| # |
accession |
total |
log(e) |
description |
| 1. |
YPL231W |
1586 |
-1842.9 |
fatty-acyl-CoA synthase, alpha chain, FAS2, fatty acid biosynthesis, holo-[acyl-carrier protein] synthase activity, fatty-acid synthase complex |
| 2. |
YKL182W |
1725 |
-1621.3 |
fatty-acyl-CoA synthase, beta chain, FAS1, fatty acid biosynthesis, [acyl-carrier protein] S-malonyltransferase activity, cytosol |
| 3. |
YNR016C |
1492 |
-907.8 |
acetyl-CoA carboxylase, ACC1, protein-nucleus import, acetyl-CoA carboxylase activity, cytosol |
| 4. |
YML008C |
968 |
-404 |
S-adenosyl-methionine delta-24-sterol-c-methyltransferase, ERG6, ergosterol biosynthesis, sterol 24-C-methyltransferase activity, endoplasmic reticulum |
| 5. |
YKL212W |
598 |
-388.7 |
recessive suppressor of secretory defect, SAC1, dephosphorylation, inositol or phosphatidylinositol phosphatase activity, integral to endoplasmic reticulum membrane |
| 6. |
YNL123W |
223 |
-382.5 |
weak similarity to C.jejuni serine protease, biological_process unknown, serine-type peptidase activity, nucleus |
| 7. |
YHR042W |
596 |
-369.4 |
NADPH-cytochrome P450 reductase, NCP1, ergosterol biosynthesis, electron transporter activity, microsome |
| 8. |
YOR317W |
889 |
-312.6 |
long-chain-fatty-acid--CoA ligase, FAA1, lipid metabolism, long-chain-fatty-acid-CoA ligase activity, lipid particle |
| 9. |
YPL028W |
1138 |
-283.9 |
acetyl-CoA C-acetyltransferase, cytosolic, ERG10, ergosterol biosynthesis, acetyl-CoA C-acetyltransferase activity, cytosol |
| 10. |
YLR347C |
646 |
-268.8 |
karyopherin-beta, KAP95, protein-nucleus import, protein carrier activity, cytoplasm |
| 11. |
YBR177C |
403 |
-262.1 |
alcohol acyl transferase, EHT1, lipid metabolism, serine hydrolase activity, lipid particle |
| 12. |
YJR073C |
103 |
-231.2 |
methylene-fatty-acyl-phospholipid synthase, OPI3, phosphatidylcholine biosynthesis, phosphatidyl-N-methylethanolamine N-methyltransferase activity, endoplasmic reticulum |
| 13. |
YMR079W |
686 |
-225.3 |
phosphatidylinositol(PI)/phosphatidylcholine(PC) transfer protein, SEC14, Golgi to plasma membrane transport, phosphatidylinositol transporter activity, cytosol |
| 14. |
YBR159W |
304 |
-225 |
similarity to human 17-beta-hydroxysteroid dehydrogenase, fatty acid elongation, ketoreductase activity, endoplasmic reticulum |
| 15. |
YKL150W |
444 |
-216.5 |
cytochrome-b5 reductase, MCR1, response to oxidative stress, cytochrome-b5 reductase activity, mitochondrial outer membrane |
| 16. |
YGL205W |
59 |
-216 |
acyl-CoA oxidase, POX1, fatty acid beta-oxidation, acyl-CoA oxidase activity, peroxisomal matrix |
| 17. |
YLR305C |
144 |
-212.2 |
phosphatidylinositol-4-kinase, STT4, actin cytoskeleton organization and biogenesis, 1-phosphatidylinositol 4-kinase activity, plasma membrane |
| 18. |
YMR296C |
216 |
-211.7 |
serine C-palmitoyltransferase subunit, LCB1, sphingolipid biosynthesis, serine C-palmitoyltransferase activity, membrane fraction |
| 19. |
YDL078C |
509 |
-205.9 |
malate dehydrogenase, peroxisomal, MDH3, fatty acid beta-oxidation, malic enzyme activity, peroxisomal matrix |
| 20. |
YGR157W |
296 |
-205.5 |
phosphatidylethanolamine N-methyltransferase, CHO2, phosphatidylcholine biosynthesis, phosphatidylethanolamine N-methyltransferase activity, endoplasmic reticulum |
| 21. |
YDR294C |
267 |
-199.4 |
dihydrosphingosine phosphate lyase, DPL1, sphingolipid metabolism, sphinganine-1-phosphate aldolase activity, endoplasmic reticulum |
| 22. |
YAL013W |
39 |
-198.6 |
regulator of phospholipid metabolism, DEP1, regulation of transcription from Pol II promoter, molecular_function unknown, cellular_component unknown |
| 23. |
YDR434W |
119 |
-194.9 |
similarity to S.pombe hypothetical protein, GPI17, attachment of GPI anchor to protein, GPI-anchor transamidase activity, integral to endoplasmic reticulum membrane |
| 24. |
YHR190W |
424 |
-191.3 |
farnesyl-diphosphate farnesyltransferase, ERG9, ergosterol biosynthesis, farnesyl-diphosphate farnesyltransferase activity, endoplasmic reticulum |
| 25. |
YBL039C |
781 |
-188.2 |
CTP synthase 1, URA7, phospholipid biosynthesis, CTP synthase activity, cytosol |
| 26. |
YER125W |
379 |
-184.2 |
hect domain E3 ubiquitin-protein ligase, RSP5, protein monoubiquitination, ubiquitin-protein ligase activity, ubiquitin ligase complex |
| 27. |
YER015W |
53 |
-182.2 |
long-chain-fatty-acid--CoA ligase, FAA2, lipid metabolism, long-chain-fatty-acid-CoA ligase activity, peroxisome |
| 28. |
YKR009C |
54 |
-181.9 |
hydratase-dehydrogenase-epimerase, peroxisomal, FOX2, fatty acid beta-oxidation, 3-hydroxyacyl-CoA dehydrogenase activity, peroxisomal matrix |
| 29. |
YJL167W |
966 |
-181 |
farnesyl-pyrophosphate synthetase, ERG20, ergosterol biosynthesis, dimethylallyltranstransferase activity, cytosol |
| 30. |
YIL124W |
149 |
-181 |
1-Acyldihydroxyacetone-phosphate reductase, AYR1, phosphatidic acid biosynthesis, acylglycerone-phosphate reductase activity, cytoplasm |
| 31. |
YPR183W |
605 |
-177.1 |
dolichyl-phosphate beta-D-mannosyltransferase, DPM1, N-linked glycosylation, transferase activity, transferring glycosyl groups, endoplasmic reticulum |
| 32. |
