Ontology Collection, GO:0005515y protein binding # accession total log(e) description "1", "YAL005C", "2814", "-1099.9", "heat shock protein of HSP70 family, cytosolic, SSA1, protein folding, unfolded protein binding, cytoplasm" "2", "YLL024C", "2712", "-1037.2", "heat shock protein of HSP70 family, cytosolic, SSA2, protein folding, ATP binding, cytoplasm" "3", "YDR212W", "458", "-876.7", "component of chaperonin-containing T-complex, TCP1, protein folding, unfolded protein binding, cytoplasm" "4", "YIL142W", "554", "-865.2", "chaperonin of the TCP1 ring complex, cytosolic, CCT2, protein folding, unfolded protein binding, cytoplasm" "5", "YJL008C", "671", "-836.4", "component of chaperonin-containing T-complex, CCT8, protein folding, unfolded protein binding, cytoplasm" "6", "YJL111W", "527", "-811.5", "component of chaperonin-containing T-complex, CCT7, protein folding, unfolded protein binding, cytoplasm" "7", "YOL004W", "150", "-795.7", "transcription regulatory protein, SIN3, regulation of transcription from Pol II promoter, histone deacetylase activity, histone deacetylase complex" "8", "YJL080C", "865", "-780.9", "required for maintenance of exact ploidy, SCP160, chromosome segregation, RNA binding, endoplasmic reticulum membrane" "9", "YMR186W", "1446", "-769.6", "heat shock protein, HSC82, response to stress, unfolded protein binding, cytoplasm" "10", "YPL240C", "1368", "-699.7", "heat shock protein, HSP82, response to stress, ATPase activity, coupled, cytoplasm" "11", "YNL209W", "1878", "-690.3", "heat shock protein of HSP70 family, cytosolic, SSB2, protein biosynthesis, unfolded protein binding, cytoplasm" "12", "YDL229W", "1946", "-680.7", "heat shock protein of HSP70 family, SSB1, protein biosynthesis, unfolded protein binding, soluble fraction" "13", "YJR064W", "444", "-634.6", "T-complex protein 1, epsilon subunit, CCT5, protein folding, unfolded protein binding, cytoplasm" "14", "YHR027C", "520", "-631.4", "26S proteasome regulatory subunit, RPN1, ubiquitin-dependent protein catabolism, endopeptidase activity, cytoplasm" "15", "YIL075C", "467", "-626", "26S proteasome regulatory subunit, RPN2, ubiquitin-dependent protein catabolism, endopeptidase activity, proteasome regulatory particle (sensu Eukarya)" "16", "YOR326W", "458", "-604.4", "myosin heavy chain, MYO2, establishment of cell polarity (sensu Saccharomyces), microfilament motor activity, actin cap (sensu Fungi)" "17", "YLL026W", "802", "-597.9", "heat shock protein, HSP104, response to stress, chaperone binding, cytoplasm" "18", "YKL022C", "23", "-596.5", "subunit of anaphase-promoting complex (cyclosome), CDC16, ubiquitin-dependent protein catabolism, protein binding, anaphase-promoting complex" "19", "YJL034W", "1363", "-584.6", "nuclear fusion protein, KAR2, response to unfolded protein, unfolded protein binding, endoplasmic reticulum lumen" "20", "YJL014W", "533", "-578.4", "chaperonin of the TCP1 ring complex, cytosolic, CCT3, protein folding, unfolded protein binding, cytoplasm" "21", "YDR188W", "397", "-494.8", "component of chaperonin-containing T-complex (zeta subunit), CCT6, protein folding, unfolded protein binding, cytoplasm" "22", "YDR118W", "22", "-490.6", "subunit of the anaphase promoting complex, APC4, ubiquitin-dependent protein catabolism, protein binding, anaphase-promoting complex" "23", "YLR259C", "1239", "-488.5", "heat shock protein - chaperone, mitochondrial, HSP60, protein folding, single-stranded DNA binding, mitochondrion" "24", "YER110C", "875", "-477.2", "RAN-binding protein, KAP123, protein-nucleus import, protein carrier activity, cytoplasm" "25", "YAL029C", "159", "-457.1", "myosin heavy chain, unconventional (class V) isoform, MYO4, mRNA localization, intracellular, microfilament motor activity, actin cap (sensu Fungi)" "26", "YIL109C", "434", "-446.1", "component of COPII coat of ER-Golgi vesicles, SEC24, ER to Golgi transport, protein binding, COPII vesicle coat" "27", "YDR258C", "345", "-427.2", "heat shock protein of clpb family of ATP-dependent proteases, mitochondrial, HSP78, response to stress, unfolded protein binding, mitochondrial matrix" "28", "YNL250W", "48", "-420.8", "DNA repair protein, RAD50, double-strand break repair via nonhomologous end-joining, protein binding, nucleus" "29", "YIR006C", "303", "-397.3", "actin-cytoskeleton assembly protein, PAN1, endocytosis, protein binding, bridging, plasma membrane" "30", "YNL064C", "918", "-390.5", "mitochondrial and ER import protein, YDJ1, protein-mitochondrial targeting, chaperone regulator activity, cytosol" "31", "YMR116C", "1236", "-389.6", "40S small subunit ribosomal protein, ASC1, biological_process unknown, molecular_function unknown, cytoplasm" "32", "YER103W", "2021", "-387.4", "heat shock protein of HSP70 family, cytosolic, SSA4, response to stress, unfolded protein binding, cytoplasm" "33", "YLR127C", "16", "-376.5", "component of the anaphase promoting complex, APC2, ubiquitin-dependent protein catabolism, protein binding, anaphase-promoting complex" "34", "YBL084C", "29", "-361.8", "subunit of anaphase-promoting complex (cyclosome), CDC27, ubiquitin-dependent protein catabolism, protein binding, anaphase-promoting complex" "35", "YLR442C", "49", "-361.5", "silencing regulatory and DNA-repair protein, SIR3, chromatin silencing, histone binding, nucleolus" "36", "YBL047C", "428", "-334.2", "similarity to mouse eps15R protein, EDE1, endocytosis, molecular_function unknown, bud neck" "37", "YOR027W", "805", "-330.4", "stress-induced protein, STI1, protein folding, unfolded protein binding, cytoplasm" "38", "YML028W", "934", "-324.1", "thiol-specific antioxidant, TSA1, response to oxidative stress, thioredoxin peroxidase activity, cytoplasm" "39", "YDR150W", "260", "-322.7", "nuclear migration protein, NUM1, nuclear migration (sensu Saccharomyces), tubulin binding, bud tip" "40", "YNL138W", "607", "-315.6", "adenylate cyclase-associated protein, 70kDa, SRV2, cytoskeleton organization and biogenesis, cytoskeletal protein binding, actin cortical patch (sensu Fungi)" "41", "YHR064C", "866", "-297.4", "regulator protein involved in pleiotropic drug resistance, SSZ1, protein biosynthesis, unfolded protein binding, cytoplasm" "42", "YKL073W", "166", "-296.9", "chaperone of the ER lumen, LHS1, response to unfolded protein, unfolded protein binding, endoplasmic reticulum lumen" "43", "YHR166C", "22", "-295.7", "subunit of anaphase-promoting complex (cyclosome), CDC23, ubiquitin-dependent protein catabolism, protein binding, anaphase-promoting complex" "44", "YPL139C", "56", "-291.9", "negative regulator of meiosis, UME1, regulation of meiosis, transcription corepressor activity, nucleus" "45", "YER177W", "1051", "-286.1", "14-3-3 protein involved in rapamycin-sensitive signalling, BMH1, sporulation (sensu Fungi), protein binding, nucleus" "46", "YDL132W", "166", "-281.3", "controls G1/S transition, CDC53, ubiquitin-dependent protein catabolism, structural molecule activity, nuclear ubiquitin ligase complex" "47", "YOR298C-A", "438", "-280.4", "multiprotein bridging factor mediates GCN4-dependent transcriptional activation, MBF1, positive regulation of transcription from Pol II promoter, transcription coactivator activity, nucleus" "48", "YJL020C", "337", "-271.5", "similarity to S.pombe hypothetical protein SPAC23A1.16, BBC1, actin cytoskeleton organization and biogenesis, myosin I binding, actin cortical patch (sensu Fungi)" "49", "YLR347C", "429", "-268.8", "karyopherin-beta, KAP95, protein-nucleus import, protein carrier activity, cytoplasm" "50", "YDR099W", "981", "-268.7", "suppressor of clathrin deficiency, BMH2, sporulation (sensu Fungi), protein binding, nucleus" "51", "YLL039C", "903", "-266.3", "ubiquitin, UBI4, response to stress, ATP-dependent protein binding, cytoplasm" "52", "YCR088W", "681", "-262.8", "actin-binding protein, ABP1, establishment of cell polarity (sensu Saccharomyces), protein binding, cytoplasm" "53", "YGR285C", "711", "-255.1", "zuotin, a putative Z-DNA binding protein, ZUO1, protein folding, unfolded protein binding, cytoplasm" "54", "YMR308C", "362", "-241.2", "beta karyopherin, PSE1, mRNA-nucleus export, protein carrier activity, cytoplasm" "55", "YNL007C", "578", "-237.5", "heat shock protein, SIS1, translational initiation, unfolded protein binding, cytosolic small ribosomal subunit (sensu Eukarya)" "56", "YEL034W", "875", "-236.1", "translation initiation factor eIF5A.1, HYP2, translational initiation, protein binding, cytoplasm" "57", "YDR129C", "737", "-235.4", "actin filament bundling protein, fimbrin, SAC6, actin filament organization, protein binding, bridging, actin cortical patch (sensu Fungi)" "58", "YNL330C", "88", "-235.2", "histone deacetylase B, RPD3, chromatin silencing at telomere, histone deacetylase activity, histone deacetylase complex" "59", "YMR092C", "368", "-234.4", "actin cytoskeleton component, AIP1, response to osmotic stress, protein binding, cytoplasm" "60", "YGR040W", "143", "-232.1", "ser/thr protein kinase of the MAP kinase family, KSS1, protein amino acid phosphorylation, MAP kinase activity, nucleus" "61", "YDL013W", "17", "-229.3", "hexose metabolism-related protein, HEX3, sporulation (sensu Fungi), DNA binding, nucleus" "62", "YGR218W", "414", "-228.6", "nuclear export factor, exportin, CRM1, mRNA-nucleus export, protein carrier activity, nucleus" "63", "YDR335W", "95", "-224.7", "multicopy supressor of snf1 mutation, MSN5, protein-nucleus export, protein binding, nucleus" "64", "YPL048W", "658", "-220.7", "translation elongation factor eEF1 gamma homologue, CAM1, regulation of translational elongation, translation elongation factor activity, cytosolic ribosome (sensu Eukarya)" "65", "YBL075C", "1962", "-218.1", "heat shock protein of HSP70 family, cytosolic, SSA3, response to stress, ATPase activity, cytosol" "66", "YLR429W", "312", "-216.9", "a coronin, that promotes actin