activity, cytoplasm" "148", "YDR379W", "30", "-19.5", "similarity to Dbm1p and to the rat GAP-associated protein p190, RGA2, establishment of cell polarity (sensu Saccharomyces), signal transducer activity, intracellular" "149", "YOR264W", "13", "-19", "hypothetical protein, DSE3, biological_process unknown, molecular_function unknown, bud neck" "150", "YLR371W", "75", "-19", "GDP/GTP exchange factor for Rho1p, ROM2, cell wall organization and biogenesis, signal transducer activity, bud tip" "151", "YBL060W", "7", "-18.3", "weak similarity to probable guanine nucleotide exchange factor, S.pombe, biological_process unknown, molecular_function unknown, cytoplasm" "152", "YPL221W", "29", "-18.2", "strong similarity to YGL139w and YAL053w, BOP1, biological_process unknown, molecular_function unknown, bud neck" "153", "YIL095W", "20", "-17.9", "serine/threonine protein kinase involved in regulation of actin cytoskeleton organization, PRK1, protein amino acid phosphorylation, protein serine/threonine kinase activity, actin cortical patch (sensu Fungi)" "154", "YOL070C", "48", "-17.8", "hypothetical protein, biological_process unknown, molecular_function unknown, cytoplasm" "155", "YGR041W", "17", "-17.6", "budding protein, BUD9, bud site selection, molecular_function unknown, bud neck" "156", "YHR102W", "39", "-17", "ser/thr protein kinase that interacts with Cdc31p, KIC1, cell wall organization and biogenesis, kinase activity, cytoplasm" "157", "YKR090W", "33", "-16.8", "similarity to chicken Lim protein kinase and Islet proteins, PXL1, maintenance of cell polarity (sensu Fungi), protein binding, cytoplasm" "158", "YIL106W", "29", "-16.7", "required for completion of mitosis and maintenance of ploidy, MOB1, protein amino acid phosphorylation, kinase regulator activity, bud neck" "159", "YPR188C", "25", "-16.6", "regulatory light chain (RLC) for Myo1p, is involved in Myo1p ringdisassembly, MLC2, cytokinesis, contractile ring contraction, myosin II binding, contractile ring (sensu Saccharomyces)" "160", "YKL209C", "17", "-16.2", "^Full-size^ ABC transporter responsible for export of the ^a^ factor mating pheromone, STE6, peptide pheromone export, ATPase activity, coupled to transmembrane movement of substances, shmoo tip" "161", "YAL041W", "20", "-15.6", "GTP/GDP exchange factor for Cdc42p, CDC24, establishment of cell polarity (sensu Saccharomyces), signal transducer activity, nucleus" "162", "YOR188W", "41", "-15.2", "morphogenesis-related protein, MSB1, establishment of cell polarity (sensu Saccharomyces), molecular_function unknown, bud neck" "163", "YBL016W", "108", "-13.9", "mitogen-activated protein kinase (MAP kinase), FUS3, protein amino acid phosphorylation, MAP kinase activity, cytoplasm" "164", "YOR353C", "32", "-12.9", "weak similarity to adenylate cyclases, SOG2, biological_process unknown, molecular_function unknown, cytoplasm" "165", "YBR200W", "31", "-12.8", "bud emergence mediator, BEM1, establishment of cell polarity (sensu Saccharomyces), protein binding, bud neck" "166", "YKL079W", "40", "-12.8", "kinesin-related protein, SMY1, exocytosis, motor activity, bud neck" "167", "YER032W", "11", "-12.5", "interacts with the poly(A) polymerase in the two hybrid system, FIR1, mRNA polyadenylylation, molecular_function unknown, bud neck" "168", "YER071C", "5", "-12.5", "hypothetical protein, biological_process unknown, molecular_function unknown, cytoplasm" "169", "YBR038W", "14", "-12.4", "chitin synthase II, CHS2, response to osmotic stress, chitin synthase activity, contractile ring (sensu Saccharomyces)" "170", "YNL233W", "21", "-12.2", "bud neck involved, BNI4, cytokinesis, protein binding, contractile ring (sensu Saccharomyces)" "171", "YPR171W", "43", "-11.7", "hypothetical protein, BSP1, actin cytoskeleton organization and biogenesis, molecular_function unknown, bud neck" "172", "YLR190W", "25", "-11.1", "protein localized to bud sites and tips, mother-bud junction, MMR1, biological_process unknown, molecular_function unknown, bud neck" "173", "YDL146W", "96", "-10.4", "weak similarity to Orc3p, biological_process unknown, molecular_function unknown, cytoplasm" "174", "YDL212W", "28", "-10.1", "endoplasmatic reticulum membrane protein, SHR3, ER to Golgi transport, unfolded protein binding, integral to endoplasmic reticulum membrane" "175", "YPR122W", "28", "-9.9", "protease, AXL1, bud site selection, metalloendopeptidase activity, integral to membrane" "176", "YNL304W", "7", "-9.5", "similarity to Ypt1p and rab GTP-binding proteins, YPT11, mitochondrion inheritance, GTPase activity, bud neck" "177", "YOL112W", "8", "-9.4", "similarity to Mic1p and human transforming protein tre-2, MSB4, actin filament organization, Rab GTPase activator activity, bud tip" "178", "YMR273C", "25", "-9", "involved in negative regulation of cell polarity, ZDS1, establishment of cell polarity (sensu Saccharomyces), protein binding, cytoplasm" "179", "YDR103W", "42", "-8.2", "pheromone signal transduction pathway protein, STE5, signal transduction during conjugation with cellular fusion, MAP-kinase scaffold activity, cytoplasm" "180", "YPL066W", "7", "-7.8", "hypothetical protein, biological_process unknown, molecular_function