YML126C |
863 |
-169.2 |
3-hydroxy-3-methylglutaryl coenzyme A synthase, ERG13, ergosterol biosynthesis, hydroxymethylglutaryl-CoA synthase activity, mitochondrion |
| 33. |
YJR103W |
300 |
-165.2 |
CTP synthase 2, URA8, phospholipid biosynthesis, CTP synthase activity, cytosol |
| 34. |
YKR067W |
147 |
-162.8 |
strong similarity to Sct1p, GPT2, phospholipid biosynthesis, glycerol-3-phosphate O-acyltransferase activity, cytoplasm |
| 35. |
YKL165C |
179 |
-160.3 |
sporulation protein, MCD4, GPI anchor biosynthesis, molecular_function unknown, cell wall (sensu Fungi) |
| 36. |
YER120W |
655 |
-150.8 |
required for inositol metabolism, SCS2, chromatin silencing at telomere, protein binding, endoplasmic reticulum |
| 37. |
YNR043W |
658 |
-149.2 |
mevalonate pyrophosphate decarboxylase, MVD1, ergosterol biosynthesis, diphosphomevalonate decarboxylase activity, cytosol |
| 38. |
YOR175C |
178 |
-147.8 |
similarity to human and murine C3f protein, biological_process unknown, molecular_function unknown, endoplasmic reticulum |
| 39. |
YNL106C |
65 |
-147.7 |
phosphatidylinositol phosphate phosphatase, INP52, cell wall organization and biogenesis, inositol-polyphosphate 5-phosphatase activity, membrane fraction |
| 40. |
YBR035C |
444 |
-144.7 |
pyridoxamine-phosphate oxidase, PDX3, fatty acid metabolism, pyridoxamine-phosphate oxidase activity, cellular_component unknown |
| 41. |
YHR007C |
468 |
-140.8 |
cytochrome P450 lanosterol 14a-demethylase, ERG11, ergosterol biosynthesis, sterol 14-demethylase activity, endoplasmic reticulum |
| 42. |
YIL160C |
34 |
-140.3 |
acetyl-CoA C-acyltransferase, peroxisomal, POT1, fatty acid beta-oxidation, acetyl-CoA C-acyltransferase activity, peroxisomal matrix |
| 43. |
YDR062W |
246 |
-136.2 |
serine C-palmitoyltransferase subunit, LCB2, sphingolipid biosynthesis, serine C-palmitoyltransferase activity, membrane fraction |
| 44. |
YLR100W |
266 |
-133.2 |
3-keto sterol reductase, ERG27, ergosterol biosynthesis, 3-keto sterol reductase activity, endoplasmic reticulum |
| 45. |
YOR109W |
280 |
-131.4 |
phosphatidylinositol phosphate phosphatase, INP53, cell wall organization and biogenesis, inositol-polyphosphate 5-phosphatase activity, membrane fraction |
| 46. |
YGR175C |
335 |
-128.4 |
squalene monooxygenase, ERG1, ergosterol biosynthesis, drug binding, endoplasmic reticulum |
| 47. |
YOL151W |
385 |
-127.5 |
methylglyoxal reductase (NADPH-dependent) , GRE2, response to stress, oxidoreductase activity, cytoplasm |
| 48. |
YGR019W |
225 |
-126.8 |
4-aminobutyrate aminotransferase (GABA transaminase), UGA1, nitrogen utilization, 4-aminobutyrate transaminase activity, intracellular |
| 49. |
YPL117C |
482 |
-125.4 |
isopentenyl-diphosphate delta-isomerase, IDI1, ergosterol biosynthesis, isopentenyl-diphosphate delta-isomerase activity, cytosol |
| 50. |
YMR008C |
131 |
-122.1 |
phospholipase B (lysophospholipase), PLB1, glycerophospholipid metabolism, lysophospholipase activity, cell wall (sensu Fungi) |
| 51. |
YNL048W |
72 |
-122.1 |
required for asparagine-linked glycosylation, ALG11, protein amino acid glycosylation, alpha-1, 2-mannosyltransferase activity, endoplasmic reticulum |
| 52. |
YGL055W |
341 |
-118.8 |
stearoyl-CoA desaturase, OLE1, mitochondrion inheritance, stearoyl-CoA 9-desaturase activity, endoplasmic reticulum membrane |
| 53. |
YBR109C |
587 |
-118.6 |
calmodulin, CMD1, cytoskeleton organization and biogenesis, calcium ion binding, cytoplasm |
| 54. |
YGL001C |
198 |
-102.2 |
C-3 sterol dehydrogenase (C-4 decarboxylase), ERG26, ergosterol biosynthesis, C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity, endoplasmic reticulum |
| 55. |
YKL140W |
101 |
-101.6 |
triacylglycerol lipase, TGL1, lipid metabolism, lipase activity, lipid particle |
| 56. |
YMR246W |
477 |
-101 |
long-chain-fatty-acid--CoA ligase, FAA4, lipid metabolism, long-chain-fatty-acid-CoA ligase activity, cytoplasm |
| 57. |
YER093C |
24 |
-99.6 |
lipid biosynthesis, binding of TOR, TSC11, sphingolipid biosynthesis, protein binding, cellular_component unknown |
| 58. |
YPR113W |
214 |
-99 |
CDP diacylglycerol--inositol 3-phosphatidyltransferase, PIS1, phosphatidylinositol biosynthesis, CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity, endoplasmic reticulum |
| 59. |
YBL011W |
61 |
-98 |
glycerol 3-phosphate/dihydroxyacetone phosphate dual substrate acyltransferase, SCT1, phospholipid biosynthesis, glycerol-3-phosphate O-acyltransferase activity, endoplasmic reticulum |
| 60. |
YHR188C |
61 |
-93.8 |
similarity to hypothetical C. elegans proteins F17c11.7, GPI16, attachment of GPI anchor to protein, GPI-anchor transamidase activity, integral to endoplasmic reticulum membrane |
| 61. |
YOL018C |
40 |
-93 |
member of the syntaxin family of t-SNAREs, TLG2, vesicle fusion, v-SNARE activity, Golgi trans face |
| 62. |
YPL006W |
84 |
-89 |
similarity to human PTC protein involved in nevoid basal cell carcinoma syndrome, NCR1, sphingolipid metabolism, sphingolipid transporter activity, vacuolar membrane (sensu Fungi) |
| 63. |
YNL128W |
15 |
-85.4 |