polymerization and crosslinking to microtubules, CRN1, actin filament organization, protein binding, bridging, actin cortical patch (sensu Fungi)" "67", "YOR249C", "17", "-214.6", "component of the anaphase-promoting complex, APC5, ubiquitin-dependent protein catabolism, protein binding, anaphase-promoting complex" "68", "YOR230W", "612", "-212.6", "transcriptional modulator, WTM1, regulation of meiosis, transcription corepressor activity, nucleus" "69", "YBR072W", "671", "-207.9", "heat shock protein, HSP26, response to stress, unfolded protein binding, cytoplasm" "70", "YEL056W", "50", "-204.8", "subunit of the major yeast histone acetyltransferase, HAT2, chromatin silencing at telomere, H3/H4 histone acetyltransferase activity, cytoplasm" "71", "YJR070C", "521", "-203.9", "protein that binds to the C-terminal domain of Hyp2p (eIF5A), LIA1, biological_process unknown, protein binding, cytoplasm" "72", "YMR275C", "46", "-203.1", "ubiquitination pathway protein, BUL1, protein monoubiquitination, protein binding, plasma membrane" "73", "YML048W", "302", "-201.1", "involved in glucose repression, GSF2, secretory pathway, molecular_function unknown, cytoplasm" "74", "YIL046W", "62", "-200.4", "involved in regulation of sulfur assimilation genes and cell cycle progression, MET30, ubiquitin-dependent protein catabolism, protein binding, nuclear ubiquitin ligase complex" "75", "YLR216C", "590", "-193.3", "member of the cyclophilin family, CPR6, protein folding, unfolded protein binding, cytoplasm" "76", "YHL030W", "195", "-191", "involved in cell wall biogenesis and architecture, ECM29, protein catabolism, protein binding, cytoplasm" "77", "YDL084W", "776", "-187.8", "probably involved in pre-mRNA splicing, SUB2, mRNA-nucleus export, protein binding, nucleus" "78", "YBL007C", "226", "-187.4", "cytoskeleton assembly control protein, SLA1, cell wall organization and biogenesis, protein binding, bridging, actin cortical patch (sensu Fungi)" "79", "YOR229W", "32", "-186.6", "transcriptional modulator, WTM2, regulation of meiosis, transcription corepressor activity, nucleus" "80", "YER125W", "280", "-184.2", "hect domain E3 ubiquitin-protein ligase, RSP5, protein monoubiquitination, ubiquitin-protein ligase activity, ubiquitin ligase complex" "81", "YML064C", "71", "-182.6", "GTP-binding protein of the RAS superfamily, TEM1, signal transduction, protein binding, spindle pole body" "82", "YDR189W", "204", "-182.2", "hydrophilic suppressor of YPT1 and member of the Sec1p family, SLY1, ER to Golgi transport, SNARE binding, endoplasmic reticulum" "83", "YGR211W", "369", "-181.3", "similarity to M.musculus zinc finger protein ZPR1, ZPR1, regulation of cell cycle, protein binding, cytoplasm" "84", "YNL084C", "121", "-180.2", "required for endocytosis and cytoskeletal organization, END3, actin filament organization, protein binding, bridging, actin cortical patch (sensu Fungi)" "85", "YCR009C", "325", "-176.5", "similarity to human amphiphysin and Rvs167p, RVS161, endocytosis, cytoskeletal protein binding, actin cortical patch (sensu Fungi)" "86", "YHR052W", "241", "-174.8", "adaptor protein specifically linking the 26S proteasome to its substrate, the SCF component Cdc4, CIC1, protein catabolism, protein binding, bridging, nucleolus" "87", "YBR112C", "192", "-173.9", "general repressor of transcription, CYC8, negative regulation of transcription, transcription coactivator activity, nucleus" "88", "YEL013W", "173", "-172.8", "required for vacuole inheritance and protein targeting from the cytoplasm to vacuole, VAC8, protein-vacuolar targeting, protein binding, vacuole (sensu Fungi)" "89", "YDR533C", "228", "-169.8", "strong similarity to hypothetical proteins YPL280w, YOR391c and YMR322c, HSP31, biological_process unknown, unfolded protein binding, soluble fraction" "90", "YGR193C", "200", "-166.3", "pyruvate dehydrogenase complex protein X, PDX1, acetyl-CoA biosynthesis from pyruvate, protein binding, mitochondrion" "91", "YPL049C", "131", "-161.8", "MAP kinase-associated protein, down-regulator of invasive growth and mating, DIG1, invasive growth (sensu Saccharomyces), transcription factor binding, nucleus" "92", "YKL213C", "116", "-161.8", "involved in ubiquitin-dependent proteolysis, DOA1, ubiquitin-dependent protein catabolism, molecular_function unknown, cytoplasm" "93", "YLR378C", "217", "-160.2", "ER protein-translocation complex subunit, SEC61, protein-ER targeting, protein transporter activity, integral to endoplasmic reticulum membrane" "94", "YLL050C", "634", "-155.2", "cofilin, actin binding and severing protein, COF1, actin filament organization, protein binding, actin cortical patch (sensu Fungi)" "95", "YER048C", "219", "-155", "dnaJ homolog, CAJ1, biological_process unknown, chaperone regulator activity, cellular_component unknown" "96", "YKR048C", "510", "-155", "nucleosome assembly protein I, NAP1, bud growth, protein binding, cytoplasm" "97", "YJL128C", "56", "-154.8", "tyrosine protein kinase of the MAP kinase kinase family, PBS2, protein amino acid phosphorylation, MAP kinase kinase activity, cytoplasm" "98", "YJR074W", "44", "-153.3", "required for nuclear-protein import, GSP1-interacting, MOG1, protein-nucleus import, RAN protein binding, nucleus" "99", "YPL195W", "142", "-151.2", "AP-3 complex subunit, gamma-adaptin, 107 KD, APL5, Golgi to vacuole transport, molecular_function unknown, AP-3 adaptor complex" "100", "YBL050W", "311", "-149.8", "transport vesicle fusion protein, SEC17, ER to Golgi transport, soluble NSF attachment protein activity, peripheral to membrane of membrane fraction" "101", "YDR388W", "309", "-146.9", "reduced viability upon starvation protein, RVS167, endocytosis, cytoskeletal protein binding, actin cortical patch (sensu Fungi)" "102", "YDL143W", "528", "-146.5", "component of chaperonin-containing T-complex, CCT4, protein folding, unfolded protein binding, cytoplasm" "103", "YDL059C", "6", "-144.3", "recombination and DNA repair protein, RAD59, telomerase-independent telomere maintenance, protein binding, nucleus" "104", "YOR035C", "40", "-143.7", "required for mother cell-specific gene expression, SHE4, actin cytoskeleton organization and biogenesis, myosin binding, cytoplasm" "105", "YGL238W", "180", "-142", "importin-beta-like protein, CSE1, protein-nucleus export, importin-alpha export receptor activity, nuclear membrane" "106", "YER120W", "439", "-141.5", "required for inositol metabolism, SCS2, chromatin silencing at telomere, protein binding, endoplasmic reticulum" "107", "YDR328C", "184", "-141.3", "kinetochore protein complex CBF3, subunit D, SKP1, ubiquitin-dependent protein catabolism, protein binding, cytoplasm" "108", "YDR369C", "26", "-139", "DNA repair protein, XRS2, double-strand break repair via nonhomologous end-joining, protein binding, nucleus" "109", "YOR122C", "356", "-137.4", "profilin, PFY1, response to osmotic stress, actin monomer binding, contractile ring (sensu Saccharomyces)" "110", "YKL196C", "372", "-137", "SNARE protein for Endoplasmic Reticulum-Golgi transport, YKT6, intra-Golgi transport, v-SNARE activity, membrane" "111", "YNL079C", "436", "-135.4", "tropomyosin 1, TPM1, establishment of cell polarity (sensu Saccharomyces), actin lateral binding, contractile ring (sensu Saccharomyces)" "112", "YLR182W", "53", "-135.3", "transcription factor, SWI6, meiosis, protein binding, cytoplasm" "113", "YDR168W", "260", "-121.5", "cell division control protein, CDC37, signal transduction, unfolded protein binding, cytoplasm" "114", "YDR395W", "274", "-121.2", "putative beta-karyopherin, SXM1, mRNA-nucleus export, protein carrier activity, nucleus" "115", "YBR155W", "63", "-120.5", "weak similarity to stress-induced STI1p, CNS1, protein folding, unfolded protein binding, cytoplasm" "116", "YPL037C", "468", "-118.5", "GAL4 DNA-binding enhancer protein, EGD1, nascent polypeptide association, unfolded protein binding, cytosolic ribosome (sensu Eukarya)" "117", "YBR109C", "443", "-118.4", "calmodulin, CMD1, cytoskeleton organization and biogenesis, calcium ion binding, cytoplasm" "118", "YJL117W", "124", "-117.2", "targeting and packing of Pho84p inorganic phospate transporter, PHO86, secretory pathway, molecular_function unknown, endoplasmic reticulum" "119", "YOR232W", "198", "-116", "heat shock protein - chaperone, MGE1, mitochondrial matrix protein import, unfolded protein binding, mitochondrion" "120", "YJR066W", "97", "-115.9", "phosphatidylinositol 3-kinase, TOR1, meiosis, protein binding, plasma membrane" "121", "YHR193C", "598", "-115.4", "alpha subunit of the nascent polypeptide-associated complex, EGD2, nascent polypeptide association, unfolded protein binding, nascent polypeptide-associated complex" "122", "YLL001W", "209", "-110.5", "dynamin-related protein, DNM1, mitochondrial fission, GTPase activity, mitochondrial outer membrane" "123", "YKR036C", "40", "-110.2", "CCR4 associated factor, CAF4, regulation of transcription, DNA-dependent, protein binding, CCR4-NOT complex" "124", "YMR061W", "59", "-109", "component of pre-mRNA 3^-end processing factor CF I, RNA14, mRNA polyadenylylation, cleavage and polyadenylylation specificity factor activity, nucleus" "125", "YMR183C", "189", "-107.4", "syntaxin (T-SNARE), SSO2, vesicle fusion, t-SNARE activity, cytoplasm" "126", "YNL243W", "314", "-107.2", "cytoskeleton assembly control protein, SLA2, cell wall organization and biogenesis, protein binding, bridging, actin cortical patch (sensu Fungi)" "127", "YPL001W", "57", "-104.9", "histone acetyltransferase subunit, HAT1, chromatin silencing at telomere, H3/H4 histone acetyltransferase activity, cytoplasm" "128", "YGL106W", "427", "-104.9", "Myo2p light chain, MLC1, establishment of cell polarity (sensu Saccharomyces), microfilament motor activity, actin cap (sensu Fungi)" "129", "YIL034C", "173", "-104.2", "F-actin capping protein, beta subunit, CAP2, cell wall