unknown, cytoplasm" "181", "YKR100C", "15", "-7.8", "similarity to hypothetical protein YIL158w, SKG1, biological_process unknown, molecular_function unknown, bud" "182", "YPL242C", "29", "-7.3", "involved in cytokinesis, has similarity to mammalian IQGAP proteins, IQG1, actin filament organization, cytoskeletal protein binding, contractile ring (sensu Saccharomyces)" "183", "YOR231W", "11", "-7.1", "ser/thr protein kinase, MKK1, protein amino acid phosphorylation, MAP kinase kinase activity, bud tip" "184", "YDL179W", "14", "-6.4", "cyclin like protein interacting with Pho85p, PCL9, cell cycle, cyclin-dependent protein kinase regulator activity, cyclin-dependent protein kinase holoenzyme complex" "185", "YJL204C", "13", "-6.1", "involved in recycling of the SNARE Snc1p , RCY1, endocytosis, protein binding, site of polarized growth (sensu Saccharomyces)" "186", "YBR040W", "15", "-5.7", "required for efficient mating, FIG1, cellular morphogenesis during conjugation with cellular fusion, molecular_function unknown, cell wall (sensu Fungi)" "187", "YNL283C", "6", "-5.6", "glucoamylase III (alpha-1, 4-glucan-glucosidase), WSC2, cell wall organization and biogenesis, transmembrane receptor activity, cytoplasm" "188", "YOR304C-A", "1", "-5.1", "similarity to mouse apolipoprotein A-IV precursor, biological_process unknown, molecular_function unknown, cytoplasm" "189", "YCL027W", "7", "-4.9", "cell fusion protein, FUS1, conjugation with cellular fusion, molecular_function unknown, plasma membrane" "190", "YNL152W", "22", "-4.5", "similarity to hypothetical protein S. pombe, biological_process unknown, phospholipid binding, cytoplasm" "191", "YER124C", "8", "-4.3", "weak similarity to Dictyostelium WD40 repeat protein 2, DSE1, cell wall organization and biogenesis, molecular_function unknown, bud neck" "192", "YER118C", "4", "-4", "involved in the HOG1 high-osmolarity signal transduction pathway, SHO1, pseudohyphal growth, osmosensor activity, plasma membrane" "193", "YDR309C", "8", "-3.2", "Cdc42 GTPase-binding protein, GIC2, establishment of cell polarity (sensu Saccharomyces), small GTPase regulatory/interacting protein activity, bud tip" "194", "YNL279W", "16", "-3.1", "similarity to S. pombe coiled-coil protein of unknown function, PRM1, plasma membrane fusion, molecular_function unknown, integral to membrane" "195", "YKL048C", "7", "-3", "ser/thr-specific protein kinase, ELM1, protein amino acid phosphorylation, protein serine/threonine kinase activity, contractile ring (sensu Saccharomyces)" "196", "YLR313C", "8", "-2.7", "required for bipolar bud site selection, SPH1, establishment of cell polarity (sensu Saccharomyces), cytoskeletal regulatory protein binding, bud neck" "197", "YNL078W", "11", "-2.6", "non-essential role in the mitotic signaling network, NIS1, regulation of mitosis, molecular_function unknown, nucleus" "198", "YOL105C", "5", "-2.6", "cell wall integrity and stress response component 3, WSC3, cell wall organization and biogenesis, transmembrane receptor activity, membrane fraction" "199", "YGR221C", "6", "-2.3", "Target of SBF, localizes to the bud neck and budtip, TOS2, biological_process unknown, molecular_function unknown, bud neck" "200", "YGR058W", "3", "-2.2", "similarity to mouse calcium-binding protein, biological_process unknown, molecular_function unknown, cytoplasm" "201", "YBL031W", "6", "-2.2", "hypothetical protein, SHE1, biological_process unknown, molecular_function unknown, microtubule cytoskeleton" "202", "YMR232W", "8", "-2.1", "required for cell fusion during mating, FUS2, plasma membrane fusion, molecular_function unknown, shmoo tip" "203", "YDR218C", "8", "-2.1", "septin-related sporulation protein, SPR28, cell wall organization and biogenesis, structural constituent of cytoskeleton, septin ring (sensu Saccharomyces)" "204", "YPL158C", "8", "-1.8", "weak similarity to human nucleolin, biological_process unknown, molecular_function unknown, bud neck" "205", "YOR129C", "7", "-1.7", "weak similarity to hypothetical protein SPBC776.06c S. pombe, response to drug, structural constituent of cytoskeleton, cytoplasm" "206", "YCR038C", "7", "-1.6", "GDP/GTP exchange factor for Rsr1p/Bud1p, BUD5, pseudohyphal growth, signal transducer activity, bud neck" "207", "YER144C", "10", "-1.6", "ubiquitin-specific protease, UBP5, protein deubiquitination, ubiquitin-specific protease activity, cytoplasm" "208", "YDL127W", "7", "-1.5", "cyclin, G1/S-specific, PCL2, cell cycle, cyclin-dependent protein kinase regulator activity, cyclin-dependent protein kinase holoenzyme complex" "209", "YGR059W", "6", "-1.5", "sporulation-specific septin, SPR3, cell wall organization and biogenesis, structural constituent of cytoskeleton, prospore membrane" "210", "YOL007C", "4", "-1.4", "involved in chitin synthesis, biological_process unknown, molecular_function unknown, vacuole (sensu Fungi)" "211", "YHR061C", "3", "-1.2", "Cdc42 GTPase-binding protein, GIC1, establishment of cell polarity (sensu Saccharomyces), small GTPase regulatory/interacting protein activity, bud neck" "212", "YCR043C", "1", "-1.1", "hypothetical protein, biological_process unknown, molecular_function unknown, Golgi apparatus" out of 213