protein involved in developmental trafficking phosphatidylinositol pathway, TEP1, spore wall assembly (sensu Fungi), inositol or phosphatidylinositol phosphatase activity, cellular_component unknown |
| 64. |
YBR042C |
46 |
-81.9 |
weak similarity to 1-acyl-sn-glycerol-3-phosphate acyltransferase from Brassica napus, phospholipid biosynthesis, acyltransferase activity, lipid particle |
| 65. |
YGL065C |
101 |
-81.7 |
mannosyltransferase, ALG2, oligosaccharide-lipid intermediate assembly, glycolipid mannosyltransferase activity, endoplasmic reticulum |
| 66. |
YHR001W |
154 |
-81.1 |
similarity to Kes1p, OSH7, steroid biosynthesis, oxysterol binding, cellular_component unknown |
| 67. |
YLR450W |
203 |
-80.9 |
3-hydroxy-3-methylglutaryl-coenzyme A reductase 2, HMG2, ergosterol biosynthesis, hydroxymethylglutaryl-CoA reductase (NADPH) activity, endoplasmic reticulum membrane |
| 68. |
YMR006C |
51 |
-80.5 |
strong similarity to Plb1p, YOL011w and P.notatum lysophospholipase, PLB2, glycerophospholipid metabolism, lysophospholipase activity, cell wall (sensu Fungi) |
| 69. |
YNL045W |
258 |
-79.4 |
protein hydralyse leukotriene like substrates, lipid metabolism, aminopeptidase activity, cytoplasm |
| 70. |
YBR160W |
260 |
-78.9 |
cyclin-dependent protein kinase, CDC28, protein amino acid phosphorylation, cyclin-dependent protein kinase activity, cytoplasm |
| 71. |
YGR060W |
105 |
-78.5 |
C-4 sterol methyl oxidase, ERG25, ergosterol biosynthesis, C-4 methyl sterol oxidase activity, plasma membrane |
| 72. |
YMR015C |
138 |
-77.4 |
C-22 sterol desaturase, ERG5, ergosterol biosynthesis, C-22 sterol desaturase activity, endoplasmic reticulum |
| 73. |
YNL231C |
240 |
-77.3 |
protein involved in lipid biosynthesis and multidrug resistance, PDR16, response to drug, phosphatidylinositol transporter activity, cytoplasm |
| 74. |
YDL052C |
201 |
-75.9 |
fatty acyltransferase, SLC1, sphingolipid biosynthesis, 1-acylglycerol-3-phosphate O-acyltransferase activity, lipid particle |
| 75. |
YKL126W |
243 |
-74.6 |
ser/thr-specific protein kinase, YPK1, protein amino acid phosphorylation, protein serine/threonine kinase activity, plasma membrane |
| 76. |
YBR041W |
135 |
-73.8 |
very long-chain fatty acyl-CoA synthetase , FAT1, lipid transport, long-chain-fatty-acid-CoA ligase activity, plasma membrane |
| 77. |
YPR128C |
78 |
-73.3 |
Peroxisomal transporter of adenine nucleotides (ATP, AMP), ANT1, peroxisome organization and biogenesis, adenine nucleotide transporter activity, cytoplasm |
| 78. |
YML059C |
101 |
-71.5 |
similarity to C.elegans ZK370.4 protein, phosphatidylcholine metabolism, lysophospholipase activity, endoplasmic reticulum |
| 79. |
YLR372W |
412 |
-71.4 |
sterol isomerase, fatty acid elongase, SUR4, sphingolipid biosynthesis, fatty acid elongase activity, endoplasmic reticulum |
| 80. |
YBR006W |
149 |
-69.3 |
succinate semialdehyde dehydrogenase, UGA2, response to oxidative stress, succinate-semialdehyde dehydrogenase [NAD(P)+] activity, cytoplasm |
| 81. |
YML075C |
279 |
-68.7 |
3-hydroxy-3-methylglutaryl-coenzyme A reductase 1, HMG1, ergosterol biosynthesis, hydroxymethylglutaryl-CoA reductase (NADPH) activity, endoplasmic reticulum membrane |
| 82. |
YNR008W |
84 |
-68.3 |
a lecithin cholesterol acyltransferase-like gene, mediates diacylglycerol esterification, LRO1, triacylglycerol biosynthesis, phospholipid:diacylglycerol acyltransferase activity, endoplasmic reticulum |
| 83. |
YGL012W |
112 |
-67.7 |
sterol C-24 reductase, ERG4, ergosterol biosynthesis, delta24(24-1) sterol reductase activity, endoplasmic reticulum |
| 84. |
YBR029C |
206 |
-65.4 |
CDP-diacylglycerol synthase, CDS1, phosphatidylglycerol biosynthesis, phosphatidate cytidylyltransferase activity, mitochondrion |
| 85. |
YNL280C |
42 |
-64.9 |
C-14 sterol reductase, ERG24, ergosterol biosynthesis, C-14 sterol reductase activity, endoplasmic reticulum |
| 86. |
YGR143W |
54 |
-64.5 |
glucan synthase subunit, SKN1, cell wall organization and biogenesis, glucosidase activity, integral to membrane |
| 87. |
YMR202W |
212 |
-64.3 |
C-8 sterol isomerase, ERG2, ergosterol biosynthesis, C-8 sterol isomerase activity, endoplasmic reticulum |
| 88. |
YOR221C |
64 |
-63.7 |
malonyl-CoA:ACP transferase, MCT1, aerobic respiration, [acyl-carrier protein] S-malonyltransferase activity, mitochondrion |
| 89. |
YLR056W |
124 |
-60.6 |
C-5 sterol desaturase, ERG3, ergosterol biosynthesis, C-5 sterol desaturase activity, endoplasmic reticulum |
| 90. |
YCR034W |
128 |
-60.1 |
fatty acid elongase required for sphingolipid formation, FEN1, vesicle-mediated transport, fatty acid elongase activity, endoplasmic reticulum |
| 91. |
YBR265W |
64 |
-59.9 |
3-ketosphinganine reductase, TSC10, sphingolipid biosynthesis, oxidoreductase activity, acting on NADH or NADPH, cytoplasm |
| 92. |
YDL015C |
140 |
-59.9 |
required for elongation of the very long chain fatty acid (VLCFA) moiety of sphingolipids, TSC13, very-long-chain fatty acid metabolism, oxidoreductase activity, endoplasmic reticulum membrane |
| 93. |
YJR019C |
36 |
-59.6 |
thioesterase, peroxisomal, TES1, fatty acid oxidation, acyl-CoA thioesterase activity, peroxisome |
| 94. |
YLR386W |
119 |