organization and biogenesis, protein binding, actin cortical patch (sensu Fungi)" "130", "YDR214W", "295", "-103.7", "stress-regulated cochaperone , AHA1, response to stress, chaperone activator activity, cytoplasm" "131", "YDL160C", "397", "-103.1", "putative RNA helicase of the DEAD box family, DHH1, deadenylylation-dependent decapping, protein binding, cytoplasm" "132", "YGL016W", "100", "-102.7", "Member of the karyopherin-beta family, nuclear import, KAP122, protein-nucleus import, protein carrier activity, cytoplasm" "133", "YLR206W", "127", "-101.7", "clathrin binding protein, required for endocytosis, ENT2, actin filament organization, clathrin binding, actin cortical patch (sensu Fungi)" "134", "YNL189W", "362", "-101.3", "karyopherin-alpha or importin, SRP1, nucleocytoplasmic transport, protein carrier activity, cytoplasm" "135", "YER093C", "19", "-99.6", "lipid biosynthesis, binding of TOR, TSC11, sphingolipid biosynthesis, protein binding, cellular_component unknown" "136", "YJL047C", "30", "-98.7", "weak similarity to Cdc53p, RTT101, ubiquitin-dependent protein catabolism, protein binding, cytoplasm" "137", "YEL037C", "314", "-97.2", "nucleotide excision repair protein (ubiquitin-like protein), RAD23, nucleotide-excision repair, DNA damage recognition, damaged DNA binding, repairosome" "138", "YDL178W", "123", "-95", "D-lactate dehydrogenase, DLD2, biological_process unknown, D-lactate dehydrogenase (cytochrome) activity, mitochondrial matrix" "139", "YOR020C", "488", "-93.6", "chaperonin, mitochondrial, HSP10, protein folding, unfolded protein binding, mitochondrial matrix" "140", "YOL018C", "23", "-93", "member of the syntaxin family of t-SNAREs, TLG2, vesicle fusion, v-SNARE activity, Golgi trans face" "141", "YDR499W", "73", "-90.2", "cell cycle checkpoint protein, LCD1, telomerase-dependent telomere maintenance, protein binding, nuclear chromosome" "142", "YNL103W", "61", "-86.3", "transcriptional activator of sulfur metabolism, MET4, positive regulation of transcription from Pol II promoter, transcription coactivator activity, nucleus" "143", "YLL021W", "150", "-86.2", "involved in cell polarity, SPA2, establishment of cell polarity (sensu Saccharomyces), cytoskeletal regulatory protein binding, bud neck" "144", "YPL181W", "29", "-83.9", "Cyc8-Tup1 Interacting protein, CTI6, positive regulation of transcription, transcription factor binding, nucleus" "145", "YML055W", "44", "-83", "signal peptidase 18 KD subunit, SPC2, signal peptide processing, protein binding, signal peptidase complex" "146", "YFL016C", "121", "-82.6", "heat shock protein - chaperone, MDJ1, protein folding, unfolded protein binding, mitochondrial inner membrane" "147", "YJR125C", "201", "-82.5", "cytoskeletal adaptor, ENT3, actin filament organization, protein binding, actin cortical patch (sensu Fungi)" "148", "YLR026C", "68", "-80.6", "syntaxin (T-SNARE), SED5, ER to Golgi transport, t-SNARE activity, Golgi cis-face" "149", "YOL078W", "36", "-79.4", "similarity to stress activated MAP kinase interacting protein S. pombe, AVO1, regulation of cell growth, molecular_function unknown, cytoplasm" "150", "YNL097C", "20", "-79", "involved in transcriptional regulation of PHO5, PHO23, chromatin modification, histone deacetylase activity, nucleus" "151", "YDR171W", "250", "-78.2", "heat shock protein, HSP42, response to stress, unfolded protein binding, cytoplasm" "152", "YNL172W", "50", "-77.8", "subunit of anaphase-promoting complex (cyclosome), APC1, ubiquitin-dependent protein catabolism, protein binding, anaphase-promoting complex" "153", "YGL241W", "57", "-76", "Member of the karyopherin-beta family, nuclear import, KAP114, protein-nucleus import, protein carrier activity, cytoplasm" "154", "YOR239W", "154", "-74.7", "questionable ORF, ABP140, actin cytoskeleton organization and biogenesis, protein binding, bridging, actin filament" "155", "YMR214W", "88", "-74.6", "homolog of E. coli DnaJ, functions in the endoplasmic reticulum by interaction with Kar2p, SCJ1, protein folding, chaperone binding, endoplasmic reticulum lumen" "156", "YDR372C", "133", "-74.1", "similarity to hypothetical S. pombe protein, VPS74, protein-vacuolar targeting, molecular_function unknown, cytoplasm" "157", "YDL065C", "56", "-72.3", "required for biogenesis of peroxisomes - peroxin, PEX19, peroxisome organization and biogenesis, molecular_function unknown, cytosol" "158", "YNL281W", "212", "-72.2", "strong similarity to YDR214w, HCH1, response to stress, chaperone activator activity, cytoplasm" "159", "YER009W", "276", "-71.4", "nuclear transport factor, NTF2, protein-nucleus import, RAN protein binding, nuclear membrane" "160", "YGR048W", "66", "-71.3", "ubiquitin fusion degradation protein, UFD1, ubiquitin-dependent protein catabolism, protein binding, endoplasmic reticulum" "161", "YJR090C", "18", "-70", "required for glucose repression and for glucose and cation transport, GRR1, ubiquitin-dependent protein catabolism, protein binding, cytoplasm" "162", "YLR080W", "23", "-69.8", "strong similarity to Emp47p, EMP46, ER to Golgi transport, molecular_function unknown, Golgi membrane" "163", "YKL205W", "103", "-69.6", "pre-tRNA splicing protein, LOS1, tRNA-nucleus export, tRNA binding, nuclear matrix" "164", "YKL007W", "175", "-69.4", "F-actin capping protein alpha subunit, CAP1, cell wall organization and biogenesis, protein binding, actin cortical patch (sensu Fungi)" "165", "YGL020C", "102", "-69.1", "weak similarity to TRCDSEMBL:SPBC543_10 putative coiled-coil protein S. pombe, MDM39, mitochondrion organization and biogenesis, molecular_function unknown, endoplasmic reticulum" "166", "YLR002C", "160", "-68.5", "required for maturation and intranuclear transport of pre-ribosomes, NOC3, rRNA processing, protein binding, nucleus" "167", "YHR005C-A", "138", "-68.1", "subunit of the Tim22-complex, MRS11, mitochondrial inner membrane protein import, unfolded protein binding, mitochondrial intermembrane space" "168", "YIL026C", "51", "-68.1", "nuclear cohesin protein, IRR1, mitotic sister chromatid cohesion, protein binding, nuclear cohesin complex" "169", "YPL169C", "153", "-68", "factor for nuclear mRNA export, MEX67, mRNA-nucleus export, protein binding, cytoplasm" "170", "YDL207W", "17", "-67", "RNA export mediator, GLE1, poly(A)+ mRNA-nucleus export, molecular_function unknown, nuclear pore" "171", "YIR004W", "64", "-65.7", "DnaJ-like protein involved specifically in peroxisomal protein import, DJP1, peroxisome matrix protein import, chaperone binding, cytosol" "172", "YHR170W", "264", "-65.5", "nonsense-mediated mRNA decay protein, NMD3, ribosomal large subunit assembly and maintenance, protein binding, cytosol" "173", "YPL232W", "131", "-65.4", "syntaxin-related protein, SSO1, vesicle fusion, t-SNARE activity, integral to plasma membrane" "174", "YDR002W", "381", "-65.1", "ran-specific GTPase-activating protein, YRB1, ubiquitin-dependent protein catabolism, RAN protein binding, cytoplasm" "175", "YPR049C", "28", "-65.1", "peripheral membrane protein required forstable binding of precursor API to its target membrane, ATG11, protein-vacuolar targeting, molecular_function unknown, extrinsic to membrane" "176", "YDR227W", "42", "-64.9", "silencing regulatory and DNA-repair protein, SIR4, chromatin silencing, histone binding, nuclear telomere cap complex" "177", "YOR145C", "150", "-64.6", "strong similarity to hypothtical S. pombe protein and to hypothetical C. elegans protein, PNO1, rRNA processing, unfolded protein binding, nucleus" "178", "YPR029C", "107", "-64.4", "AP-1 complex subunit, gamma-adaptin, 94 KD, APL4, vesicle-mediated transport, clathrin binding, AP-1 adaptor complex" "179", "YDL226C", "269", "-64.1", "ADP-ribosylation factor GTPase-activating protein (ARF-GAP), GCS1, ER to Golgi transport, ARF GTPase activator activity, cytoskeleton" "180", "YIL138C", "214", "-63.3", "tropomyosin, isoform 2, TPM2, establishment of cell polarity (sensu Saccharomyces), actin lateral binding, contractile ring (sensu Saccharomyces)" "181", "YLR186W", "241", "-62", "strong similarity to S.pombe hypothetical protein C18G6.07C, EMG1, processing of 20S pre-rRNA, snoRNA binding, cytoplasm" "182", "YKL117W", "337", "-61.9", "Hsp90 (Ninety) Associated Co-chaperone, SBA1, protein folding, chaperone binding, cytoplasm" "183", "YPR101W", "7", "-61.4", "splicing factor, SNT309, nuclear mRNA splicing, via spliceosome, molecular_function unknown, spliceosome complex" "184", "YCL044C", "35", "-61.1", "similarity to hypothetical protein K. lactis, biological_process unknown, molecular_function unknown, mitochondrion" "185", "YLR148W", "80", "-61.1", "vacuolar membrane protein, PEP3, late endosome to vacuole transport, protein binding, vacuolar membrane (sensu Fungi)" "186", "YDL161W", "70", "-60.4", "clathrin binding protein, required for endocytosis, ENT1, actin filament organization, clathrin binding, actin cortical patch (sensu Fungi)" "187", "YDR498C", "13", "-60", "secretory pathway protein, SEC20, vesicle fusion, v-SNARE activity, endoplasmic reticulum" "188", "YLR055C", "52", "-59.7", "transcriptional adaptor or co-activator, SPT8, histone acetylation, transcription cofactor activity, nucleus" "189", "YLR268W", "67", "-59.3", "synaptobrevin (V-SNARE), SEC22, ER to Golgi transport, v-SNARE activity, endoplasmic reticulum" "190", "YLR449W", "301", "-58.1", "nucleolar peptidylprolyl cis-trans isomerase (PPIase), FPR4, biological_process unknown, peptidyl-prolyl cis-trans isomerase activity, nucleus" "191", "YER030W", "26", "-57.6", "similarity to mouse nucleolin, biological_process unknown, molecular_function unknown, nucleus" "192", "YLR421C", "230", "-57", "weak similarity to human 42K membrane glycoprotein, RPN13, proteolysis and peptidolysis, endopeptidase activity, proteasome regulatory particle (sensu Eukarya)" "193", "YMR096W", "81", "-56.4", "stationary phase protein, SNZ1, pyridoxine metabolism, protein binding, cellular_component unknown" "194", "YKL203C", "96", "-55.9", "phosphatidylinositol 3-kinase, TOR2, signal transduction, protein binding, plasma membrane" "195", "YGR080W", "113", "-55.9", "twinfilin, an actin monomer sequestering protein, TWF1, polar budding, actin monomer binding, actin cortical patch (sensu Fungi)" "196", "YHR060W", "44", "-53.9", "vacuolar ATPase assembly protein, VMA22, protein complex assembly, unfolded protein binding, endoplasmic reticulum membrane" "197", "YJR132W", "69", "-53.8", "Nam7p interacting protein, NMD5, protein-nucleus import, protein carrier activity, cytoplasm" "198", "YDL201W", "138", "-52.7", "part of complex required for 7-methylguanosine modification , TRM8, tRNA methylation, protein binding, nucleus" "199", "YDR165W", "153", "-52.3", "weak similarity to hypothetical C.elegans protein, TRM82, tRNA methylation, protein binding, nucleus" "200", "YMR197C", "40", "-52.2", "v-SNARE: involved in Golgi retrograde protein traffic, VTI1, intra-Golgi transport, v-SNARE activity, integral to Golgi membrane" "201", "YOR370C", "87", "-52.2", "geranylgeranyltransferase regulatory subunit, MRS6, intracellular protein transport, Rab escort protein activity, cytoplasm" "202", "YPR028W", "104", "-52", "Ypt-interacting protein, YOP1, membrane organization and biogenesis, molecular_function unknown, membrane" "203", "YDR153C", "37", "-52", "epsin-related protein required for golgi-endosome traffic , ENT5, Golgi to endosome transport, clathrin binding, cytoplasm" "204", "YPL010W", "100", "-51.5", "coatomer complex zeta chain, RET3, retrograde transport, Golgi to ER, protein binding, COPI vesicle coat" "205", "YML013W", "36", "-50.9", "hypothetical protein, SEL1, protein secretion, molecular_function unknown, endoplasmic reticulum" "206", "YIL005W", "68", "-50.5", "disulfide-isomerase , EPS1, protein-ER retention, protein disulfide isomerase activity, endoplasmic reticulum membrane" "207", "YLR319C", "52", "-50.4", "bud site selection protein, BUD6, establishment of cell polarity (sensu Saccharomyces), cytoskeletal regulatory protein binding, actin cap (sensu Fungi)" "208", "YHR083W", "34", "-50.3", "sorting and assembly machinery (SAM) complex subunit, SAM35, mitochondrial outer membrane protein import, protein binding, mitochondrial outer membrane" "209", "YMR115W", "54", "-50.3", "similarity to YKL133c, FMP24, biological_process unknown, molecular_function unknown, mitochondrion" "210", "YML094W", "181", "-48.7", "Gim complex component, GIM5, tubulin folding, tubulin binding, cytoplasm" "211", "YJL154C", "115", "-48.3", "protein-sorting protein, vacuolar, VPS35, protein-Golgi retention, molecular_function unknown, endosome" "212", "YLR200W", "189", "-48.3", "Gim complex component, YKE2, protein folding, tubulin binding, cytoplasm" "213", "YHR108W", "235", "-48.2", "Arf-binding protein, GGA2, Golgi to vacuole transport, molecular_function unknown, Golgi trans face" "214", "YEL003W", "34", "-48.1", "Gim complex component, GIM4, tubulin folding, tubulin binding, cytoplasm" "215", "YEL020W-A", "173", "-47.6", "essential subunit of the TIM22-complex for mitochondrial protein import, TIM9, mitochondrial inner membrane protein import, unfolded protein binding, mitochondrial intermembrane space" "216", "YJL085W", "37", "-47.3", "70 kDa exocyst component protein, EXO70, cytokinesis, protein binding, exocyst" "217", "YNR006W", "50", "-47.2", "vacuolar protein sorting-associated protein, VPS27, protein-Golgi retention, protein binding, endosome" "218", "YNL311C", "19", "-47.1", "hypothetical protein, ubiquitin-dependent protein catabolism, protein binding, ubiquitin ligase complex" "219", "YHR014W", "5", "-46.8", "meiosis-specific protein, SPO13, positive regulation of sister chromatid cohesion, protein binding, nucleus" "220", "YJL180C", "18", "-45.9", "F1F0-ATPase complex assembly protein, ATP12, protein complex assembly, unfolded protein binding, mitochondrial matrix" "221", "YPR032W", "94", "-44.7", "polarized exocytosis by regulating SNARE function, SRO7, exocytosis, molecular_function unknown, plasma membrane" "222", "YNL006W", "32", "-44.2", "required for transport of permeases from the golgi to the plasma membrane, LST8, transport, protein binding, Golgi membrane" "223", "YNL206C", "44", "-44.2", "similarity to structure-specific recognition proteins, RTT106, negative regulation of DNA transposition, molecular_function unknown, nucleus" "224", "YDR086C", "186", "-43.8", "ER protein-translocase complex subunit, SSS1, cotranslational membrane targeting, protein transporter activity, translocon" "225", "YFR051C", "179", "-43.4", "coatomer complex delta chain, RET2, ER to Golgi transport, protein binding, COPI vesicle coat" "226", "YBR135W", "40", "-43.2", "cyclin-dependent kinases regulatory subunit, CKS1, regulation of cell cycle, protein kinase activator activity, cytoplasm" "227", "YHR016C", "107", "-42.5", "strong similarity to hypothetical protein YFR024c-a, YSC84, actin filament organization, molecular_function unknown, actin cortical patch (sensu Fungi)" "228", "YKL135C", "103", "-42.5", "AP-1 complex subunit, beta1-adaptin, 82 KD, APL2, vesicle-mediated transport, clathrin binding, AP-1 adaptor complex" "229", "YOR327C", "90", "-42.1", "synaptobrevin (v-SNARE) homolog present on post-Golgi vesicles, SNC2, endocytosis, v-SNARE activity, transport vesicle" "230", "YMR276W", "146", "-41.3", "ubiquitin-like protein, DSK2, spindle pole body duplication (sensu Saccharomyces), protein binding, bridging, nucleus" "231", "YGL153W", "108", "-41.1", "peroxisomal protein involved in protein import - peroxin, PEX14, protein-peroxisome targeting, protein binding, peroxisomal membrane" "232", "YDR358W", "93", "-40.3", "Arf-binding protein; involved in trafficking of proteins, GGA1, Golgi to vacuole transport, molecular_function unknown, Golgi trans face" "233", "YPL094C", "40", "-40.2", "ER protein-translocation complex subunit, SEC62, SRP-dependent cotranslational membrane targeting, translocation, protein binding, endoplasmic reticulum membrane" "234", "YER083C", "79", "-40.1", "hypothetical protein, RMD7, cell wall organization and biogenesis, molecular_function unknown, endoplasmic reticulum" "235", "YBL101C", "65", "-39.6", "involved in cell wall biogenesis and architecture, ECM21, cell wall organization and biogenesis, molecular_function unknown, cytoplasm" "236", "YJL104W", "36", "-39.5", "Presequence translocase-Asssociated Motor, constituent of the mitochondrial import motor PAM, PAM16, mitochondrial matrix protein import, protein binding, mitochondrion" "237", "YJR093C", "68", "-38.6", "component of pre-mRNA polyadenylation factor PF I, FIP1, mRNA polyadenylylation, cleavage and polyadenylylation specificity factor activity, mRNA cleavage and polyadenylation specificity factor complex" "238", "YIL159W", "47", "-38.5", "regulator of budding, BNR1, actin filament organization, cytoskeletal protein binding, contractile ring (sensu Saccharomyces)" "239", "YNL229C", "53", "-38.5", "nitrogen catabolite repression regulator, URE2, regulation of nitrogen utilization, transcription corepressor activity, soluble fraction" "240", "YPL082C", "99", "-38.5", "transcriptional accessory protein, MOT1, regulation of transcription from Pol II promoter, ATPase activity, nuclear chromosome" "241", "YMR192W", "49", "-38", "similarity to mouse Tbc1 protein, APP2, actin filament organization, molecular_function unknown, cytoplasm" "242", "YGL095C", "46", "-37", "vacuolar protein sorting-associated protein, VPS45, protein complex assembly, unfolded protein binding, cytosol" "243", "YLR166C", "66", "-37", "required for exocytosis, SEC10, establishment of cell polarity (sensu Saccharomyces), protein binding, exocyst" "244", "YBR202W", "48", "-36.5", "cell division control protein, CDC47, DNA replication initiation, chromatin binding, cytoplasm" "245", "YNL271C", "57", "-35.4", "regulator of budding, BNI1, establishment of cell polarity (sensu Saccharomyces), cytoskeletal regulatory protein binding, bud neck" "246", "YHL031C", "41", "-35.3", "SNARE protein of Golgi compartment, GOS1, intra-Golgi transport, v-SNARE activity, integral to membrane" "247", "YDR164C", "124", "-35", "protein transport protein, SEC1, vesicle fusion, SNARE binding, bud neck" "248", "YMR039C", "65", "-34.3", "transcriptional coactivator, SUB1, positive regulation of transcription from Pol II promoter, transcription coactivator activity, nucleus" "249", "YNL246W", "26", "-33.9", "similarity to D.melanogaster SET protein, VPS75, protein-vacuolar targeting, molecular_function unknown, nucleus" "250", "YOR057W", "58", "-33.4", "subunit of SCF ubiquitin ligase complex, SGT1, protein complex assembly, chaperone binding, ubiquitin ligase complex" "251", "YNL310C", "23", "-33.4", "similarity to S.pombe hypothetical protein SPAC24H6.02c, FMP28, biological_process unknown, molecular_function unknown, mitochondrion" "252", "YJL029C", "18", "-33.3", "subunit of VP51-54 complex, required for protein sorting at the yeast late Golgi, VPS53, Golgi to vacuole transport, molecular_function unknown, cytoplasm" "253", "YMR264W", "27", "-33.3", "involved in ubiquitination and degradation at the ER surface, CUE1, ER-associated protein catabolism, protein binding, integral to endoplasmic reticulum membrane" "254", "YOR018W", "31", "-33", "O-dinitrobenzene, calcium and zinc resistance protein, ROD1, response to drug, molecular_function unknown, plasma membrane" "255", "YBR014C", "36", "-32.9", "similarity to glutaredoxin, biological_process unknown, molecular_function unknown, vacuole (sensu Fungi)" "256", "YDR480W", "19", "-32.7", "MAP kinase-associated protein, down-regulator of invasive growth and mating, DIG2, invasive growth (sensu Saccharomyces), transcription factor binding, nucleus" "257", "YBR102C", "50", "-32.3", "exocyst