-59.5 |
similarity to hypothetical S. pombe protein, VAC14, vacuole inheritance, enzyme activator activity, vacuole |
| 95. |
YLR380W |
224 |
-59.3 |
phosphatidylinositol transfer protein, CSR1, cell wall organization and biogenesis, phosphatidylinositol transporter activity, cytoplasm |
| 96. |
YGR037C |
451 |
-59.2 |
acyl-coenzyme-A-binding protein (diazepam binding inhibitor), ACB1, fatty acid metabolism, long-chain fatty acid transporter activity, cytoplasm |
| 97. |
YER026C |
177 |
-57.3 |
CDP-diacylglycerol serine O-phosphatidyltransferase, CHO1, phosphatidylserine biosynthesis, CDP-diacylglycerol-serine O-phosphatidyltransferase activity, endoplasmic reticulum |
| 98. |
YPL206C |
87 |
-57 |
weak similarity to glycerophosphoryl diester phosphodiesterases, biological_process unknown, molecular_function unknown, cytoplasm |
| 99. |
YKR089C |
82 |
-56.7 |
strong similarity to YOR081c, STC1, biological_process unknown, molecular_function unknown, lipid particle |
| 100. |
YBR026C |
234 |
-54.8 |
mitochondrial respiratory function protein, ETR1, aerobic respiration, enoyl-[acyl-carrier protein] reductase activity, mitochondrion |
| 101. |
YNL202W |
55 |
-52.8 |
peroxisomal 2, 4-dienoyl-CoA reductase, SPS19, sporulation (sensu Fungi), 2, 4-dienoyl-CoA reductase (NADPH) activity, peroxisomal matrix |
| 102. |
YMR272C |
276 |
-52.1 |
required for hydroxylation of ceramide, SCS7, fatty acid metabolism, oxidoreductase activity, endoplasmic reticulum |
| 103. |
YOL147C |
79 |
-51.9 |
peroxisomal membrane protein - peroxin, PEX11, peroxisome organization and biogenesis, molecular_function unknown, peroxisomal membrane |
| 104. |
YJL097W |
29 |
-51.7 |
similarity to hypothetical C. elegans protein T15B7.2, biological_process unknown, molecular_function unknown, endoplasmic reticulum |
| 105. |
YBR110W |
64 |
-50.8 |
beta-mannosyltransferase, ALG1, N-linked glycosylation, beta-1, 4-mannosyltransferase activity, integral to membrane |
| 106. |
YCR017C |
92 |
-50.2 |
putative sensor/transporter protein, CWH43, cell wall organization and biogenesis, molecular_function unknown, bud neck |
| 107. |
YER019W |
77 |
-48.9 |
weak similarity to human and mouse neutral sphingomyelinase, ISC1, response to salt stress, phospholipase C activity, cellular_component unknown |
| 108. |
YKL008C |
94 |
-48.5 |
protein required with Lag1p for ER-to-Golgi transport of GPI-anchored proteins, LAC1, ceramide biosynthesis, sphingosine N-acyltransferase activity, endoplasmic reticulum |
| 109. |
YDR284C |
85 |
-48 |
diacylglycerol pyrophosphate phosphatase, DPP1, signal transduction, diacylglycerol pyrophosphate phosphatase activity, vacuolar membrane (sensu Fungi) |
| 110. |
YNL009W |
535 |
-47.5 |
isocitrate dehydrogenase, NADP-dependent, IDP3, fatty acid beta-oxidation, isocitrate dehydrogenase (NADP+) activity, cytoplasm |
| 111. |
YNL169C |
96 |
-46.9 |
phosphatidylserine decarboxylase 1, PSD1, phosphatidylcholine biosynthesis, phosphatidylserine decarboxylase activity, mitochondrion |
| 112. |
YPL110C |
81 |
-46.5 |
similarity to C.elegans hypothetical protein, weak similarity to Pho81p, biological_process unknown, molecular_function unknown, cytoplasm |
| 113. |
YCL052C |
22 |
-45 |
required for post-translational processing of the protease B precursor Prb1p, PBN1, protein processing, molecular_function unknown, endoplasmic reticulum |
| 114. |
YPR173C |
108 |
-43.5 |
vacuolar sorting protein, VPS4, late endosome to vacuole transport, ATPase activity, cytoplasm |
| 115. |
YGL225W |
139 |
-40.3 |
Nucleotide-sugar permease of the Golgi - promotes transport of GDP-mannose, VRG4, N-linked glycosylation, nucleotide-sugar transporter activity, Golgi apparatus |
| 116. |
YER044C |
135 |
-39.3 |
involved in synthesis of ergosterol, ERG28, ergosterol biosynthesis, molecular_function unknown, endoplasmic reticulum membrane |
| 117. |
YHR072W |
94 |
-39.1 |
lanosterol synthase, ERG7, ergosterol biosynthesis, lanosterol synthase activity, plasma membrane |
| 118. |
YNL264C |
72 |
-38.9 |
involved in regulating phosphatidylserine metabolism, PDR17, response to drug, phosphatidylinositol transporter activity, cytoplasm |
| 119. |
YGR202C |
56 |
-38.9 |
cholinephosphate cytidylyltransferase, PCT1, phosphatidylcholine biosynthesis, choline-phosphate cytidylyltransferase activity, nucleus |
| 120. |
YMR207C |
490 |
-38.5 |
strong similarity to acetyl-CoA carboxylase, HFA1, fatty acid biosynthesis, acetyl-CoA carboxylase activity, mitochondrion |
| 121. |
YNL111C |
35 |
-38.2 |
cytochrome b5, CYB5, sterol biosynthesis, electron transporter activity, endoplasmic reticulum membrane |
| 122. |
YKR031C |
51 |
-37.7 |
phospholipase D, SPO14, sporulation (sensu Fungi), phospholipase D activity, endosome |
| 123. |
YOR171C |
129 |
-36.4 |
sphingolipid long chain base kinase, LCB4, sphingolipid metabolism, D-erythro-sphingosine kinase activity, endoplasmic reticulum |
| 124. |
YMR165C |
44 |
-36.3 |
involved in plasmid maintenance, respiration and cell proliferation, SMP2, aerobic respiration, molecular_function unknown, cytoplasm |
| 125. |
YKR003W |
176 |
-36.1 |