protein essential for secretion, EXO84, exocytosis, protein binding, bud neck" "258", "YNL153C", "109", "-32.2", "Gim complex component, GIM3, tubulin folding, tubulin binding, cytoplasm" "259", "YMR060C", "24", "-32.2", "mitochondrial outer membrane import receptor subunit, 37 kD, TOM37, outer mitochondrial membrane organization and biogenesis, protein binding, mitochondrial sorting and assembly machinery complex" "260", "YLR263W", "16", "-31.8", "meiosis-specific protein, synaptonemal protein, RED1, synaptonemal complex formation, molecular_function unknown, synaptonemal complex" "261", "YLR025W", "208", "-31.5", "class E Vps protein, SNF7, late endosome to vacuole transport, molecular_function unknown, cytoplasm" "262", "YER044C", "77", "-30.6", "involved in synthesis of ergosterol, ERG28, ergosterol biosynthesis, molecular_function unknown, endoplasmic reticulum membrane" "263", "YLR337C", "81", "-30.6", "verprolin, VRP1, actin filament organization, actin binding, actin cortical patch (sensu Fungi)" "264", "YKL204W", "120", "-30", "translation initiation factor 4E-associated protein, EAP1, negative regulation of translation, molecular_function unknown, mRNA cap complex" "265", "YOR098C", "84", "-30", "nuclear pore protein, NUP1, mRNA-nucleus export, protein binding, nuclear pore" "266", "YDR244W", "16", "-29.9", "peroxisomal targeting signal receptor, PEX5, peroxisome organization and biogenesis, peroxisome targeting sequence binding, cytosol" "267", "YLR369W", "104", "-29.9", "mitochondrial heat shock protein 70, SSQ1, DNA-dependent DNA replication, unfolded protein binding, mitochondrial matrix" "268", "YGR078C", "66", "-29.7", "GIM4 - Gim complex component, PAC10, tubulin folding, tubulin binding, cytoplasm" "269", "YLR093C", "64", "-29.4", "v-SNARE, vacuolar, NYV1, vesicle fusion, v-SNARE activity, vacuolar membrane" "270", "YKL006C-A", "19", "-29.2", "SNARE-like protein, SFT1, intra-Golgi transport, v-SNARE activity, Golgi membrane" "271", "YOR265W", "170", "-29.2", "beta-tubulin binding protein, RBL2, post-chaperonin tubulin folding pathway, tubulin binding, cytoplasm" "272", "YDR079W", "13", "-29.1", "cytochrome-c oxidase assembly protein, PET100, aerobic respiration, unfolded protein binding, mitochondrial inner membrane" "273", "YOR056C", "90", "-28.9", "weak similarity to human phosphorylation regulatory protein HP-10, NOB1, ubiquitin-dependent protein catabolism, unfolded protein binding, nucleus" "274", "YAL058W", "20", "-28.8", "calnexin, involved in regulation of secretion, CNE1, ER-associated protein catabolism, molecular_function unknown, integral to endoplasmic reticulum membrane" "275", "YIL068C", "28", "-28.3", "protein transport protein, SEC6, cytokinesis, protein binding, bud tip" "276", "YDR320C", "58", "-27.9", "clathrin-binding protein required for normal clathrin function and for uncoating of clathrin-coated vesicles, SWA2, ER organization and biogenesis, molecular_function unknown, endoplasmic reticulum membrane" "277", "YGL161C", "29", "-27.8", "weak similarity to TRCDSEMBL:HS167A19_1 dJ167A19.1 human, YIP5, vesicle-mediated transport, Rab interactor activity, membrane" "278", "YKR021W", "16", "-27.7", "strong similarity to hypothetical protein YJL084c, biological_process unknown, molecular_function unknown, cytoplasm" "279", "YNL333W", "47", "-27.6", "putative pyridoxine (vitamin B6) biosynthetic enzyme, SNZ2, thiamin biosynthesis, protein binding, cellular_component unknown" "280", "YGR009C", "17", "-27.6", "protein transport protein, SEC9, vesicle fusion, v-SNARE activity, membrane" "281", "YFL059W", "46", "-27.6", "strong similarity to Para rubber tree ethylene-responsive protein1, SNZ3, thiamin biosynthesis, protein binding, cellular_component unknown" "282", "YJL179W", "22", "-27.6", "Prefoldin subunit 1, PFD1, protein folding, unfolded protein binding, prefoldin complex" "283", "YLR045C", "37", "-27.4", "suppressor of a cs tubulin mutation, STU2, mitotic spindle assembly (sensu Fungi), structural constituent of cytoskeleton, spindle pole body" "284", "YHR181W", "22", "-26.8", "Sed5-Vesicle Protein of 26 kDa, SVP26, biological_process unknown, molecular_function unknown, endoplasmic reticulum" "285", "YJL084C", "71", "-26.4", "similarity to hypothetical protein YKR021w, biological_process unknown, cyclin binding, cytoplasm" "286", "YHR133C", "34", "-26.2", "similarity to hypothetical protein YNL156c, NSG1, biological_process unknown, molecular_function unknown, cellular_component unknown" "287", "YPR055W", "45", "-26.1", "protein transport protein, SEC8, cytokinesis, protein binding, bud tip" "288", "YDR166C", "25", "-26", "required for exocytosis, SEC5, cytokinesis, protein binding, exocyst" "289", "YJR140C", "37", "-25.9", "involved in cell cycle regulation of histone transcription, HIR3, G1/S-specific transcription in mitotic cell cycle, transcription corepressor activity, nucleus" "290", "YPL254W", "17", "-25.6", "transcriptional coactivator, HFI1, transcription from Pol II promoter, transcription cofactor activity, SAGA complex" "291", "YER149C", "27", "-25.6", "involved in oriented growth toward mating partner, PEA2, establishment of cell polarity (sensu Saccharomyces), cytoskeletal regulatory protein binding, actin cap (sensu Fungi)" "292", "YLR078C", "37", "-25.4", "secretory pathway protein, BOS1, ER to Golgi transport, v-SNARE activity, endoplasmic reticulum membrane" "293", "YDR231C", "30", "-25.4", "in the maturation and assembly of cytochrome oxidase involved protein, COX20, aerobic respiration, unfolded protein binding, mitochondrial inner membrane" "294", "YML088W", "10", "-25.3", "involved in degradation of Ho protein, UFO1, ubiquitin-dependent protein catabolism, protein binding, cytoplasm" "295", "YKR029C", "28", "-25.2", "similarity to YJL105w and Lentinula MFBA protein, SET3, histone deacetylation, NAD-dependent histone deacetylase activity, histone deacetylase complex" "296", "YNL257C", "20", "-25.1", "Snf1p protein kinase interacting protein, SIP3, transcription initiation from Pol II promoter, transcription cofactor activity, nucleus" "297", "YHR077C", "44", "-25", "nonsense-mediated mRNA decay protein 2, NMD2, mRNA catabolism, protein binding, cytoplasm" "298", "YGL233W", "40", "-24.9", "vesicular traffic control protein, SEC15, cytokinesis, protein binding, bud tip" "299", "YLL022C", "15", "-24.8", "Hat1 Interacting Factor 1, HIF1, chromatin silencing at telomere, molecular_function unknown, nucleus" "300", "YER087C-B", "22", "-24.5", "involved in translocation into the ER, SBH1, cotranslational membrane targeting, protein transporter activity, translocon" "301", "YNL329C", "33", "-24.3", "peroxisomal assembly protein, PEX6, peroxisome organization and biogenesis, ATPase activity, peroxisome" "302", "YNL156C", "19", "-23.7", "similarity to YHR133c, NSG2, biological_process unknown, molecular_function unknown, endoplasmic reticulum" "303", "YJR032W", "27", "-23.7", "member of the cyclophilin family, CPR7, response to stress, unfolded protein binding, cytosol" "304", "YER143W", "45", "-23.3", "induced in response to DNA alkylation damage, DDI1, ubiquitin-dependent protein catabolism, SNARE binding, plasma membrane" "305", "YKL005C", "17", "-22.8", "Suppressor of ESS1 Prolyl Isomerase interact With RNA Pol II to inhibit Transcription Elongation, BYE1, negative regulation of transcription from Pol II promoter, transcriptional elongation regulator activity, nucleus" "306", "YPL137C", "74", "-22.7", "similarity to microtubule-interacting protein Mhp1p and to hypothetical protein YOR227w, biological_process unknown, molecular_function unknown, cytoplasm" "307", "YDR159W", "38", "-22.6", "leucine permease transcriptional regulator, SAC3, mRNA-nucleus export, protein binding, nuclear pore" "308", "YAL030W", "23", "-22.2", "synaptic vesicle-associated membrane protein, SNC1, endocytosis, v-SNARE activity, transport vesicle" "309", "YOR138C", "31", "-21.9", "weak similarity to TRCDSEMBL:AF175293_2 gene: vanSD sensor protein kinase Enterococcus faecium strain vanD glycopeptide resistance gene cluster, RUP1, biological_process unknown, molecular_function unknown, cytoplasm" "310", "YOR281C", "79", "-21.7", "phosducin homologue, likely to be involved in regulation of pheromone response, PLP2, positive regulation of transcription from Pol II promoter by pheromones, GTPase inhibitor activity, cytoplasm" "311", "YML111W", "22", "-21.6", "strong similarity to ubiquitination protein Bul1p, BUL2, protein monoubiquitination, molecular_function unknown, cytoplasm" "312", "YDR217C", "36", "-21.5", "DNA repair checkpoint protein, RAD9, DNA repair, protein binding, nucleus" "313", "YOR329C", "11", "-21.5", "suppressor of clathrin deficiency, SCD5, actin filament organization, protein binding, actin cortical patch (sensu Fungi)" "314", "YDR219C", "27", "-21.5", "hypothetical protein, ubiquitin-dependent protein catabolism, protein binding, ubiquitin ligase complex" "315", "YDR228C", "27", "-21.4", "component of pre-mRNA 3^-end processing factor CF I, PCF11, mRNA polyadenylylation, protein binding, mRNA cleavage factor complex" "316", "YOL148C", "22", "-21.3", "member of the TBP class of SPT proteins that alter transcription site selection, SPT20, histone acetylation, transcription cofactor activity, SAGA complex" "317", "YMR032W", "13", "-21.3", "involved in cytokinesis, HOF1, cytokinesis, cytoskeletal protein binding, contractile ring (sensu Saccharomyces)" "318", "YDR329C", "22", "-21.1", "peroxisomal assembly protein - peroxin, PEX3, peroxisome organization and biogenesis, molecular_function unknown, peroxisomal membrane" "319", "YCL008C", "2", "-21.1", "required for vacuolar targeting of temperature-sensitive plasma membrane proteins, Ste2p and Can1p, STP22, protein-vacuolar targeting, protein binding, endosome" "320", "YOR181W", "15", "-20.9", "component of actin cortical