similarity to Kes1p, Hes1p and Osh1p, OSH6, steroid biosynthesis, oxysterol binding, cellular_component unknown |
| 126. |
YMR313C |
31 |
-34.8 |
similarity to YKR089c and YOR081c, TGL3, lipid metabolism, triacylglycerol lipase activity, lipid particle |
| 127. |
YGL084C |
86 |
-34.6 |
similarity to Gup2p - putative glycerol transporter, GUP1, glycerol catabolism, glycerol transporter activity, membrane |
| 128. |
YLR088W |
61 |
-32.7 |
required for attachment of GPI anchor onto proteins, GAA1, attachment of GPI anchor to protein, GPI-anchor transamidase activity, integral to endoplasmic reticulum membrane |
| 129. |
YHR133C |
69 |
-32.5 |
similarity to hypothetical protein YNL156c, NSG1, biological_process unknown, molecular_function unknown, cellular_component unknown |
| 130. |
YPL170W |
85 |
-31 |
similarity to C.elegans LIM homeobox protein, DAP1, sterol metabolism, molecular_function unknown, membrane |
| 131. |
YJL196C |
54 |
-30.2 |
fatty acid elongation protein, ELO1, fatty acid elongation, unsaturated fatty acid, fatty acid elongase activity, membrane |
| 132. |
YMR220W |
176 |
-29.6 |
phosphomevalonate kinase, ERG8, ergosterol biosynthesis, phosphomevalonate kinase activity, cytosol |
| 133. |
YGL126W |
33 |
-28.6 |
inositol phospholipid synthesis protein, SCS3, phospholipid metabolism, molecular_function unknown, endoplasmic reticulum |
| 134. |
YOR311C |
56 |
-27.4 |
similarity to hypothetical S. pombe protein, HSD1, biological_process unknown, molecular_function unknown, integral to membrane |
| 135. |
YLR240W |
33 |
-26.9 |
phosphatidylinositol 3-kinase, VPS34, protein amino acid phosphorylation, protein kinase activity, membrane fraction |
| 136. |
YMR208W |
233 |
-26.6 |
mevalonate kinase, ERG12, ergosterol biosynthesis, mevalonate kinase activity, cytosol |
| 137. |
YLR133W |
124 |
-26.1 |
choline kinase, CKI1, phosphatidylcholine biosynthesis, choline kinase activity, cytosol |
| 138. |
YIL002C |
33 |
-26.1 |
phosphatidylinositol phosphate 5-phosphatase, INP51, cell wall organization and biogenesis, inositol-polyphosphate 5-phosphatase activity, membrane fraction |
| 139. |
YPL069C |
38 |
-25.8 |
geranylgeranyl diphosphate synthase, BTS1, terpenoid biosynthesis, farnesyltranstransferase activity, mitochondrion |
| 140. |
YBR183W |
41 |
-25.4 |
Alkaline Ceramidase, YPC1, ceramide metabolism, ceramidase activity, endoplasmic reticulum |
| 141. |
YHL003C |
93 |
-25.3 |
longevity-assurance protein, LAG1, replicative cell aging, sphingosine N-acyltransferase activity, endoplasmic reticulum |
| 142. |
YLR260W |
108 |
-25.1 |
sphingolipid long chain base kinase, LCB5, response to heat, D-erythro-sphingosine kinase activity, membrane fraction |
| 143. |
YJL062W |
39 |
-24.9 |
required for addition of a side chain to the glycosylphospatidylinositol (GPI) core structure, LAS21, GPI anchor biosynthesis, transferase activity, integral to plasma membrane |
| 144. |
YHL020C |
27 |
-24.9 |
negative regulator of phospholipid biosynthesis pathway, OPI1, positive regulation of transcription from Pol II promoter, transcription corepressor activity, nucleus |
| 145. |
YOR245C |
39 |
-24.7 |
similarity to hypothetical C. elegans proteins, DGA1, triacylglycerol biosynthesis, diacylglycerol O-acyltransferase activity, lipid particle |
| 146. |
YNL156C |
26 |
-23.7 |
similarity to YHR133c, NSG2, biological_process unknown, molecular_function unknown, endoplasmic reticulum |
| 147. |
YDR208W |
69 |
-23.5 |
phosphatidylinositol-4-phosphate 5-kinase, MSS4, actin cytoskeleton organization and biogenesis, 1-phosphatidylinositol-4-phosphate 5-kinase activity, plasma membrane |
| 148. |
YLR020C |
42 |
-22.8 |
similarity to triacylglycerol lipase, cell wall mannoprotein biosynthesis, molecular_function unknown, cellular_component unknown |
| 149. |
YLL031C |
81 |
-22.7 |
protein involved in glycosylphosphatidylinositol biosynthesis, GPI13, GPI anchor biosynthesis, phosphoethanolamine N-methyltransferase activity, endoplasmic reticulum |
| 150. |
YGL142C |
6 |
-22.3 |
required for Glycosyl Phosphatdyl Inositol synthesis, GPI10, GPI anchor biosynthesis, molecular_function unknown, integral to membrane |
| 151. |
YBR058C-A |
41 |
-22 |
required for optimal serine palmitoyltransferase activity, TSC3, sphingolipid biosynthesis, enzyme activator activity, membrane fraction |
| 152. |
YIL009W |
175 |
-21.7 |
acyl CoA synthase, FAA3, lipid metabolism, long-chain-fatty-acid-CoA ligase activity, cellular_component unknown |
| 153. |
YJL134W |
18 |
-21.6 |
sphingoid base-phosphate phosphatase, LCB3, sphingolipid biosynthesis, sphingosine-1-phosphate phosphatase activity, endoplasmic reticulum |
| 154. |
YIR033W |
24 |
-21.6 |
may be involved in the remodeling chromatin structure, MGA2, positive regulation of transcription from Pol II promoter, transcriptional activator activity, endoplasmic reticulum membrane |
| 155. |
YMR281W |
5 |
-20.5 |
N-acetylglucosaminyl phosphatidylinositol deacetylase, GPI12, GPI anchor biosynthesis, N-acetylglucosaminylphosphatidylinositol deacetylase activity, endoplasmic reticulum membrane |
| 156. |
YEL050C |
16 |
-19.7 |