patches, LAS17, actin filament organization, cytoskeletal protein binding, cytoplasm" "321", "YER148W", "38", "-20.9", "the TATA-binding protein TBP, SPT15, transcription initiation from Pol II promoter, DNA binding, nucleus" "322", "YHL020C", "14", "-20.4", "negative regulator of phospholipid biosynthesis pathway, OPI1, positive regulation of transcription from Pol II promoter, transcription corepressor activity, nucleus" "323", "YDR130C", "19", "-20.3", "weak similarity to sea urchin myosin heavy chain, FIN1, biological_process unknown, protein binding, nucleus" "324", "YOR191W", "30", "-20.2", "similarity to RAD5 protein, RIS1, chromatin assembly or disassembly, DNA-dependent ATPase activity, nucleus" "325", "YGR241C", "13", "-20.2", "Yeast Adaptor Protein, member of AP180 protein family, YAP1802, endocytosis, clathrin binding, actin cortical patch (sensu Fungi)" "326", "YMR200W", "11", "-19.8", "mutant suppresses tor2 mutation, ROT1, cell wall organization and biogenesis, molecular_function unknown, endoplasmic reticulum" "327", "YGR252W", "11", "-19.7", "histone acetyltransferase, GCN5, histone acetylation, histone acetyltransferase activity, SAGA complex" "328", "YBR070C", "7", "-19.5", "osmotolerance protein, biological_process unknown, molecular_function unknown, cellular_component unknown" "329", "YGR120C", "21", "-19.5", "conserved oligomeric golgi complex, COG2, ER to Golgi transport, protein binding, soluble fraction" "330", "YLR008C", "98", "-19.5", "similarity to hypothetical protein YNL328c, PAM18, mitochondrial matrix protein import, unfolded protein binding, presequence translocase-associated import motor" "331", "YLR095C", "27", "-18.9", "weak similarity to hypothetical protein C. elegans, IOC2, chromatin remodeling, protein binding, nucleus" "332", "YGL044C", "22", "-18.9", "component of pre-mRNA 3^-end processing factor CF I, RNA15, mRNA polyadenylylation, cleavage and polyadenylylation specificity factor activity, mRNA cleavage factor complex" "333", "YJL073W", "22", "-18.8", "similarity to heat shock proteins, JEM1, protein folding, unfolded protein binding, endoplasmic reticulum" "334", "YDR054C", "47", "-18.7", "E2 ubiquitin-conjugating enzyme, CDC34, ubiquitin-dependent protein catabolism, ubiquitin-protein ligase activity, cytoplasm" "335", "YIL004C", "23", "-18.6", "protein transport protein, BET1, ER to Golgi transport, v-SNARE activity, endoplasmic reticulum membrane" "336", "YHL002W", "38", "-18.5", "part of Vps27p Hse1p complex, binds ubiquitin and mediates endosomal protein sorting, HSE1, protein-vacuolar targeting, protein binding, endosome" "337", "YDL010W", "26", "-18.4", "similarity to hypothetical protein YBR014c and glutaredoxins, biological_process unknown, molecular_function unknown, vacuole (sensu Fungi)" "338", "YOR076C", "38", "-18.4", "GTPase with function in 3^-to-5^ degradation of mRNA, SKI7, mRNA catabolism, 3'-5' exonuclease activity, cytoplasm" "339", "YDR484W", "25", "-18.2", "ubunit of VP51-54 complex, required for protein sorting at the yeast late Golg, VPS52, Golgi to vacuole transport, protein binding, Golgi apparatus" "340", "YGL098W", "15", "-18.1", "hypothetical protein, USE1, retrograde transport, Golgi to ER, SNAP receptor activity, endoplasmic reticulum" "341", "YGR003W", "16", "-18", "similarity to D.melanogaster lin19 protein, CUL3, ubiquitin-dependent protein catabolism, protein binding, cytoplasm" "342", "YLR090W", "35", "-18", "similarity to E.coli dnaJ, XDJ1, biological_process unknown, chaperone regulator activity, nucleus" "343", "YKL038W", "16", "-18", "regulator of glucose-induced genes, RGT1, glucose metabolism, DNA binding, nucleus" "344", "YDR485C", "11", "-18", "similarity to trichohyalin, VPS72, protein-vacuolar targeting, molecular_function unknown, cytoplasm" "345", "YHL019C", "8", "-17.7", "involved in clathrin-independent transport processes, APM2, vesicle-mediated transport, clathrin binding, AP-1 adaptor complex" "346", "YDR397C", "37", "-17.6", "functional homolog of human NC2beta/Dr1, NCB2, negative regulation of transcription from Pol II promoter, transcription corepressor activity, nucleus" "347", "YNL315C", "61", "-17.6", "F1F0-ATPase complex assembly protein, ATP11, protein complex assembly, unfolded protein binding, mitochondrial matrix" "348", "YKL186C", "28", "-17.6", "MTR2, poly(A)+ mRNA-nucleus export, protein binding, nuclear pore" "349", "YML099C", "15", "-17.3", "transcription factor involved in arginine metabolism, ARG81, arginine metabolism, transcription cofactor activity, nucleus" "350", "YOR367W", "64", "-17.3", "similarity to mammalian smooth muscle protein SM22 and chicken calponin alpha, SCP1, actin filament organization, protein binding, bridging, actin cortical patch (sensu Fungi)" "351", "YPL259C", "12", "-17.2", "AP-1 complex subunit, mu1 subunit, 54 KD, APM1, vesicle-mediated transport, clathrin binding, AP-1 adaptor complex" "352", "YDR265W", "9", "-17.2", "peroxisomal assembly protein - peroxin, PEX10, peroxisome organization and biogenesis, protein binding, peroxisomal membrane" "353", "YLR362W", "27", "-16.9", "ser/thr protein kinase of the MEKK family, STE11, protein amino acid phosphorylation, MAP kinase kinase kinase activity, cytoplasm" "354", "YGL164C", "19", "-16.9", "similarity to S.pombe hypothetical protein SPAC31A2.10, YRB30, biological_process unknown, protein binding, cytoplasm" "355", "YKR090W", "33", "-16.8", "similarity to chicken Lim protein kinase and Islet proteins, PXL1, maintenance of cell polarity (sensu Fungi), protein binding, cytoplasm" "356", "YHR079C", "30", "-16.7", "protein kinase, IRE1, protein amino acid phosphorylation, protein serine/threonine kinase activity, endoplasmic reticulum membrane" "357", "YPR188C", "25", "-16.6", "regulatory light chain (RLC) for Myo1p, is involved in Myo1p ringdisassembly, MLC2, cytokinesis, contractile ring contraction, myosin II binding, contractile ring (sensu Saccharomyces)" "358", "YBR275C", "35", "-16.1", "RAP1-interacting factor 1, RIF1, chromatin silencing at telomere, molecular_function unknown, nuclear telomere cap complex" "359", "YJL115W", "42", "-16", "anti-silencing protein, ASF1, DNA damage response, signal transduction resulting in induction of apoptosis, histone binding, chromatin assembly complex" "360", "YOR357C", "33", "-15.5", "involved in retrieval of late Golgi membrane proteins from the prevacuolar compartment, GRD19, protein localization, protein binding, cytosol" "361", "YKL041W", "15", "-15.5", "endosomal Vps protein complex subunit, VPS24, late endosome to vacuole transport, molecular_function unknown, cytoplasm" "362", "YMR017W", "8", "-15.4", "Dbf2p interacting protein, SPO20, spore wall assembly (sensu Fungi), t-SNARE activity, prospore membrane" "363", "YGL198W", "23", "-15.1", "weak similarity to Yip1p, YIP4, vesicle-mediated transport, Rab interactor activity, membrane" "364", "YDR176W", "30", "-14.3", "general transcriptional adaptor or co-activator, NGG1, histone acetylation, transcription cofactor activity, SAGA complex" "365", "YMR044W", "6", "-13.4", "weak similarity to S. pombe SPBC29A3.13 and crn1 Coronin-like protein, IOC4, chromatin remodeling, protein binding, nucleus" "366", "YMR240C", "18", "-13.1", "U2 snRNP protein, CUS1, spliceosome assembly, protein binding, snRNP U2" "367", "YGL018C", "16", "-12.9", "molecular chaperone, JAC1, aerobic respiration, chaperone binding, mitochondrion" "368", "YBR200W", "31", "-12.8", "bud emergence mediator, BEM1, establishment of cell polarity (sensu Saccharomyces), protein binding, bud neck" "369", "YMR026C", "15", "-12.6", "required for biogenesis of peroxisomes - peroxin, PEX12, peroxisome organization and biogenesis, protein binding, peroxisomal membrane" "370", "YGL051W", "5", "-12.2", "Multicopy suppressor of Sec Twenty-one, MST27, vesicle organization and biogenesis, protein binding, endoplasmic reticulum" "371", "YNL233W", "21", "-12.2", "bud neck involved, BNI4, cytokinesis, protein binding, contractile ring (sensu Saccharomyces)" "372", "YAR033W", "4", "-12.2", "Multicopy suppressor of Sec Twenty one, MST28, vesicle organization and biogenesis, protein binding, endoplasmic reticulum" "373", "YGR068C", "44", "-12.2", "weak similarity to Rod1p, biological_process unknown, molecular_function unknown, cellular_component unknown" "374", "YPL089C", "14", "-12.1", "transcription factor of the MADS box family, RLM1, cell wall organization and biogenesis, DNA binding, nucleus" "375", "YOL067C", "28", "-12.1", "basic helix-loop-helix transcription factor that regulates CIT2 gene expression, RTG1, transcription initiation from Pol II promoter, transcription coactivator activity, cytoplasm" "376", "YHR195W", "14", "-12", "part of nucleus-vacuole junctions, NVJ1, microautophagy, protein binding, nuclear membrane" "377", "YAL055W", "13", "-11.7", "peroxisomal matrix protein import, PEX22, protein-peroxisome targeting, molecular_function unknown, peroxisome" "378", "YPR171W", "43", "-11.7", "hypothetical protein, BSP1, actin cytoskeleton organization and biogenesis, molecular_function unknown, bud neck" "379", "YDR392W", "24", "-11.6", "general transcriptional adaptor or co-activator, SPT3, sporulation (sensu Fungi), transcription cofactor activity, SAGA complex" "380", "YCL029C", "16", "-11.6", "nuclear fusion protein, BIK1, mitotic spindle assembly (sensu Fungi), microtubule binding, spindle pole body" "381", "YHR161C", "25", "-11.4", "Yeast Adaptor Protein, member of AP180 protein family, YAP1801, endocytosis, clathrin binding, actin cortical patch (sensu Fungi)" "382", "YFR013W", "25", "-11.3", "similarity to YOL017w, IOC3, chromatin remodeling, protein binding, nucleus" "383", "YOR371C", "26", "-11.2", "G protein subunit mimic and signaling effector, GPB1, signal transduction, signal transducer activity, cytoplasm" "384", "YMR224C", "15", "-11.2", "DNA repair and meiotic recombination protein, MRE11, DNA repair, protein binding, nucleus" "385", "YJL090C", "16", "-11.1", "involved in DNA replication and S-phase checkpoint, DPB11, DNA replication initiation, epsilon DNA polymerase activity, replication fork" "386", "YER159C", "40", "-11.1", "functional homolog of human NC2alpha, BUR6, negative regulation of transcription from Pol II promoter, transcription corepressor activity, nucleus" "387", "YLR170C", "4", "-10.8", "AP-1 complex subunit, sigma1 subunit, 18 KD, APS1, vesicle-mediated transport, clathrin binding, AP-1 adaptor complex" "388", "YBR152W", "11", "-10.8", "Suppressor of Pre-mRNA Processing mutant, SPP381, nuclear mRNA splicing, via spliceosome, molecular_function unknown, spliceosome complex" "389", "YOR058C", "24", "-10.7", "microtubule-associated protein (nonmotor), ASE1, mitotic spindle assembly (sensu Fungi), microtubule binding, spindle microtubule" "390", "YOR322C", "19", "-10.5", "similarity to hypothetical S.pombe protein SPAC1F12.05, biological_process unknown, molecular_function unknown, cytoplasm" "391", "YJL194W", "20", "-10.5", "cell division control protein, CDC6, pre-replicative complex formation and maintenance, protein binding, pre-replicative complex" "392", "YPL065W", "15", "-10.2", "involved in vacuolar traffic, VPS28, protein-vacuolar targeting, molecular_function unknown, endosome" "393", "YBL008W", "41", "-10.1", "histone transcription regulator, HIR1, regulation of transcription from Pol II promoter, transcription corepressor activity, nucleus" "394", "YDL212W", "28", "-10.1", "endoplasmatic reticulum membrane protein, SHR3, ER to Golgi transport, unfolded protein binding, integral to endoplasmic reticulum membrane" "395", "YNL218W", "16", "-10", "similarity to E.coli hypothetical protein in serS 5^region, MGS1, DNA replication, ATPase activity, nucleus" "396", "YBR098W", "15", "-9.9", "putative transcriptional (co)activator for DNA damage, MMS4, DNA repair, transcription coactivator activity, nucleus" "397", "YDR440W", "15", "-9.7", "putative ATPase, DOT1, chromatin silencing at telomere, protein-lysine N-methyltransferase activity, nucleus" "398", "YDR173C", "17", "-9.6", "arginine metabolism transcription factor, ARG82, arginine metabolism, inositol or phosphatidylinositol kinase activity, nucleus" "399", "YFR022W", "11", "-9.6", "similarity to Rod1p, biological_process unknown, molecular_function unknown, cellular_component unknown" "400", "YNL077W", "6", "-9.6", "similarity to dnaJ protein homolog YDJ1, APJ1, biological_process unknown, unfolded protein binding, cytoplasm" "401", "YDR318W", "6", "-9.3", "outer kinetochore protein, MCM21, chromosome segregation, protein binding, condensed nuclear chromosome kinetochore" "402", "YLL038C", "18", "-9.3", "weak similarity to YJR125c and YDL161w, ENT4, actin filament organization, clathrin binding, actin cortical patch (sensu Fungi)" "403", "YLR417W", "13", "-9.3", "defective in vacuolar protein sorting, VPS36, protein-vacuolar targeting, regulator of G-protein signaling activity, ESCRT II complex" "404", "YDL008W", "3", "-9.1", "subunit of the anaphase promoting complex, APC11, ubiquitin-dependent protein catabolism, protein binding, anaphase-promoting complex" "405", "YMR273C", "25", "-9", "involved in negative regulation of cell polarity, ZDS1, establishment of cell polarity (sensu Saccharomyces), protein binding, cytoplasm" "406", "YBR045C", "7", "-9", "Glc7-interacting protein, GIP1, spore wall assembly (sensu Fungi), protein phosphatase 1 binding, prospore membrane" "407", "YPL138C", "22", "-8.9", "weak similarity to fruit fly polycomblike nuclear protein, SPP1, chromatin silencing at telomere, transcriptional activator activity, nuclear chromatin" "408", "YDR468C", "2", "-8.8", "member of the syntaxin family of t-SNAREs, TLG1, vesicle fusion, v-SNARE activity, Golgi trans face" "409", "YKL197C", "20", "-8.8", "peroxisomal assembly protein - peroxin, PEX1, peroxisome organization and biogenesis, ATPase activity, peroxisome" "410", "YOL044W", "7", "-8.5", "required for peroxisome assembly - peroxin, PEX15, peroxisome organization and biogenesis, molecular_function unknown, peroxisomal membrane" "411", "YOR038C", "44", "-8.5", "histone transcription regulator, HIR2, regulation of transcription from Pol II promoter, transcription corepressor activity, nucleus" "412", "YGR179C", "4", "-8.4", "outer kinetochore protein, OKP1, chromosome segregation, protein binding, condensed nuclear chromosome kinetochore" "413", "YGR112W", "9", "-8.2", "SURF homologue protein, SHY1, aerobic respiration, unfolded protein binding, mitochondrial inner membrane" "414", "YDR103W", "42", "-8.2", "pheromone signal transduction pathway protein, STE5, signal transduction during conjugation with cellular fusion, MAP-kinase scaffold activity, cytoplasm" "415", "YJR156C", "81", "-8.2", "thiamine regulated gene, homologous to nmt1a in S. pombe, THI11, thiamin biosynthesis, protein binding, cellular_component unknown" "416", "YIL154C", "10", "-8", "sugar utilization regulatory protein, IMP2', DNA repair, transcription coactivator activity, cytoplasm" "417", "YHR156C", "9", "-7.9", "weak similarity to mouse kinesin KIF3B, LIN1, biological_process unknown, protein binding, nucleus" "418", "YAL056W", "20", "-7.7", "G protein subunit mimic and signaling effector, GPB2, signal transduction, signal transducer activity, cytoplasm" "419", "YPL187W", "3", "-7.7", "mating pheromone alpha-1 precursor, MF(ALPHA)1, response to pheromone during conjugation with cellular fusion, pheromone activity, extracellular" "420", "YPR030W", "30", "-7.7", "similarity to YBL101c, CSR2, cell wall organization and biogenesis, molecular_function unknown, nucleus" "421", "YML132W", "12", "-7.6", "strong similarity to subtelomeric encoded proteins, COS3, biological_process unknown, molecular_function unknown, vacuole (sensu Fungi)" "422", "YCL067C", "13", "-7.6", "mating type regulatory protein, silenced copy at HML, HMLALPHA2, regulation of transcription from Pol II promoter, transcription corepressor activity, nucleus" "423", "YMR077C", "9", "-7.6", "similarity to SNF7 protein, VPS20, late endosome to vacuole transport, molecular_function unknown, cytoplasm" "424", "YCR039C", "13", "-7.6", "mating type regulatory protein, expressed copy at MAT locus, MATALPHA2, regulation of transcription from Pol II promoter, transcription corepressor activity, nucleus" "425", "YLR128W", "4", "-7.6", "similarity to S.pombe hypothetical protein SPBC24E9, DCN1, biological_process unknown, molecular_function unknown, cellular_component unknown" "426", "YOL072W", "16", "-7.5", "weak similarity to hypothetical protein C. elegans, THP1, bud site selection, protein binding, nuclear pore" "427", "YNL214W", "5", "-7.4", "component of the peroxisomal protein translocation - peroxin, PEX17, peroxisome organization and biogenesis, protein binding, peroxisomal membrane" "428", "YKL002W", "12", "-7.4", "class E vacuolar-protein sorting and endocytosis factor, DID4, late endosome to vacuole transport, protein binding, cytoplasm" "429", "YLR191W", "11", "-7.3", "peroxisomal protein involved in protein import - peroxin, PEX13, peroxisome organization and biogenesis, protein binding, peroxisomal membrane" "430", "YAL014C", "10", "-7.3", "hypothetical protein, SYN8, transport, SNAP receptor activity, endosome" "431", "YPL242C", "29", "-7.3", "involved in cytokinesis, has similarity to mammalian IQGAP proteins, IQG1, actin filament organization, cytoskeletal protein binding, contractile ring (sensu Saccharomyces)" "432", "YDR448W", "7", "-7.1", "general transcriptional adaptor or co-activator, ADA2, histone acetylation, transcription coactivator activity, SAGA complex" "433", "YKR020W", "16", "-7", "subunit of VP51-54 complex, required for protein sorting at the yeast late Golgi, VPS51, protein-vacuolar targeting, protein binding, Golgi apparatus" "434", "YDR113C", "10", "-6.9", "cell cycle regulator, PDS1, mitotic sister chromatid segregation, protein binding, nucleus" "435", "YDR306C", "6", "-6.9", "weak similarity to S.pombe hypothetical protein SPAC6F6, ubiquitin-dependent protein catabolism, protein binding, ubiquitin ligase complex" "436", "YJR102C", "3", "-6.9", "weak similarity to hypothetical protein D. melanogaster, VPS25, protein-vacuolar targeting, molecular_function unknown, ESCRT II complex" "437", "YGL212W", "14", "-6.8", "vacuolar morphogenesis protein, VAM7, vesicle fusion, v-SNARE activity, vacuolar membrane (sensu Fungi)" "438", "YGL116W", "15", "-6.8", "cell division control protein, CDC20, ubiquitin-dependent protein catabolism, enzyme activator activity, anaphase-promoting complex" "439", "YOR372C", "6", "-6.5", "protein required for nuclear division, NDD1, G2/M-specific transcription in mitotic cell cycle, transcriptional activator activity, nucleus" "440", "YMR159C", "3", "-6.3", "coiled-coil protein required for autophagy, ATG16, autophagy, molecular_function unknown, membrane fraction" "441", "YPR031W", "14", "-6.2", "similarity to human zinc-finger protein BR140, NTO1, biological_process unknown, molecular_function unknown, cytoplasm" "442", "YJL204C", "13", "-6.1", "involved in recycling of the SNARE Snc1p , RCY1, endocytosis, protein binding, site of polarized growth (sensu Saccharomyces)" "443", "YLR119W", "11", "-6.1", "suppressor of rna1-1 mutation, SRN2, protein-vacuolar targeting, molecular_function unknown, endosome" "444", "YJR004C", "13", "-6", "alpha-agglutinin, SAG1, agglutination during conjugation with cellular fusion, cell adhesion molecule binding, cell wall (sensu Fungi)" "445", "YLR011W", "4", "-6", "weak similarity to E.coli hypothetical 20.4 kDa protein, LOT6, biological_process unknown, molecular_function unknown, cytoplasm" "446", "YBR158W", "33", "-5.9", "weak similarity to TRCDSEMBL:AF176518_1 F-box protein FBL2; human, AMN1, negative