mitochondrial ribosomal protein, large subunit, RML2, protein biosynthesis, structural constituent of ribosome, mitochondrial large ribosomal subunit |
| 157. |
YKL020C |
43 |
-19 |
dosage-dependent suppressor of Ty-induced promotor mutations, SPT23, positive regulation of transcription from Pol II promoter, transcriptional activator activity, endoplasmic reticulum membrane |
| 158. |
YMR298W |
42 |
-18.7 |
hypothetical protein, biological_process unknown, molecular_function unknown, endoplasmic reticulum |
| 159. |
YFL031W |
2 |
-18.7 |
transcription factor, HAC1, regulation of transcription from Pol II promoter, specific RNA polymerase II transcription factor activity, nucleus |
| 160. |
YNL158W |
5 |
-18.2 |
hypothetical protein, biological_process unknown, molecular_function unknown, nuclear membrane |
| 161. |
YNL267W |
62 |
-18 |
phosphatidylinositol 4-kinase, PIK1, cytokinesis, 1-phosphatidylinositol 4-kinase activity, nucleus |
| 162. |
YNL130C |
65 |
-18 |
diacylglycerol cholinephosphotransferase, CPT1, phosphatidylcholine biosynthesis, diacylglycerol cholinephosphotransferase activity, endoplasmic reticulum |
| 163. |
YDR096W |
53 |
-17.9 |
DNA damage-responsive repressor of PHR1, GIS1, phospholipid metabolism, transcription factor activity, nucleus |
| 164. |
YGR177C |
20 |
-17.8 |
alcohol O-acetyltransferase, ATF2, steroid metabolism, alcohol O-acetyltransferase activity, cytoplasm |
| 165. |
YNR019W |
35 |
-17.4 |
acyl-CoA sterol acyltransferase, ARE2, sterol metabolism, sterol O-acyltransferase activity, endoplasmic reticulum |
| 166. |
YBR002C |
33 |
-17.3 |
cis-prenyltransferase, a key enzyme in dolichol synthesis, RER2, protein amino acid glycosylation, prenyltransferase activity, endoplasmic reticulum |
| 167. |
YCR044C |
22 |
-16.7 |
involved in manganese homeostasis, PER1, response to unfolded protein, molecular_function unknown, vacuolar membrane (sensu Fungi) |
| 168. |
YPL057C |
12 |
-16.7 |
required for mannosylation of sphingolipids, SUR1, sphingolipid biosynthesis, mannosyltransferase activity, intracellular |
| 169. |
YAL051W |
28 |
-16.6 |
peroxisome proliferating transcription factor, OAF1, peroxisome organization and biogenesis, DNA binding, nucleus |
| 170. |
YPL087W |
48 |
-16.4 |
alkaline dihydroceramidase, YDC1, response to heat, ceramidase activity, endoplasmic reticulum |
| 171. |
YFR019W |
55 |
-16.2 |
phosphatidylinositol 3-phosphate 5-kinase, FAB1, response to stress, 1-phosphatidylinositol-3-phosphate 5-kinase activity, vacuolar membrane |
| 172. |
YER061C |
28 |
-15.7 |
beta-keto-acyl-ACP synthase, mitochondrial, CEM1, hexadecanal biosynthesis, 3-oxoacyl-[acyl-carrier protein] synthase activity, mitochondrion |
| 173. |
YGR007W |
47 |
-15.4 |
choline phosphate cytidylyltransferase, MUQ1, phosphatidylethanolamine biosynthesis, ethanolamine-phosphate cytidylyltransferase activity, cytoplasm |
| 174. |
YJL091C |
25 |
-15.4 |
weak similarity to human G protein-coupled receptor, GWT1, GPI anchor biosynthesis, molecular_function unknown, membrane |
| 175. |
YBR036C |
61 |
-15.4 |
calcium dependent regulatory protein, CSG2, calcium ion homeostasis, enzyme regulator activity, integral to endoplasmic reticulum membrane |
| 176. |
YOR363C |
26 |
-15.4 |
peroxisome proliferating transcription factor, PIP2, peroxisome organization and biogenesis, DNA binding, nucleus |
| 177. |
YOR067C |
69 |
-15.3 |
glucosyltransferase, ALG8, dolichol-linked oligosaccharide biosynthesis, oligosaccharyl transferase activity, endoplasmic reticulum membrane |
| 178. |
YNL325C |
104 |
-15 |
weak similarity to inositol phosphatase, FIG4, cellular morphogenesis during conjugation with cellular fusion, polyphosphoinositide phosphatase activity, extrinsic to membrane |
| 179. |
YOL011W |
23 |
-14.8 |
phospholipase B (lysophospholipase), PLB3, phosphoinositide metabolism, lysophospholipase activity, plasma membrane |
| 180. |
YDR147W |
9 |
-14.6 |
ethanolamine kinase, EKI1, phosphatidylethanolamine biosynthesis, choline kinase activity, cytoplasm |
| 181. |
YKL004W |
14 |
-14.1 |
aureobasidin-resistance protein, AUR1, sphingolipid metabolism, inositol phosphoceramide synthase activity, Golgi apparatus |
| 182. |
YDR297W |
23 |
-14 |
required for the hydroxylation of C-4 of the sphingoid moiety of ceramide, SUR2, sphingolipid biosynthesis, sphingosine hydroxylase activity, endoplasmic reticulum |
| 183. |
YLR189C |
28 |
-13.8 |
sterol glucosyltransferase (UDP-glucose:sterol glucosyltransferase), ATG26, sterol metabolism, sterol 3-beta-glucosyltransferase activity, cytoplasm |
| 184. |
YPL103C |
21 |
-13.7 |
similarity to hypothetical M. tuberculosis protein, FMP30, biological_process unknown, molecular_function unknown, cellular_component unknown |
| 185. |
YLR284C |
35 |
-13.5 |
delta3-cis-delta2-trans-enoyl-CoA isomerase, ECI1, fatty acid beta-oxidation, dodecenoyl-CoA delta-isomerase activity, peroxisome |
| 186. |
YGR170W |
134 |
-12.8 |
phosphatidylserine decarboxylase 2, PSD2, phosphatidylcholine biosynthesis, phosphatidylserine decarboxylase activity, vacuolar membrane (sensu Fungi) |
| 187. |
YLR459W |
20 |
-12.6 |