regulation of exit from mitosis, protein binding, cytoplasm" "447", "YLR393W", "5", "-5.7", "F1F0 ATPase complex assembly protein, ATP10, protein complex assembly, molecular_function unknown, mitochondrial membrane" "448", "YDR252W", "5", "-5.4", "alternate beta subunit of the nascent polypeptide-associated complex, BTT1, nascent polypeptide association, unfolded protein binding, cytosolic ribosome (sensu Eukarya)" "449", "YPL018W", "10", "-5.3", "outer kinetochore protein, CTF19, chromosome segregation, protein binding, nucleus" "450", "YBR233W-A", "7", "-5.3", "outer kinetochore protein - part of Dam1 complex, DAD3, mitosis, protein binding, spindle" "451", "YLR381W", "24", "-5.3", "outer kinetochore protein, CTF3, chromosome segregation, protein binding, condensed nuclear chromosome kinetochore" "452", "YOR106W", "11", "-5", "syntaxin (t-SNARE), VAM3, vesicle fusion, t-SNARE activity, vacuolar membrane" "453", "YHR142W", "3", "-4.9", "control of protein export from the ER (like chitin synthase III), CHS7, ER to Golgi transport, molecular_function unknown, endoplasmic reticulum membrane" "454", "YGL032C", "5", "-4.8", "a-agglutinin binding subunit, AGA2, agglutination during conjugation with cellular fusion, cell adhesion molecule binding, cell wall (sensu Fungi)" "455", "YOR349W", "17", "-4.8", "chromosome segregation protein, CIN1, post-chaperonin tubulin folding pathway, beta-tubulin binding, cellular_component unknown" "456", "YNL148C", "7", "-4.8", "similarity to human tubulin folding cofactor B, ALF1, post-chaperonin tubulin folding pathway, microtubule binding, cytoplasm" "457", "YCL032W", "10", "-4.8", "pheromone response pathway protein, STE50, signal transduction during conjugation with cellular fusion, protein kinase regulator activity, cytoplasm" "458", "YCR060W", "12", "-4.1", "similarity to stress inducible protein Sti1p, TAH1, biological_process unknown, molecular_function unknown, cytoplasm" "459", "YKL090W", "4", "-4.1", "hypothetical protein, CUE2, biological_process unknown, protein binding, cellular_component unknown" "460", "YOR036W", "11", "-4", "syntaxin (T-SNARE), vacuolar, PEP12, Golgi to vacuole transport, t-SNARE activity, Golgi apparatus" "461", "YPL174C", "10", "-3.9", "component of the dynactin complex, NIP100, mitotic anaphase B, protein binding, dynactin complex" "462", "YBR290W", "6", "-3.5", "metal homeostasis protein, BSD2, protein-vacuolar targeting, molecular_function unknown, endoplasmic reticulum" "463", "YAL031C", "15", "-3.3", "hypothetical protein, FUN21, biological_process unknown, molecular_function unknown, cytoplasm" "464", "YDR309C", "8", "-3.2", "Cdc42 GTPase-binding protein, GIC2, establishment of cell polarity (sensu Saccharomyces), small GTPase regulatory/interacting protein activity, bud tip" "465", "YGR188C", "28", "-3.1", "ser/thr protein kinase, BUB1, protein amino acid phosphorylation, protein binding, nucleus" "466", "YDR285W", "25", "-3.1", "synaptonemal complex protein, ZIP1, meiosis, chromatin binding, synaptonemal complex" "467", "YOR064C", "3", "-3.1", "component of histone acetyltransferase complex, has similarity to human retinoblastoma binding protein 2, YNG1, histone acetylation, molecular_function unknown, histone acetyltransferase complex" "468", "YLR313C", "8", "-2.7", "required for bipolar bud site selection, SPH1, establishment of cell polarity (sensu Saccharomyces), cytoskeletal regulatory protein binding, bud neck" "469", "YGL003C", "4", "-2.6", "substrate-specific activator of APC-dependent proteolysis, CDH1, ubiquitin-dependent protein catabolism, enzyme activator activity, cytoplasm" "470", "YGL183C", "2", "-2.6", "Mnd1/Hop2 complex promote meiotic chromosome pairing and DSB repair, MND1, meiotic recombination, molecular_function unknown, condensed nuclear chromosome" "471", "YPL002C", "18", "-2.5", "involved in glucose derepression, SNF8, protein-vacuolar targeting, molecular_function unknown, ESCRT II complex" "472", "YIL150C", "23", "-2.5", "required for S-phase initiation or completion, MCM10, DNA replication initiation, chromatin binding, nucleus" "473", "YER051W", "13", "-2.4", "similarity to C.elegans hypothetical protein, biological_process unknown, molecular_function unknown, cellular_component unknown" "474", "YOR178C", "9", "-2.4", "ser/thr phosphoprotein phosphatase 1, regulatory chain, GAC1, meiosis, protein phosphatase type 1 activity, protein phosphatase type 1 complex" "475", "YBR044C", "26", "-2.4", "chaperone required for assembly of mitochondrial succinate dehydrogenase, TCM62, protein complex assembly, unfolded protein binding, mitochondrial inner membrane" "476", "YOL082W", "12", "-2.4", "Protein involved in autophagocytosis during starvation, ATG19, protein-vacuolar targeting, protein binding, cytoplasm" "477", "YDR223W", "1", "-2.2", "similarity to Ifh1p, CRF1, biological_process unknown, molecular_function unknown, cellular_component unknown" "478", "YDL239C", "11", "-2.1", "hypothetical protein, ADY3, protein complex assembly, protein binding, spindle" "479", "YNL145W", "1", "-2", "mating pheromone a-factor 2, MFA2, signal transduction during conjugation with cellular fusion, pheromone activity, extracellular" "480", "YBR201W", "3", "-2", "involved in degradation proteins in the ER, DER1, ER-associated protein catabolism, molecular_function unknown, endoplasmic reticulum membrane" "481", "YMR163C", "12", "-2", "hypothetical protein, biological_process unknown, molecular_function unknown, cytoplasm" "482", "YLR423C", "5", "-1.9", "protein involved in authophagy, ATG17, autophagy, kinase activator activity, cytoplasm" "483", "YOR391C", "3", "-1.7", "strong similarity to YMR322c and YDR533c, identical to YPL280w, HSP33, biological_process unknown, unfolded protein binding, cellular_component unknown" "484", "YMR322C", "3", "-1.7", "strong similarity to YPL280w, YOR391c and YDR533c, SNO4, pyridoxine metabolism, unfolded protein binding, cellular_component unknown" "485", "YPL280W", "3", "-1.7", "strong similarity to YMR322c and YDR533c, HSP32, biological_process unknown, unfolded protein binding, cellular_component unknown" "486", "YJR135C", "9", "-1.7", "outer kinetochore protein, MCM22, chromosome segregation, protein binding, condensed nuclear chromosome kinetochore" "487", "YOR279C", "3", "-1.6", "hypothetical protein, RFM1, chromatin silencing, unfolded protein binding, nucleus" "488", "YGR239C", "1", "-1.6", "peroxin, essential for peroxisomal targeting by the PTS2 pathway, PEX21, protein-peroxisome targeting, protein binding, cytosol" "489", "YGR142W", "4", "-1.6", "Gene/protein whose expression is elevated in a btn1 minus/Btn1p lacking yeast strain, BTN2, intracellular protein transport, molecular_function unknown, cytosol" "490", "YDR076W", "2", "-1.5", "DNA repair protein, RAD55, DNA recombinase assembly, protein binding, nucleus" "491", "YHR090C", "5", "-1.5", "component of NuA4 histone acetyltransferase complex, YNG2, chromatin modification, enzyme activator activity, nucleus" "492", "YLR102C", "4", "-1.5", "subunit of the Anaphase Promoting Complex, APC9, ubiquitin-dependent protein catabolism, protein binding, anaphase-promoting complex" "493", "YER007W", "3", "-1.5", "involved in the stabilization of microtubles, PAC2, post-chaperonin tubulin folding pathway, alpha-tubulin binding, cellular_component unknown" "494", "YLR224W", "5", "-1.4", "hypothetical protein, ubiquitin-dependent protein catabolism, protein binding, ubiquitin ligase complex" "495", "YOL002C", "2", "-1.4", "Implicated in Zinc Homeostasis, membran protein, IZH2, lipid metabolism, metal ion binding, membrane" "496", "YEL005C", "2", "-1.4", "Vac8p binding protein of 31 kDa, VAB2, biological_process unknown, protein binding, cytoplasm" "497", "YNR044W", "1", "-1.4", "a-agglutinin anchor subunit, AGA1, agglutination during conjugation with cellular fusion, cell adhesion molecule binding, cell wall (sensu Fungi)" "498", "YNL188W", "6", "-1.4", "cell division control protein, KAR1, spindle pole body duplication (sensu Saccharomyces), protein binding, half bridge of spindle pole body" "499", "YDR461W", "5", "-1.3", "mating pheromone a-factor 1, MFA1, signal transduction during conjugation with cellular fusion, pheromone activity, soluble fraction" "500", "YOR269W", "3", "-1.3", "similarity to human LIS-1 protein, PAC1, nuclear migration (sensu Saccharomyces), molecular_function unknown, cytoplasm" "501", "YLR254C", "1", "-1.2", "weak similarity to PIR:T10472 G-box binding protein 2A Sinapis alba, biological_process unknown, molecular_function unknown, cytoplasm" "502", "YHR061C", "3", "-1.2", "Cdc42 GTPase-binding protein, GIC1, establishment of cell polarity (sensu Saccharomyces), small GTPase regulatory/interacting protein activity, bud neck" "503", "YDR004W", "1", "-1.1", "DNA repair protein, RAD57, telomerase-independent telomere maintenance, protein binding, nucleus" "504", "YHR199C-A", "2", "-1.1", "biological_process unknown, molecular_function unknown, cellular_component unknown" "505", "YCR097W", "1", "-0.3", "mating type regulatory protein, silenced copy at HMR locus, HMRA1, regulation of transcription, mating-type specific, transcription corepressor activity, nucleus" "506", "YJL210W", "2", "-0.2", "peroxisomal assembly protein - peroxin, PEX2, peroxisome organization and biogenesis, protein binding, peroxisomal membrane" "507", "YCL066W", "2", "0", "mating type regulatory protein, silenced copy at HML, HMLALPHA1, regulation of transcription from Pol II promoter, transcription coactivator activity, nucleus" "508", "YCR040W", "2", "0", "mating type regulatory protein, expressed copy at MAT locus, MATALPHA1, regulation of transcription from Pol II promoter, transcription coactivator activity, nucleus" "509", "YOR075W", "1", "0", "syntaxin (T-SNARE) of the ER, UFE1, vesicle fusion, t-SNARE activity, endoplasmic reticulum membrane" out of 520