cell division control protein, GAB1, attachment of GPI anchor to protein, GPI-anchor transamidase activity, endoplasmic reticulum membrane |
| 188. |
YJL100W |
8 |
-12 |
similarity to hypothetical C. elegans protein C56A3.8, LSB6, actin filament organization, 1-phosphatidylinositol 4-kinase activity, cytoplasm |
| 189. |
YJR013W |
15 |
-11.9 |
similarity to C.elegans B0491.1 protein, PMH1, GPI anchor biosynthesis, mannosyltransferase activity, endoplasmic reticulum membrane |
| 190. |
YLR228C |
26 |
-11.9 |
strong similarity to YDR213w, weak similarity to Lys14p, ECM22, sterol biosynthesis, RNA polymerase II transcription factor activity, nucleus |
| 191. |
YBL082C |
17 |
-11.7 |
mannosyltransferase, RHK1, protein amino acid glycosylation, alpha-1, 3-mannosyltransferase activity, endoplasmic reticulum |
| 192. |
YDR302W |
4 |
-11.5 |
GPI11 - protein involved in glycosylphosphatidylinositol (GPI) biosynthesis, GPI11, GPI anchor biosynthesis, phosphoethanolamine N-methyltransferase activity, endoplasmic reticulum |
| 193. |
YOR377W |
7 |
-11.3 |
alcohol acetyltransferase, ATF1, fatty acid metabolism, alcohol O-acetyltransferase activity, lipid particle |
| 194. |
YOR081C |
29 |
-11 |
strong similarity to YKR089c, STC2, biological_process unknown, molecular_function unknown, lipid particle |
| 195. |
YGR263C |
18 |
-10.7 |
weak similarity to E.coli lipase like enzyme, biological_process unknown, molecular_function unknown, endoplasmic reticulum |
| 196. |
YPL268W |
28 |
-10.3 |
1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase, PLC1, pseudohyphal growth, phosphoinositide phospholipase C activity, nucleus |
| 197. |
YGL144C |
12 |
-9.9 |
strong similarity to hypothetical protein YDL109c, ROG1, lipid metabolism, lipase activity, cellular_component unknown |
| 198. |
YOR100C |
15 |
-9.8 |
Mitochondrial carnitine carrier - member of the mitochondrial carrier (MCF) family, CRC1, fatty acid metabolism, carnitine:acyl carnitine carrier activity, mitochondrion |
| 199. |
YDR173C |
32 |
-9.6 |
arginine metabolism transcription factor, ARG82, arginine metabolism, inositol or phosphatidylinositol kinase activity, nucleus |
| 200. |
YPR140W |
13 |
-9.3 |
similarity to human BTHS gene involved in Barth syndrome, TAZ1, phospholipid biosynthesis, acyltransferase activity, mitochondrion |
| 201. |
YNL054W |
15 |
-9.2 |
vacuolar protein, VAC7, vacuole inheritance, enzyme regulator activity, cytoplasm |
| 202. |
YPL120W |
13 |
-9.1 |
involved in vacuolare protein sorting and autophagy, VPS30, protein-vacuolar targeting, molecular_function unknown, membrane fraction |
| 203. |
YHR123W |
15 |
-9 |
sn-1, 2-diacylglycerol ethanolamine- and cholinephosphotransferase, EPT1, phosphatidylethanolamine biosynthesis, ethanolaminephosphotransferase activity, endoplasmic reticulum |
| 204. |
YOR025W |
24 |
-8.8 |
silencing protein, HST3, chromatin silencing at telomere, DNA binding, nucleus |
| 205. |
YDR331W |
33 |
-8.2 |
essential for GPI anchor attachment, GPI8, attachment of GPI anchor to protein, GPI-anchor transamidase activity, integral to endoplasmic reticulum membrane |
| 206. |
YCL026C-A |
14 |
-7.6 |
involved in fatty acid regulation, FRM2, negative regulation of fatty acid metabolism, molecular_function unknown, cytoplasm |
| 207. |
YDR191W |
5 |
-7.6 |
member of the Sir2p family of putative NAD-dependent histone deacetylases, HST4, chromatin silencing at telomere, DNA binding, cytoplasm |
| 208. |
YJR110W |
24 |
-7.6 |
similarity to human myotubularin, YMR1, biological_process unknown, phosphoric monoester hydrolase activity, cytoplasm |
| 209. |
YDR492W |
3 |
-7.5 |
Implicated in Zinc Homeostasis, membran protein, IZH1, lipid metabolism, metal ion binding, endoplasmic reticulum |
| 210. |
YAL009W |
2 |
-7.5 |
meiotic protein, SPO7, meiosis, molecular_function unknown, integral to membrane |
| 211. |
YLR099C |
6 |
-7.4 |
similarity to YDR125c, ICT1, biological_process unknown, molecular_function unknown, cellular_component unknown |
| 212. |
YDR213W |
24 |
-6.8 |
regulatory protein involved in control of sterol uptake, UPC2, sterol biosynthesis, RNA polymerase II transcription factor activity, cytoplasm |
| 213. |
YOR002W |
12 |
-6.6 |
glucosyltransferase, ALG6, protein amino acid glycosylation, transferase activity, transferring hexosyl groups, endoplasmic reticulum |
| 214. |
YBL091C-A |
6 |
-6.5 |
Suppressor of Choline Sensitivity, homologous to SCS2, SCS22, biological_process unknown, molecular_function unknown, cellular_component unknown |
| 215. |
YCR048W |
21 |
-6.1 |
acyl-CoA sterol acyltransferase, ARE1, sterol metabolism, sterol O-acyltransferase activity, endoplasmic reticulum |
| 216. |
YKL055C |
9 |
-6 |
putative 3-oxoacyl-(acyl carrier protein) reductase, OAR1, aerobic respiration, 3-oxoacyl-[acyl-carrier protein] reductase activity, mitochondrion |
| 217. |
YKR064W |
24 |
-6 |
weak similarity to transcription factors, biological_process unknown, molecular_function unknown, cytoplasm |
| 218. |
YPL095C |
29 |
-6 |
strong similarity to YBR177c, biological_process unknown, molecular_function unknown, cellular_component unknown |
| 219. |
YLL012W |
20 |
-5.9 |
similarity to triacylglycerol lipases, biological_process unknown, molecular_function unknown, lipid particle |
| 220. |
YPL175W |
6 |
-5.6 |
N-acetylglucosaminyltransferase, SPT14, GPI anchor biosynthesis, transferase activity, transferring hexosyl groups, endoplasmic reticulum |
| 221. |
YDR058C |
8 |
-5.4 |
triacylglycerol lipase, TGL2, lipid metabolism, triacylglycerol lipase activity, cellular_component unknown |
| 222. |
YBR004C |
7 |
-5.3 |
similarity to S.pombe hypothetical protein SPAC18B11.05, FMP44, biological_process unknown, molecular_function unknown, cellular_component unknown |
| 223. |
YCL004W |
16 |
-5.3 |
phosphatidylglycerophosphate synthase, PGS1, phospholipid biosynthesis, CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity, mitochondrion |
| 224. |
YFL025C |
17 |
-5.3 |
negative regulator of COPII vesicle formation, BST1, ER-associated protein catabolism, carboxylic ester hydrolase activity, endoplasmic reticulum |
| 225. |
YHR004C |
16 |
-5.3 |
required for nuclear morphology, NEM1, sporulation (sensu Fungi), molecular_function unknown, integral to membrane |
| 226. |
YDR123C |
6 |
-4.9 |
basic helix-loop-helix (BHLH) transcription factor, INO2, positive regulation of transcription from Pol II promoter, specific RNA polymerase II transcription factor activity, nucleus |
| 227. |
YDL142C |
3 |
-4.2 |
cardiolipin synthase, CRD1, lipid biosynthesis, cardiolipin synthase activity, mitochondrial membrane |
| 228. |
YBR132C |
14 |
-3.3 |
Carnitine permease, AGP2, response to osmotic stress, amino acid transporter activity, endoplasmic reticulum membrane |
| 229. |
YOR298W |
13 |
-3.2 |
required for meiosis, phospholipid biosynthesis, acyltransferase activity, cellular_component unknown |
| 230. |
YOR180C |
5 |
-3.1 |
Enoyl-CoA Hydratase, peroxisomal, DCI1, fatty acid beta-oxidation, dodecenoyl-CoA delta-isomerase activity, peroxisomal matrix |
| 231. |
YDR503C |
9 |
-2.9 |
lipid phosphate phosphatase, LPP1, phospholipid metabolism, phosphatidate phosphatase activity, membrane |
| 232. |
YHR067W |
2 |
-2.7 |
weak similarity to PIR:T39292 hypothetical protein SPBC1105.15c S. pombe, RMD12, biological_process unknown, molecular_function unknown, mitochondrion |
| 233. |
YOL065C |
7 |
-2.7 |
inositol polyphosphate 5-phosphatase, INP54, exocytosis, inositol-polyphosphate 5-phosphatase activity, endoplasmic reticulum |
| 234. |
YDR018C |
5 |
-2.7 |
strong similarity to hypothetical protein YBR042c, phospholipid biosynthesis, acyltransferase activity, cellular_component unknown |
| 235. |
YGR216C |
4 |
-2.5 |
required for N-acetylglucosaminyl phosphatidylinositol synthesis, GPI1, GPI anchor biosynthesis, molecular_function unknown, membrane |
| 236. |
YMR210W |
13 |
-2.4 |
similarity to P.glauca late embryogenesis abundant protein and YBR177c and YPL095c, biological_process unknown, molecular_function unknown, cellular_component unknown |
| 237. |
YDL170W |
8 |
-2.4 |
transcriptional activator for GABA catabolic genes, UGA3, regulation of transcription from Pol II promoter, specific RNA polymerase II transcription factor activity, nucleus |
| 238. |
YDL109C |
12 |
-2.3 |
strong similarity to hypothetical protein YGL144c, lipid metabolism, lipase activity, cellular_component unknown |
| 239. |
YKR053C |
10 |
-2.1 |
dihydrosphingosine-1-phosphate phosphatase, YSR3, sphingolipid biosynthesis, sphingosine-1-phosphate phosphatase activity, endoplasmic reticulum |
| 240. |
YLR242C |
1 |
-2 |
involved in sterol uptake and distribution into the plasma membrane, ARV1, sterol transport, molecular_function unknown, endoplasmic reticulum |
| 241. |
YOL101C |
3 |
-1.8 |
Implicated in Zinc Homeostasis, membran protein, IZH4, lipid metabolism, metal ion binding, membrane |
| 242. |
YOR149C |
3 |
-1.7 |
protein kinase C pathway protein, SMP3, GPI anchor biosynthesis, alpha-1, 2-mannosyltransferase activity, endoplasmic reticulum |
| 243. |
YBR161W |
7 |
-1.7 |
probable catalytic subunit of a mannosylinositol phosphorylceramide (MIPC) synthase, CSH1, sphingolipid biosynthesis, mannosyltransferase activity, vacuole (sensu Fungi) |
| 244. |
YGR110W |
3 |
-1.6 |
weak similarity to YLR099c and YDR125c, biological_process unknown, molecular_function unknown, cellular_component unknown |
| 245. |
YNL038W |
2 |
-1.6 |
sequence and functional homologue of human Pig-H protein, GPI15, GPI anchor biosynthesis, molecular_function unknown, cellular_component unknown |
| 246. |
YOL002C |
2 |
-1.4 |
Implicated in Zinc Homeostasis, membran protein, IZH2, lipid metabolism, metal ion binding, membrane |
| 247. |
YGR036C |
1 |
-1.4 |
required for full levels of dolichol-linked oligosaccharides in the endoplasmic reticulum, CAX4, N-linked glycosylation, pyrophosphatase activity, integral to endoplasmic reticulum membrane |
| 248. |
YDR437W |
1 |
-1.1 |
weak similarity to DSCR5b H. sapiens, biological_process unknown, molecular_function unknown, endoplasmic reticulum |
| 249. |
YOL108C |
4 |
-1.1 |
basic helix-loop-helix transcription factor, INO4, positive regulation of transcription from Pol II promoter, specific RNA polymerase II transcription factor activity, nucleus |
| out of 252 |
